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View Structure Prediction Details

Protein: gi|29654099, gi|...
Organism: Coxiella burnetii RSA 493
Length: 228 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|29654099, gi|....

Description E-value Query
Range
Subject
Range
GUAA_SALRD - GMP synthase [glutamine-hydrolyzing] OS=Salinibacter ruber (strain DSM 13855 / M31) GN=guaA PE=3 SV=...
194.0 [0..2] [218..4]
GUAA_BACLD - GMP synthase [glutamine-hydrolyzing] OS=Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 250...
189.0 [0..3] [218..9]
GUAA_LISIN - GMP synthase [glutamine-hydrolyzing] OS=Listeria innocua GN=guaA PE=3 SV=1
GUAA_LISIN - GMP synthase [glutamine-hydrolyzing] OS=Listeria innocua serovar 6a (strain CLIP 11262) GN=guaA PE=3...
189.0 [0..2] [218..13]
gi|88935980, gi|... - gi|88935980|ref|ZP_01141601.1| GMP synthase, C-terminal:GMP synthase, N-terminal [Geobacter uraniumr...
189.0 [0..2] [218..9]
gi|87289437, gi|... - gi|87307823|ref|ZP_01089966.1| GMP synthase [Blastopirellula marina DSM 3645], gi|87289437|gb|EAQ813...
189.0 [0..2] [218..21]
GUAA_CLOTH - GMP synthase [glutamine-hydrolyzing] OS=Clostridium thermocellum (strain ATCC 27405 / DSM 1237 / NBR...
189.0 [0..3] [218..6]
gi|238834567, gi... - gi|238852873|ref|ZP_04643278.1| GMP synthase [Lactobacillus gasseri 202-4], gi|238834567|gb|EEQ26799...
GUAA_LACGA - GMP synthase [glutamine-hydrolyzing] OS=Lactobacillus gasseri (strain ATCC 33323 / DSM 20243 / JCM 1...
gi|23003310 - gi|23003310|ref|ZP_00046975.1| COG0519: GMP synthase, PP-ATPase domain/subunit [Lactobacillus gasser...
gi|226820045 - gi|226820045|ref|ZP_03809164.1| GMP synthase [Lactobacillus gasseri MV-22]
187.0 [0..2] [218..11]
gi|221089178, gi... - gi|221089178|ref|ZP_03558700.1| GMP synthase, large subunit [Geobacillus sp. Y412MC61], gi|220706876...
GUAA_GEOKA - GMP synthase [glutamine-hydrolyzing] OS=Geobacillus kaustophilus GN=guaA PE=3 SV=1
gi|229328416, gi... - gi|229500698|ref|ZP_04394346.1| GMP synthase, large subunit [Geobacillus sp. Y412MC52], gi|229328416...
GUAA_GEOKA - GMP synthase [glutamine-hydrolyzing] OS=Geobacillus kaustophilus (strain HTA426) GN=guaA PE=3 SV=1
187.0 [0..3] [218..6]
gi|228937552, gi... - gi|228937552|ref|ZP_04100193.1| GMP synthase, large subunit [Bacillus thuringiensis serovar berliner...
gi|228860640, gi... - gi|228898997|ref|ZP_04063272.1| GMP synthase, large subunit [Bacillus thuringiensis IBL 4222], gi|22...
gi|228977009, gi... - gi|228977009|ref|ZP_04137416.1| GMP synthase, large subunit [Bacillus thuringiensis Bt407], gi|22878...
gi|74490054, gi|... - gi|75762461|ref|ZP_00742326.1| GMP synthase (glutamine-hydrolyzing) [Bacillus thuringiensis serovar ...
gi|228789288, gi... - gi|228970439|ref|ZP_04131093.1| GMP synthase, large subunit [Bacillus thuringiensis serovar thuringi...
187.0 [0..3] [218..11]
GUAA_BACCR - GMP synthase [glutamine-hydrolyzing] OS=Bacillus cereus (strain ATCC 14579 / DSM 31 / JCM 2152 / NBR...
gi|229125762, gi... - gi|229125762|ref|ZP_04254790.1| GMP synthase, large subunit [Bacillus cereus BDRD-Cer4], gi|22865770...
187.0 [0..3] [218..11]

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Predicted Domain #1
Region A:
Residues: [1-228]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKIHYIMHAP FEKLSAIEVW ATQKSYDLSG THVYKGEKLP RALNFDCLIL MGGPQSPFKT  60
   61 DKYPYLLDEI QFVKKALAGN KKILGICLGA QLIAEALGAK TLHSPYKEIG IYPIQTLPEA 120
  121 TDDPFFSKLP KSFDVMHWHN DMPGIPKDVV LLAKGEGCPH QAFRYGDRVY GFQFHMELTL 180
  181 SVIEEMIEKY RGDLEPGKFV RTKEEMLHSN YNEVNAKMFT FLDYLEGV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 45.0
Match: 1gpmA
Description: GMP synthetase; GMP synthetase, central domain; GMP synthetase C-terminal dimerisation domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 1.67435536171189 bayes_pls_golite062009
ligase activity 0.0238422970481118 bayes_pls_golite062009
carbon-nitrogen ligase activity, with glutamine as amido-N-donor 5.21123699382953E-4 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle