YRC Public Data Repository - Protein Structure Prediction

Protein:	RNC_COXBU
Organism:	Coxiella burnetii RSA 493
Length:	233 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for RNC_COXBU.

Description	E-value	Query Range	Subject Range
gi\|62128779, gi\|... - gi\|62181146\|ref\|YP_217563.1\| ribonuclease III [Salmonella enterica subsp. enterica serovar Choleraes...	251.0	[0..4]	[223..25]
RNC_COXBN - Ribonuclease 3 OS=Coxiella burnetii (strain Dugway 5J108-111) GN=rnc PE=3 SV=1 gi\|154707005, gi... - gi\|94491847\|ref\|ZP_01299057.1\| hypothetical protein CburD_01001245 [Coxiella burnetii Dugway 7E9-12]... gi\|165916991, gi... - gi\|165919331\|ref\|ZP_02219417.1\| ribonuclease III [Coxiella burnetii RSA 334], gi\|165916991\|gb\|EDR355...	247.0	[0..1]	[233..1]
RNC_SALCH - Ribonuclease 3 OS=Salmonella choleraesuis GN=rnc PE=3 SV=2 RNC_SALCH - Ribonuclease 3 OS=Salmonella choleraesuis (strain SC-B67) GN=rnc PE=3 SV=2 RNC_SALCH - Ribonuclease 3 OS=Salmonella choleraesuis GN=rnc PE=3 SV=2	246.0	[0..4]	[223..6]
gi\|439871, gi\|21... - gi\|439871\|gb\|AAA69690.1\| ribonuclease [Coxiella burnetii], pir\|\|S60767 ribonuclease III - Coxiella b...	244.0	[0..1]	[233..1]
gi\|91227852, gi\|... - gi\|91227852\|ref\|ZP_01262025.1\| ribonuclease III [Vibrio alginolyticus 12G01], gi\|91188362\|gb\|EAS7465...	241.0	[0..1]	[223..1]
RNC_PASMU - Ribonuclease 3 OS=Pasteurella multocida (strain Pm70) GN=rnc PE=3 SV=1 RNC_PASMU - Ribonuclease 3 OS=Pasteurella multocida GN=rnc PE=3 SV=1	240.0	[0..2]	[221..3]
gi\|194538394, gi... - gi\|75854070\|ref\|ZP_00761790.1\| COG0571: dsRNA-specific ribonuclease [Vibrio sp. Ex25], gi\|254230524\|...	240.0	[0..1]	[223..1]
gi\|153839958, gi... - gi\|153839958\|ref\|ZP_01992625.1\| ribonuclease III [Vibrio parahaemolyticus AQ3810], gi\|149746517\|gb\|E... RNC_VIBPA - Ribonuclease 3 OS=Vibrio parahaemolyticus GN=rnc PE=3 SV=1 RNC_VIBPA - Ribonuclease 3 OS=Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 2210633) GN=rnc PE=3 SV=1	240.0	[0..1]	[223..1]
RNC_SHEAM - Ribonuclease 3 OS=Shewanella amazonensis (strain ATCC BAA-1098 / SB2B) GN=rnc PE=3 SV=1	239.0	[0..1]	[222..4]
gi\|197335272, gi... - gi\|197335272\|ref\|YP_002156886.1\| ribonuclease III [Vibrio fischeri MJ11], gi\|197316762\|gb\|ACH66209.1... RNC_VIBF1 - Ribonuclease 3 OS=Vibrio fischeri (strain ATCC 700601 / ES114) GN=rnc PE=3 SV=1	239.0	[0..2]	[221..3]

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Predicted Domain #1

Region A:
Residues: [1-233]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNHLNKLMER LGHQFNNLEL LKIALTHCSS GADNNERLEF LGDSVLGFII ASELYQRRPQ  60
   61 AREGDLSRMR ASMVNGDELA QMSTKLGINE YLQLGVGEQK SGGKRRRSIL ADALEAIVGA 120
  121 IYIDAGLETC RRCVLNWYGE RVDDLSKLSP KKDAKSLLQE WLQARRLPLP TYEVKITGEA 180
  181 HAQTFTVNCY VKGLPHKTEG VNTTRRRAEQ IAAKRFLELL DDGKGDGITE RDQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	51.69897
Match:	1o0wA
Description:	RNase III endonuclease catalytic domain; RNase III, C-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
RNA binding	2.103878681691	bayes_pls_golite062009
endoribonuclease activity	2.02847548000256	bayes_pls_golite062009
endonuclease activity	1.52328576888271	bayes_pls_golite062009
binding	1.36306903445995	bayes_pls_golite062009
nucleic acid binding	1.33734225890407	bayes_pls_golite062009
double-stranded RNA binding	0.80785216315429	bayes_pls_golite062009
catalytic activity	0.328884095744829	bayes_pls_golite062009
protein binding	0.018276859224266	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: