YRC Public Data Repository - Protein Structure Prediction

Protein:	LOLA_COXBU
Organism:	Coxiella burnetii RSA 493
Length:	211 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for LOLA_COXBU.

Description	E-value	Query Range	Subject Range
LOLA_DECAR - Outer-membrane lipoprotein carrier protein OS=Dechloromonas aromatica (strain RCB) GN=lolA PE=3 SV=1	203.0	[0..2]	[209..1]
gi\|1787118, gi\|1... - gi\|1787118\|gb\|AAC73977.1\| chaperone for lipoproteins [Escherichia coli K12], dbj\|BAA35623.1\| Outer m... gi\|12514053, gi\|... - gi\|15800754\|ref\|NP_286768.1\| outer-membrane lipoprotein carrier protein [Escherichia coli O157:H7 ED... gi\|227838894, gi... - gi\|227884142\|ref\|ZP_04001947.1\| outer-membrane lipoprotein carrier protein [Escherichia coli 83972],... gi\|226898329, gi... - gi\|237707119\|ref\|ZP_04537600.1\| periplasmic protein [Escherichia sp. 3_2_53FAA], gi\|226898329\|gb\|EEH... gi\|242376706, gi... - gi\|251784433\|ref\|YP_002998737.1\| hypothetical protein B21_00902 [Escherichia coli BL21], gi\|24237670... gi\|254161005, gi... - gi\|254161005\|ref\|YP_003044113.1\| outer-membrane lipoprotein carrier protein precursor [Escherichia c... gi\|253977120, gi... - gi\|254287813\|ref\|YP_003053561.1\| outer-membrane lipoprotein carrier protein precursor [Escherichia c... gi\|209911399, gi... - gi\|209918140\|ref\|YP_002292224.1\| outer-membrane lipoprotein carrier protein [Escherichia coli SE11],... gi\|218548413, gi... - gi\|218548413\|ref\|YP_002382204.1\| outer-membrane lipoprotein carrier protein [Escherichia fergusonii ... gi\|215264093, gi... - gi\|215486021\|ref\|YP_002328452.1\| outer-membrane lipoprotein carrier protein [Escherichia coli O127:H... gi\|218364568, gi... - gi\|218557799\|ref\|YP_002390712.1\| outer-membrane lipoprotein carrier protein [Escherichia coli S88], ... gi\|218553477, gi... - gi\|218553477\|ref\|YP_002386390.1\| outer-membrane lipoprotein carrier protein [Escherichia coli IAI1],... gi\|209775044, gi... - gi\|974728\|dbj\|BAA08390.1\| lipoprotein carrier protein precursor [Escherichia coli], gi\|25348772\|pir\|... gi\|24112266, gi\|... - gi\|24112266\|ref\|NP_706776.1\| outer-membrane lipoprotein carrier protein [Shigella flexneri 2a str. 3... gi\|26107317, gi\|... - gi\|26246917\|ref\|NP_752957.1\| outer-membrane lipoprotein carrier protein [Escherichia coli CFT073], g... gi\|30062378, gi\|... - gi\|30062378\|ref\|NP_836549.1\| outer-membrane lipoprotein carrier protein [Shigella flexneri 2a str. 2... gi\|13360435, gi\|... - gi\|15830230\|ref\|NP_309003.1\| outer-membrane lipoprotein carrier protein precursor [Escherichia coli ... gi\|75512044 - gi\|75512044\|ref\|ZP_00734629.1\| COG2834: Outer membrane lipoprotein-sorting protein [Escherichia coli... gi\|75257394 - gi\|75257394\|ref\|ZP_00728910.1\| COG2834: Outer membrane lipoprotein-sorting protein [Escherichia coli... gi\|75240968 - gi\|75240968\|ref\|ZP_00724857.1\| COG2834: Outer membrane lipoprotein-sorting protein [Escherichia coli... gi\|75234426 - gi\|75234426\|ref\|ZP_00718787.1\| COG2834: Outer membrane lipoprotein-sorting protein [Escherichia coli... gi\|1651413, gi\|8... - gi\|89107741\|ref\|AP_001521.1\| chaperone for lipoproteins [Escherichia coli str. K-12 substr. W3110], ... gi\|117623075, gi... - gi\|117623075\|ref\|YP_851988.1\| outer-membrane lipoprotein carrier protein [Escherichia coli APEC O1],... gi\|82543377, gi\|... - gi\|82543377\|ref\|YP_407324.1\| outer-membrane lipoprotein carrier protein [Shigella boydii Sb227], gi\|... gi\|82777587, gi\|... - gi\|82777587\|ref\|YP_403936.1\| outer-membrane lipoprotein carrier protein [Shigella dysenteriae Sd197]... gi\|74311449, gi\|... - gi\|74311449\|ref\|YP_309868.1\| outer-membrane lipoprotein carrier protein [Shigella sonnei Ss046], gi\|... gi\|75178305 - gi\|75178305\|ref\|ZP_00698359.1\| COG2834: Outer membrane lipoprotein-sorting protein [Shigella boydii ... gi\|218694364, gi... - gi\|218694364\|ref\|YP_002402031.1\| outer-membrane lipoprotein carrier protein [Escherichia coli 55989]... gi\|83585834 - gi\|83585834\|ref\|ZP_00924474.1\| COG2834: Outer membrane lipoprotein-sorting protein [Escherichia coli... gi\|218688679, gi... - gi\|218688679\|ref\|YP_002396891.1\| outer-membrane lipoprotein carrier protein [Escherichia coli ED1a],... gi\|218704320, gi... - gi\|218704320\|ref\|YP_002411839.1\| outer-membrane lipoprotein carrier protein [Escherichia coli UMN026... gi\|218700591, gi... - gi\|218700591\|ref\|YP_002408220.1\| outer-membrane lipoprotein carrier protein [Escherichia coli IAI39]... gi\|75229259 - gi\|75229259\|ref\|ZP_00715824.1\| COG2834: Outer membrane lipoprotein-sorting protein [Escherichia coli... gi\|91071510, gi\|... - gi\|91209936\|ref\|YP_539922.1\| outer-membrane lipoprotein carrier protein [Escherichia coli UTI89], gi... gi\|75210420 - gi\|75210420\|ref\|ZP_00710576.1\| COG2834: Outer membrane lipoprotein-sorting protein [Escherichia coli... gi\|13360435, gi\|... - gi\|15830230\|ref\|NP_309003.1\| outer-membrane lipoprotein carrier protein [Escherichia coli O157:H7 st... gi\|75195079 - gi\|75195079\|ref\|ZP_00705149.1\| COG2834: Outer membrane lipoprotein-sorting protein [Escherichia coli... gi\|75189931 - gi\|75189931\|ref\|ZP_00703198.1\| COG2834: Outer membrane lipoprotein-sorting protein [Escherichia coli...	199.0	[0..3]	[211..1]
gi\|67155736, gi\|... - gi\|67155736\|ref\|ZP_00417363.1\| Outer membrane lipoprotein carrier protein LolA [Azotobacter vineland... LOLA_AZOVD - Outer-membrane lipoprotein carrier protein OS=Azotobacter vinelandii (strain DJ / ATCC BAA-1303) GN=...	198.0	[0..4]	[211..1]
LOLA_ECO5E - Outer-membrane lipoprotein carrier protein OS=Escherichia coli O157:H7 (strain EC4115 / EHEC) GN=lol... gi\|217320458, gi... - gi\|217324237\|ref\|ZP_03440321.1\| outer membrane lipoprotein carrier protein LolA [Escherichia coli O1... EG12684 - lipoprotein chaperone / Periplasmic protein responsible for sorting and transporting lipoproteins to... gi\|194438716, gi... - gi\|194438716\|ref\|ZP_03070803.1\| outer membrane lipoprotein carrier protein LolA [Escherichia coli 10... gi\|254792091, gi... - gi\|254792091\|ref\|YP_003076928.1\| chaperone for lipoproteins [Escherichia coli O157:H7 str. TW14359],... gi\|195939554 - gi\|195939554\|ref\|ZP_03084936.1\| outer-membrane lipoprotein carrier protein [Escherichia coli O157:H7... gi\|208732084, gi... - gi\|208815436\|ref\|ZP_03256615.1\| outer membrane lipoprotein carrier protein LolA [Escherichia coli O1... LOLA_ECOBW - Outer-membrane lipoprotein carrier protein OS=Escherichia coli (strain K12 / MC4100 / BW2952) GN=lol... gi\|208737755, gi... - gi\|208822270\|ref\|ZP_03262589.1\| outer membrane lipoprotein carrier protein LolA [Escherichia coli O1... gi\|253774080, gi... - gi\|253774080\|ref\|YP_003036911.1\| outer membrane lipoprotein carrier protein LolA [Escherichia coli B... gi\|190907673, gi... - gi\|191172146\|ref\|ZP_03033690.1\| outer membrane lipoprotein carrier protein LolA [Escherichia coli F1... gi\|193064624, gi... - gi\|193064624\|ref\|ZP_03045703.1\| outer membrane lipoprotein carrier protein LolA [Escherichia coli E2... gi\|193070750, gi... - gi\|193070750\|ref\|ZP_03051685.1\| outer membrane lipoprotein carrier protein LolA [Escherichia coli E1... gi\|194413574, gi... - gi\|194428359\|ref\|ZP_03060900.1\| outer membrane lipoprotein carrier protein LolA [Escherichia coli B1... gi\|188491116, gi... - gi\|188495917\|ref\|ZP_03003187.1\| outer membrane lipoprotein carrier protein LolA [Escherichia coli 53... gi\|188998920, gi... - gi\|189010699\|ref\|ZP_02808808.2\| outer membrane lipoprotein carrier protein LolA [Escherichia coli O1... gi\|124498246, gi... - gi\|124531984\|ref\|ZP_01702043.1\| outer membrane lipoprotein carrier protein LolA [Escherichia coli B]... gi\|189361168, gi... - gi\|189403356\|ref\|ZP_02794891.2\| outer membrane lipoprotein carrier protein LolA [Escherichia coli O1... gi\|190902378, gi... - gi\|191167617\|ref\|ZP_03029428.1\| outer membrane lipoprotein carrier protein LolA [Escherichia coli B7... LOLA_ECOLC - Outer-membrane lipoprotein carrier protein OS=Escherichia coli (strain ATCC 8739 / DSM 1576 / Crooks... EG12684 - lipoprotein chaperone / Periplasmic protein responsible for sorting and transporting lipoproteins to... LOLA_SHIF8 - Outer-membrane lipoprotein carrier protein OS=Shigella flexneri serotype 5b (strain 8401) GN=lolA PE... LOLA_ECOLI - Outer-membrane lipoprotein carrier protein precursor (P20) - Escherichia coli LOLA_ECO57 - Outer-membrane lipoprotein carrier protein OS=Escherichia coli O157:H7 GN=lolA PE=3 SV=1 LOLA_ECOL6 - Outer-membrane lipoprotein carrier protein OS=Escherichia coli O6 GN=lolA PE=3 SV=1 LOLA_ECOSM - Outer-membrane lipoprotein carrier protein OS=Escherichia coli (strain SMS-3-5 / SECEC) GN=lolA PE=3... LOLA_SHIB3 - Outer-membrane lipoprotein carrier protein OS=Shigella boydii serotype 18 (strain CDC 3083-94 / BS51... gi\|187768383, gi... - gi\|187776223\|ref\|ZP_02801265.2\| outer membrane lipoprotein carrier protein LolA [Escherichia coli O1... gi\|188013949, gi... - gi\|188025258\|ref\|ZP_02777149.2\| outer membrane lipoprotein carrier protein LolA [Escherichia coli O1... gi\|168756982, gi... - gi\|189355932\|gb\|EDU74351.1\| outer membrane lipoprotein carrier protein LolA [Escherichia coli O157:H... gi\|189366819, gi... - gi\|189366819\|gb\|EDU85235.1\| outer membrane lipoprotein carrier protein LolA [Escherichia coli O157:H... gi\|168787319, gi... - gi\|189372639\|gb\|EDU91055.1\| outer membrane lipoprotein carrier protein LolA [Escherichia coli O157:H... LOLA_ECODH - Outer-membrane lipoprotein carrier protein OS=Escherichia coli (strain K12 / DH10B) GN=lolA PE=3 SV=... LOLA_SHIFL - Outer-membrane lipoprotein carrier protein OS=Shigella flexneri GN=lolA PE=3 SV=1 LOLA_ECOHS - Outer-membrane lipoprotein carrier protein OS=Escherichia coli O9:H4 (strain HS) GN=lolA PE=3 SV=1 LOLA_ECOL6 - Outer-membrane lipoprotein carrier protein OS=Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / ... LOLA_ECO24 - Outer-membrane lipoprotein carrier protein OS=Escherichia coli O139:H28 (strain E24377A / ETEC) GN=l...	197.0	[0..4]	[211..1]
gi\|205352169, gi... - gi\|205352169\|ref\|YP_002225970.1\| outer-membrane lipoprotein carrier protein [Salmonella enterica sub... gi\|206708156, gi... - gi\|207856353\|ref\|YP_002243004.1\| outer-membrane lipoprotein carrier protein [Salmonella enterica sub... gi\|16764322, gi\|... - gi\|16764322\|ref\|NP_459937.1\| outer-membrane lipoprotein carrier protein [Salmonella typhimurium LT2]... lcl\|NC_016856.1_... - [gene=lolA] [protein=outer-membrane lipoprotein carrier protein] [protein_id=YP_005236675.1] [locati...	196.0	[0..2]	[211..1]
LOLA_THIDA - Outer-membrane lipoprotein carrier protein OS=Thiobacillus denitrificans (strain ATCC 25259) GN=lolA...	195.0	[0..4]	[209..1]
gi\|213428593 - gi\|213428593\|ref\|ZP_03361343.1\| outer-membrane lipoprotein carrier protein [Salmonella enterica subs... gi\|25348776, gi\|... - gi\|25348776\|pir\|\|AG0611 outer membrane lipoprotein carrier protein precursor STY0959 [imported] - Sa... gi\|213418911 - gi\|213418911\|ref\|ZP_03351977.1\| outer-membrane lipoprotein carrier protein [Salmonella enterica subs... gi\|214003463 - gi\|214003463\|ref\|ZP_03414198.1\| outer-membrane lipoprotein carrier protein [Salmonella enterica subs... gi\|213981709 - gi\|213981709\|ref\|ZP_03408968.1\| outer-membrane lipoprotein carrier protein [Salmonella enterica subs... gi\|29138025, gi\|... - gi\|29142395\|ref\|NP_805737.1\| outer-membrane lipoprotein carrier protein [Salmonella enterica subsp. ... gi\|213650896 - gi\|213650896\|ref\|ZP_03380949.1\| outer-membrane lipoprotein carrier protein [Salmonella enterica subs... gi\|16759832 - gi\|16759832\|ref\|NP_455449.1\| outer-membrane lipoprotein carrier protein [Salmonella enterica subsp. ... gi\|213581060 - gi\|213581060\|ref\|ZP_03362886.1\| outer-membrane lipoprotein carrier protein [Salmonella enterica subs...	195.0	[0..2]	[211..1]
gi\|110342683, gi... - gi\|110641091\|ref\|YP_668821.1\| outer-membrane lipoprotein carrier protein [Escherichia coli 536], gi\|...	195.0	[0..3]	[211..1]
gi\|56413987, gi\|... - gi\|56413987\|ref\|YP_151062.1\| outer-membrane lipoprotein carrier protein [Salmonella enterica subsp. ...	194.0	[0..9]	[211..1]
gi\|62179485, gi\|... - gi\|62179485\|ref\|YP_215902.1\| outer-membrane lipoprotein carrier protein [Salmonella enterica subsp. ...	193.0	[0..2]	[211..1]

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Predicted Domain #1

Region A:
Residues: [1-211]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNTIKILIGL LGIFLFSLSG IVSAQSDATT QLSQLLSNFR TYQAKFNQIT FDGQDRVIQQ  60
   61 SHGRVMIMRP GRFRWETDSP TKQIIITNGK TLWVYDVDLS QATQQPLAQK TNINPASLLS 120
  121 GSVKDLKQKF TITISPTPDA ATFQLVPNLG KSLNFNWIRL KFSKKQLTEM TVLNNLDERS 180
  181 IFQFSQIKVN APLSSTLFEF KPSRGIDVVK Q

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	46.522879
Match:	1iwlA
Description:	Outer-membrane lipoproteins carrier protein LolA
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
protein transporter activity	2.94733677676109	bayes_pls_golite062009
protein transmembrane transporter activity	2.80163572604854	bayes_pls_golite062009
transporter activity	1.94557075462337	bayes_pls_golite062009
transmembrane transporter activity	1.8285077384404	bayes_pls_golite062009
substrate-specific transporter activity	1.57976971135135	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	1.4723961195197	bayes_pls_golite062009
protein binding	1.38954552030231	bayes_pls_golite062009
binding	1.0696248685847	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: