YRC Public Data Repository - Protein Structure Prediction

Protein:	MTAP_GEOSL
Organism:	Geobacter sulfurreducens PCA
Length:	286 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MTAP_GEOSL.

Description	E-value	Query Range	Subject Range
gi\|57225169, gi\|... - gi\|57234721\|ref\|YP_181261.1\| methylthioadenosine phosphorylase [Dehalococcoides ethenogenes 195], gi...	321.0	[0..3]	[286..5]
gi\|91201671 - gi\|91201671\|emb\|CAJ74731.1\| strongly similar to 5'-methylthioadenosine phosphorylase [Candidatus Kue...	318.0	[0..5]	[286..6]
gi\|31789447 - gi\|31789447\|gb\|AAP58561.1\| putative 5'-methylthioadenosine phosphorylase [uncultured Acidobacteria b...	318.0	[0..2]	[285..3]
gi\|56750628, gi\|... - gi\|56750628\|ref\|YP_171329.1\| 5'-methylthioadenosine phosphorylase [Synechococcus elongatus PCC 6301]... gi\|46129569, gi\|... - gi\|81299732\|ref\|YP_399940.1\| 5'-methylthioadenosine phosphorylase [Synechococcus elongatus PCC 7942]...	317.0	[0..2]	[285..3]
gi\|67857056, gi\|... - gi\|67920939\|ref\|ZP_00514458.1\| Methylthioadenosine phosphorylase [Crocosphaera watsonii WH 8501], gi...	316.0	[0..2]	[286..4]
gi\|73748358, gi\|... - gi\|73748358\|ref\|YP_307597.1\| methylthioadenosine phosphorylase [Dehalococcoides sp. CBDB1], gi\|73660...	316.0	[0..3]	[286..5]
gi\|78195135, gi\|... - gi\|78223880\|ref\|YP_385627.1\| methylthioadenosine phosphorylase [Geobacter metallireducens GS-15], gi...	315.0	[0..5]	[286..6]
gi\|77919617, gi\|... - gi\|77919617\|ref\|YP_357432.1\| methylthioadenosine phosphorylase [Pelobacter carbinolicus DSM 2380], g...	314.0	[0..2]	[286..3]
gi\|75907875, gi\|... - gi\|75907875\|ref\|YP_322171.1\| 5'-methylthioadenosine phosphorylase [Anabaena variabilis ATCC 29413], ...	313.0	[0..3]	[286..4]
gi\|88933389, gi\|... - gi\|88933389\|ref\|ZP_01139067.1\| Methylthioadenosine phosphorylase [Dehalococcoides sp. BAV1], gi\|8891...	312.0	[0..3]	[286..5]

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Predicted Domain #1

Region A:
Residues: [1-286]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEQVIGVIGG SGLYEMEGLQ DVRSIVVETP FGAPSDEFVT GVLDGVRMVF LPRHGRGHRL  60
   61 LPTEVNYRAN IYGMKKLGVT RIISVSAVGS MREEIVPGHI VIPDQFIDRT NATRANTFFG 120
  121 NGVVAHIQFA DPVCADLSAD LYAAAQEAGA TVHRGGTYIC MEGPAFSTRA ESNLYRSFGV 180
  181 SVIGMTNIPE AKLAREAEIC YGVIALATDY DCWHESHDDV SVDAIIAIIK QNVAMAKSII 240
  241 RNAVRRIDRE RNCPCASALR YAIITDKAAI PAETKERLDL IIGSYV

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	80.69897
Match:	1cb0A
Description:	5'-deoxy-5'-methylthioadenosine phosphorylase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
S-methyl-5-thioadenosine phosphorylase activity	3.89303327575747	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	3.66765825367784	bayes_pls_golite062009
transferase activity	2.19158134892504	bayes_pls_golite062009
catalytic activity	2.18268586151113	bayes_pls_golite062009
transferase activity, transferring pentosyl groups	2.01261001022129	bayes_pls_golite062009
purine binding	0.370193176405818	bayes_pls_golite062009
protein binding	0.295595362082672	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: