YRC Public Data Repository - Protein Structure Prediction

Protein:	HIS12_GEOSL
Organism:	Geobacter sulfurreducens PCA
Length:	212 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HIS12_GEOSL.

Description	E-value	Query Range	Subject Range
HIS1_GEOMG - ATP phosphoribosyltransferase OS=Geobacter metallireducens (strain GS-15 / ATCC 53774 / DSM 7210) GN...	290.0	[0..1]	[212..1]
gi\|88916666, gi\|... - gi\|88936608\|ref\|ZP_01142213.1\| ATP phosphoribosyltransferase [Geobacter uraniumreducens Rf4], gi\|889...	289.0	[0..1]	[212..23]
gi\|221563080, gi... - gi\|222053791\|ref\|YP_002536153.1\| ATP phosphoribosyltransferase [Geobacter sp. FRC-32], gi\|221563080\|...	287.0	[0..1]	[212..1]
gi\|71740099, gi\|... - gi\|71839403\|ref\|ZP_00679152.1\| ATP phosphoribosyltransferase [Pelobacter propionicus DSM 2379], gi\|7...	284.0	[0..1]	[212..1]
HIS1_PELCD - ATP phosphoribosyltransferase OS=Pelobacter carbinolicus (strain DSM 2380 / Gra Bd 1) GN=hisG PE=3 S...	284.0	[0..1]	[212..1]
gi\|95929010, gi\|... - gi\|95929010\|ref\|ZP_01311755.1\| ATP phosphoribosyltransferase [Desulfuromonas acetoxidans DSM 684], g...	280.0	[0..1]	[212..1]
HIS1_BURVG - ATP phosphoribosyltransferase OS=Burkholderia vietnamiensis (strain G4 / LMG 22486) GN=hisG PE=3 SV=...	274.0	[0..1]	[211..1]
HIS1_BURA4 - ATP phosphoribosyltransferase OS=Burkholderia ambifaria (strain MC40-6) GN=hisG PE=3 SV=1 HIS1_BURCM - ATP phosphoribosyltransferase OS=Burkholderia ambifaria (strain ATCC BAA-244 / AMMD) GN=hisG PE=3 SV... gi\|170135600, gi... - gi\|170699513\|ref\|ZP_02890555.1\| ATP phosphoribosyltransferase [Burkholderia ambifaria IOP40-10], gi\|... gi\|171316481, gi... - gi\|171316481\|ref\|ZP_02905698.1\| ATP phosphoribosyltransferase [Burkholderia ambifaria MEX-5], gi\|171...	273.0	[0..1]	[211..1]
HIS1_BURCE - ATP phosphoribosyltransferase - Burkholderia cepacia (Pseudomonas cepacia) HIS1_BURM1 - ATP phosphoribosyltransferase OS=Burkholderia multivorans (strain ATCC 17616 / 249) GN=hisG PE=3 SV=... HIS1_BURML - (Q845V4) ATP phosphoribosyltransferase (EC 2.4.2.17) (ATP-PRTase) (ATP-PRT) gi\|221166870, gi... - gi\|221213418\|ref\|ZP_03586393.1\| ATP phosphoribosyltransferase [Burkholderia multivorans CGD1], gi\|22...	273.0	[0..1]	[211..1]
gi\|254246530, gi... - gi\|84356586\|ref\|ZP_00981428.1\| COG0040: ATP phosphoribosyltransferase [Burkholderia cenocepacia PC18... HIS1_BURCH - ATP phosphoribosyltransferase OS=Burkholderia cenocepacia (strain HI2424) GN=hisG PE=3 SV=1 HIS1_BURCA - ATP phosphoribosyltransferase OS=Burkholderia cenocepacia (strain AU 1054) GN=hisG PE=3 SV=1 HIS1_BURCJ - ATP phosphoribosyltransferase OS=Burkholderia cenocepacia (strain ATCC BAA-245 / DSM 16553 / LMG 166...	273.0	[0..1]	[211..1]

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Predicted Domain #1

Region A:
Residues: [1-212]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTDYITIAIP KGRILEESVT LFGKIGINCD ELLSNTRKLI FENHEQRMRY MIVRATDVPT  60
   61 YVEYGCADLG IVGKDTLMEQ EKDLYEPLDL KFGYCRMMVA EPAGLALDDD PSSWTNIRIA 120
  121 TKYPNVTEKY FARKGVQVEI IKLYGSIELA PLVGLSERIV DLVSTGETLR QNGLVEVETI 180
  181 AEITTRLIVN RASLKTKHPR ITEIIEGLEK HV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	66.522879
Match:	1h3dA
Description:	STRUCTURE OF THE E.COLI ATP-PHOSPHORIBOSYLTRANSFERASE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ATP phosphoribosyltransferase activity	2.05227933205562	bayes_pls_golite062009
catalytic activity	1.04475291968158	bayes_pls_golite062009
transferase activity, transferring pentosyl groups	0.62944815546517	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: