YRC Public Data Repository - Protein Structure Prediction

Protein:	PYRH_COXBU
Organism:	Coxiella burnetii RSA 493
Length:	243 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PYRH_COXBU.

Description	E-value	Query Range	Subject Range
gi\|89048834, gi\|... - gi\|89075418\|ref\|ZP_01161835.1\| uridylate kinase [Photobacterium sp. SKA34], gi\|89048834\|gb\|EAR54404.... gi\|88813751, gi\|... - gi\|88813751\|ref\|ZP_01128969.1\| uridylate kinase [Nitrococcus mobilis Nb-231], gi\|88788995\|gb\|EAR2014...	238.0	[0..1]	[241..1]
gi\|90437851, gi\|... - gi\|90580973\|ref\|ZP_01236774.1\| uridylate kinase [Vibrio angustum S14], gi\|90437851\|gb\|EAS63041.1\| ur...	237.0	[0..1]	[240..1]
PYRH_PSEA6 - Uridylate kinase OS=Pseudoalteromonas atlantica (strain T6c / ATCC BAA-1087) GN=pyrH PE=3 SV=1	235.0	[0..1]	[243..1]
PYRH_COLP3 - Uridylate kinase OS=Colwellia psychrerythraea (strain 34H / ATCC BAA-681) GN=pyrH PE=3 SV=1	233.0	[0..1]	[240..1]
gi\|238714199, gi... - gi\|77957691\|ref\|ZP_00821740.1\| COG0528: Uridylate kinase [Yersinia bercovieri ATCC 43970], gi\|238784... gi\|238727861, gi... - gi\|77977746\|ref\|ZP_00833187.1\| COG0528: Uridylate kinase [Yersinia intermedia ATCC 29909], gi\|238792...	233.0	[0..1]	[242..1]
gi\|77963173, gi\|... - gi\|77963173\|ref\|ZP_00826985.1\| COG0528: Uridylate kinase [Yersinia mollaretii ATCC 43969], gi\|238796...	232.0	[0..1]	[242..1]
gi\|238710316, gi... - gi\|238751449\|ref\|ZP_04612941.1\| Uridylate kinase [Yersinia rohdei ATCC 43380], gi\|238710316\|gb\|EEQ02... gi\|238787233, gi... - gi\|77972712\|ref\|ZP_00828271.1\| COG0528: Uridylate kinase [Yersinia frederiksenii ATCC 33641], gi\|238...	232.0	[0..1]	[242..1]
gi\|90413531, gi\|... - gi\|90413531\|ref\|ZP_01221522.1\| uridylate kinase [Photobacterium profundum 3TCK], gi\|90325463\|gb\|EAS4...	232.0	[0..1]	[240..1]
PYRH_SHELP - Uridylate kinase OS=Shewanella loihica (strain ATCC BAA-1088 / PV-4) GN=pyrH PE=3 SV=1	231.0	[0..1]	[240..1]
PYRH_PHOPR - Uridylate kinase OS=Photobacterium profundum GN=pyrH PE=3 SV=1 PYRH_PHOPR - Uridylate kinase OS=Photobacterium profundum (strain SS9) GN=pyrH PE=3 SV=1	231.0	[0..1]	[240..1]

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Predicted Domain #1

Region A:
Residues: [1-243]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTNGPQPLYR RVLLKMSGEA LMGKGLHAID PNVLDRMAKD VTQVYQLGVQ IAIVIGGGNF  60
   61 FRGAALQAAG INRITGDYMG MLATLMNALA LRDAFERSNL PVRILSAIPM TGVADAFHRR 120
  121 KAIHHLQQGR VVIFAAGTGN PLVTTDSAAS LRGIEINADV VLKATNVDGV YSDDPAKNPQ 180
  181 AKLYKHLSYQ EALKKELAVM DLAAFCQCRD YNMPLRVFNI NKPGALLSVI MNQEEGTLVD 240
  241 QGQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	59.30103
Match:	2bneA
Description:	The structure of E. coli UMP kinase in complex with UMP
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
kinase activity	5.43826659128409	bayes_pls_golite062009
nucleobase, nucleoside, nucleotide kinase activity	4.76215533422168	bayes_pls_golite062009
nucleotide kinase activity	4.36245911991838	bayes_pls_golite062009
phosphotransferase activity, phosphate group as acceptor	4.17538459617947	bayes_pls_golite062009
uridylate kinase activity	3.54453921304057	bayes_pls_golite062009
catalytic activity	3.20382750184555	bayes_pls_golite062009
transferase activity	2.54481238004476	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	1.89315414622708	bayes_pls_golite062009
phosphotransferase activity, carboxyl group as acceptor	1.02979719559565	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: