YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|39985317, gi\|...
Organism:	Geobacter sulfurreducens PCA
Length:	224 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|39985317, gi|....

Description	E-value	Query Range	Subject Range
CYSG_PSEE4 - Siroheme synthase OS=Pseudomonas entomophila (strain L48) GN=cysG PE=3 SV=1 gi\|95110329 - gi\|95110329\|emb\|CAK15036.1\| Siroheme synthase [Pseudomonas entomophila L48]	224.0	[0..1]	[208..1]
CYSG_PHOLL - Siroheme synthase OS=Photorhabdus luminescens subsp. laumondii GN=cysG PE=3 SV=1 CYSG_PHOLL - Siroheme synthase OS=Photorhabdus luminescens subsp. laumondii (strain DSM 15139 / CIP 105565 / TT01...	224.0	[0..1]	[205..1]
CYSG2_YERPS - Siroheme synthase 2 OS=Yersinia pseudotuberculosis GN=cysG2 PE=3 SV=1 CYSG2_YERPS - Siroheme synthase 2 OS=Yersinia pseudotuberculosis serotype I (strain IP32953) GN=cysG2 PE=3 SV=1 gi\|170022493, gi... - gi\|170022493\|ref\|YP_001718998.1\| siroheme synthase [Yersinia pseudotuberculosis YPIII], gi\|169749027... CYSG2_YERP3 - Siroheme synthase 2 OS=Yersinia pseudotuberculosis serotype O:1b (strain IP 31758) GN=cysG2 PE=3 SV=...	223.0	[0..1]	[212..1]
CYSG_PSEA7 - Siroheme synthase OS=Pseudomonas aeruginosa (strain PA7) GN=cysG PE=3 SV=1	222.0	[0..1]	[205..1]
CYSG_PSEAE - Siroheme synthase OS=Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228) GN... CYSG_PSEAE - Siroheme synthase OS=Pseudomonas aeruginosa GN=cysG PE=3 SV=1 gi\|254235597, gi... - gi\|84320580\|ref\|ZP_00968953.1\| COG0007: Uroporphyrinogen-III methylase [Pseudomonas aeruginosa C3719... gi\|107102133 - gi\|107102133\|ref\|ZP_01366051.1\| hypothetical protein PaerPA_01003182 [Pseudomonas aeruginosa PACS2]	221.0	[0..1]	[207..1]
gi\|126194422, gi... - gi\|84326938\|ref\|ZP_00974962.1\| COG0007: Uroporphyrinogen-III methylase [Pseudomonas aeruginosa 2192]...	221.0	[0..1]	[205..1]
CYSG_PSEAB - Siroheme synthase OS=Pseudomonas aeruginosa (strain UCBPP-PA14) GN=cysG PE=3 SV=1	220.0	[0..1]	[205..1]
gi\|77975034, gi\|... - gi\|77975034\|ref\|ZP_00830571.1\| COG0007: Uroporphyrinogen-III methylase [Yersinia frederiksenii ATCC ...	219.0	[0..1]	[214..1]
CYSG_PSEF5 - Siroheme synthase OS=Pseudomonas fluorescens (strain Pf-5 / ATCC BAA-477) GN=cysG PE=3 SV=1	219.0	[0..1]	[205..1]
CYSG_PSEPF - Siroheme synthase OS=Pseudomonas fluorescens (strain Pf0-1) GN=cysG PE=3 SV=1	217.0	[0..1]	[211..1]

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Predicted Domain #1

Region A:
Residues: [1-224]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTLLPISINV SGRLVTIVGG GGVARRKCLS LLEAGARVTV VAPRLDERLM KLADEGAICL  60
   61 AQRPYADGDL AGSVLAYAAT DDPAVNRAVA EEAHNRGIPV DVTDDPERGS FTSPAVLRRG 120
  121 DLVIAVSTGG GAPGFAARVR DDIAEIIGQE YAETLLILGA IREKLLTASK NAAYNKHILH 180
  181 DLSAAPLPEM VRSRNFEELD RTLARIAGPD FTLENLGFGR KDSP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	53.69897
Match:	1pjqA
Description:	Structure and function of CysG, the multifunctional methyltransferase/dehydrogenase/ferrochelatase for siroheme synthesis
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	2.16785883389468	bayes_pls_golite062009
oxidoreductase activity	1.13814306448308	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: