YRC Public Data Repository - Protein Structure Prediction

Protein:	RSMA_GEOSL
Organism:	Geobacter sulfurreducens PCA
Length:	276 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RSMA_GEOSL.

Description	E-value	Query Range	Subject Range
RSMA_PHOLL, KSGA... - Ribosomal RNA small subunit methyltransferase A OS=Photorhabdus luminescens subsp. laumondii GN=rsmA... RSMA_PHOLL - Ribosomal RNA small subunit methyltransferase A OS=Photorhabdus luminescens subsp. laumondii (strain...	258.0	[0..3]	[272..6]
gi\|171988601, gi... - gi\|68055892\|ref\|ZP_00540031.1\| RRNA 16S rRNA dimethylase [Exiguobacterium sibiricum 255-15], gi\|6800...	256.0	[0..1]	[269..14]
gi\|242244296, gi... - gi\|242244296\|ref\|ZP_04798733.1\| dimethyladenosine transferase [Streptococcus pneumoniae TCH8431/19A]... RSMA_STRPJ - Ribosomal RNA small subunit methyltransferase A OS=Streptococcus pneumoniae (strain ATCC 700669 / Sp... gi\|183571617, gi... - gi\|183571617\|gb\|EDT92145.1\| dimethyladenosine transferase [Streptococcus pneumoniae SP195], gi\|16848... KSGA_STRPN, RSMA... - Ribosomal RNA small subunit methyltransferase A OS=Streptococcus pneumoniae GN=rsmA PE=3 SV=2, Dimet... gi\|147929973, gi... - gi\|149021935\|ref\|ZP_01835922.1\| dimethyladenosine transferase [Streptococcus pneumoniae SP23-BS72], ... gi\|147928127, gi... - gi\|148993153\|ref\|ZP_01822719.1\| dimethyladenosine transferase [Streptococcus pneumoniae SP9-BS68], g... RSMA_STRPN - Ribosomal RNA small subunit methyltransferase A OS=Streptococcus pneumoniae serotype 4 (strain ATCC ... RSMA_STRZT - Ribosomal RNA small subunit methyltransferase A OS=Streptococcus pneumoniae (strain Taiwan19F-14) GN...	254.0	[0..1]	[273..13]
RSMA_STRP2 - Ribosomal RNA small subunit methyltransferase A OS=Streptococcus pneumoniae serotype 2 (strain D39 /... gi\|168492040, gi... - gi\|183573705\|gb\|EDT94233.1\| dimethyladenosine transferase [Streptococcus pneumoniae CDC0288-04], gi\|... gi\|25286073 - gi\|25286073\|pir\|\|E98096 dimethyladenosine transferase (EC 2.1.1.-) [imported] - Streptococcus pneumo... RSMA_STRR6 - Ribosomal RNA small subunit methyltransferase A OS=Streptococcus pneumoniae (strain ATCC BAA-255 / R...	253.0	[0..1]	[273..13]
gi\|134297956, gi... - gi\|88947021\|ref\|ZP_01150050.1\| RRNA 16S rRNA dimethylase [Desulfotomaculum reducens MI-1], gi\|889235...	253.0	[0..1]	[271..14]
RSMA_GEOMG - Ribosomal RNA small subunit methyltransferase A OS=Geobacter metallireducens (strain GS-15 / ATCC 53...	253.0	[0..1]	[274..1]
gi\|84375694, gi\|... - gi\|84393695\|ref\|ZP_00992445.1\| dimethyladenosine transferase [Vibrio splendidus 12B01], gi\|84375694\|...	252.0	[0..3]	[271..6]
gi\|85834110, gi\|... - gi\|86148123\|ref\|ZP_01066423.1\| dimethyladenosine transferase [Vibrio sp. MED222], gi\|85834110\|gb\|EAQ... RSMA_VIBTL - Ribosomal RNA small subunit methyltransferase A OS=Vibrio tasmaniensis (strain LGP32) GN=rsmA PE=3 S...	251.0	[0..3]	[272..6]
RSMA_BACHD - Ribosomal RNA small subunit methyltransferase A OS=Bacillus halodurans (strain ATCC BAA-125 / DSM 18... RSMA_BACHD, KSGA... - Ribosomal RNA small subunit methyltransferase A OS=Bacillus halodurans GN=rsmA PE=3 SV=1, Dimethylad...	251.0	[0..1]	[272..15]

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Predicted Domain #1

Region A:
Residues: [1-276]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRGDGIRARK ALGQNFLTDR SVLSRIAALV SAGAGERILE IGPGKGALTS YLAEQAGQLV  60
   61 AVELDDRLVP LLRGSFAGNP SVTIIEGDIL DLDLRETLGR YGTPPWKVAA NLPYNISTPV 120
  121 LFRLLDARDL FSRLVLMLQK EVGNRLAAGP GSKEYGVLSV LFQLHFDVTR EILVRPGSFH 180
  181 PVPKVDSVVL LFVPLAQPRV DVGDEDYFRR VVKASFAMRR KTLWNCLKGG ALGVPTDGIR 240
  241 DVLARCGIDE GRRGETLSLQ EFASLTKGLL AAGGSL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	59.0
Match:	1qyrA
Description:	2.1 Angstrom Crystal structure of KsgA: A Universally Conserved Adenosine Dimethyltransferase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
methyltransferase activity	4.15445027778357	bayes_pls_golite062009
rRNA methyltransferase activity	4.09362182773099	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	4.07153733729662	bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity	3.39429041855776	bayes_pls_golite062009
RNA methyltransferase activity	3.07428840534971	bayes_pls_golite062009
N-methyltransferase activity	3.0539218951403	bayes_pls_golite062009
protein methyltransferase activity	3.01384869242051	bayes_pls_golite062009
transferase activity	2.22303238506686	bayes_pls_golite062009
histone methyltransferase activity	1.90505369820945	bayes_pls_golite062009
rRNA (adenine) methyltransferase activity	1.83964463328968	bayes_pls_golite062009
rRNA (adenine-N6,N6-)-dimethyltransferase activity	1.75675289134467	bayes_pls_golite062009
DNA-methyltransferase activity	1.63765148226572	bayes_pls_golite062009
arginine N-methyltransferase activity	1.6030970825293	bayes_pls_golite062009
protein-arginine N-methyltransferase activity	1.6030970825293	bayes_pls_golite062009
catalytic activity	1.25333584501255	bayes_pls_golite062009
tRNA methyltransferase activity	1.12859857407629	bayes_pls_golite062009
rRNA (guanine) methyltransferase activity	1.10713374933008	bayes_pls_golite062009
histone-arginine N-methyltransferase activity	1.05897361334523	bayes_pls_golite062009
site-specific DNA-methyltransferase (adenine-specific) activity	0.703178429468566	bayes_pls_golite062009
protein-arginine omega-N monomethyltransferase activity	0.639377525568296	bayes_pls_golite062009
protein-arginine omega-N asymmetric methyltransferase activity	0.130104080746388	bayes_pls_golite062009
histone methyltransferase activity (H4-R3 specific)	0.130042730841119	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: