YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|39985015, gi\|...
Organism:	Geobacter sulfurreducens PCA
Length:	163 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|39985015, gi|....

Description	E-value	Query Range	Subject Range
gi\|24377344, gi\|... - gi\|24379413\|ref\|NP_721368.1\| putative 2-amino-4-hydroxy-6-hydroxymethylpteridine pyrophosphokinase [... gi\|254997475 - gi\|254997475\|dbj\|BAH88076.1\| putative 2-amino-4-hydroxy-6- hydroxymethylpteridine pyrophosphokinase ...	212.0	[0..3]	[158..2]
gi\|10172707, gi\|... - gi\|15612658\|ref\|NP_240961.1\| 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin e pyrophosphokinase [B... gi\|25288328 - pir\|\|G83661 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin e pyrophosphokinase folK [imported] - B...	206.0	[0..1]	[161..1]
gi\|110549696, gi... - gi\|222054010\|ref\|YP_002536372.1\| 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase...	206.0	[0..3]	[162..15]
gi\|82775534, gi\|... - gi\|82775534\|ref\|YP_401881.1\| 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase [Shi...	205.0	[0..3]	[153..2]
gi\|78221716, gi\|... - gi\|78221716\|ref\|YP_383463.1\| 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase [Geobacter metallir...	204.0	[0..3]	[162..9]
gi\|28807503 - gi\|28807503\|dbj\|BAC60768.1\| 2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase [Vi... gi\|28899279, gi\|... - gi\|28899279\|ref\|NP_798884.1\| 2-amino-4-hydroxy-6-hydroxymethyldihydropteridin e pyrophosphokinase [V... gi\|153840011, gi... - gi\|153840011\|ref\|ZP_01992678.1\| 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase ...	203.0	[0..4]	[158..3]
gi\|56412459, gi\|... - gi\|56412459\|ref\|YP_149534.1\| 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase [Sal... gi\|197361395, gi... - gi\|197361395\|ref\|YP_002141030.1\| 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase ...	202.0	[0..3]	[154..2]
gi\|116183347, gi... - gi\|75853807\|ref\|ZP_00761565.1\| COG0801: 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase [Vibrio ...	202.0	[0..4]	[158..3]
gi\|254791277, gi... - gi\|254791277\|ref\|YP_003076114.1\| 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase ... gi\|208734565, gi... - gi\|208813288\|ref\|ZP_03254617.1\| 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase ... gi\|208807071, gi... - gi\|208807071\|ref\|ZP_03249408.1\| 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase ... gi\|195938176 - gi\|195938176\|ref\|ZP_03083558.1\| 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase [... gi\|168801480, gi... - gi\|189376408\|gb\|EDU94824.1\| 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase [Esc... gi\|217320725, gi... - gi\|217324504\|ref\|ZP_03440588.1\| 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase ... gi\|209746108, gi... - pir\|\|B85498 hypothetical protein folK [imported] - Escherichia coli (strain O157:H7, substrain EDL9... gi\|209398080, gi... - gi\|209398080\|ref\|YP_002268751.1\| 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase... gi\|208741904, gi... - gi\|208821781\|ref\|ZP_03262101.1\| 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase ... gi\|12512860, gi\|... - gi\|15799826\|ref\|NP_285838.1\| 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase [Esc... gi\|13359602, gi\|... - gi\|15829400\|ref\|NP_308173.1\| 2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase [Esc... gi\|168764714, gi... - gi\|189365314\|gb\|EDU83730.1\| 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase [Esc... gi\|13359602, gi\|... - gi\|15829400\|ref\|NP_308173.1\| 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase [Escherichia coli O... gi\|189357085, gi... - gi\|189357085\|gb\|EDU75504.1\| 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase [Esc... gi\|188014557, gi... - gi\|188014557\|gb\|EDU52679.1\| 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase [Esc... gi\|168789250, gi... - gi\|189371091\|gb\|EDU89507.1\| 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase [Esc... gi\|189000384, gi... - gi\|189000384\|gb\|EDU69370.1\| 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase [Esc... gi\|187767838, gi... - gi\|187767838\|gb\|EDU31682.1\| 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase [Esc... gi\|189360702, gi... - gi\|189360702\|gb\|EDU79121.1\| 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase [Esc...	202.0	[0..3]	[154..2]
gi\|37524868, gi\|... - gi\|37524868\|ref\|NP_928212.1\| 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokina se [Photorhabdus lumi...	202.0	[0..3]	[158..2]

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Predicted Domain #1

Region A:
Residues: [1-163]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MESNVFIALG SNMGDRELNL LRAVAEIGKL PETRITALSG FYETEPVGPV PEQPDFLNAV  60
   61 LRIETSLTPH RLLEELQRIE TGLFGRRREM YQGPRSMDLD ILLYGSLTVA VEGLVIPHPR 120
  121 LHQRHFVLVP LAEIAPDMIH PVQEKPVREL LASLPPGERV TKT

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	52.154902
Match:	1dy3A
Description:	6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase, HPPK
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity	5.95418117400583	bayes_pls_golite062009
diphosphotransferase activity	4.79017391246148	bayes_pls_golite062009
catalytic activity	2.44295736158702	bayes_pls_golite062009
transferase activity	1.5312510694044	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	1.34283740138285	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: