YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|29654069, gi\|...
Organism:	Coxiella burnetii RSA 493
Length:	282 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

[What does the above image mean?]

[Show Ginzu Version Information]

Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|29654069, gi|....

Description	E-value	Query Range	Subject Range
DEOD_THETN - Purine nucleoside phosphorylase deoD-type OS=Thermoanaerobacter tengcongensis GN=deoD PE=3 SV=1 DEOD_CALS4 - Purine nucleoside phosphorylase DeoD-type OS=Caldanaerobacter subterraneus subsp. tengcongensis (str...	203.0	[0..7]	[265..1]
gi\|71041660, gi\|... - gi\|71041676\|pdb\|1U1G\|F Chain F, Structure Of E. Coli Uridine Phosphorylase Complexed To 5- (M-(Benzy...	203.0	[0..2]	[272..3]
gi\|187731170, gi... - gi\|75177797\|ref\|ZP_00697862.1\| COG2820: Uridine phosphorylase [Shigella boydii BS512], gi\|187731170\|... gi\|157155953, gi... - gi\|75188573\|ref\|ZP_00701840.1\| COG2820: Uridine phosphorylase [Escherichia coli E24377A], gi\|1571559... gi\|13364237, gi\|... - gi\|15834015\|ref\|NP_312788.1\| uridine phosphorylase [Escherichia coli O157:H7], gi\|13364237\|dbj\|BAB38... gi\|75209542, gi\|... - gi\|75209542\|ref\|ZP_00709763.1\| COG2820: Uridine phosphorylase [Escherichia coli B171], gi\|194429224\|... gi\|209753080, gi... - pir\|\|G86070 uridine phosphorylase [imported] - Escherichia coli (strain O157:H7, substrain EDL933),... gi\|75238281, gi\|... - gi\|75238281\|ref\|ZP_00722280.1\| COG2820: Uridine phosphorylase [Escherichia coli E110019], gi\|1930680... gi\|217325150, gi... - gi\|217325150\|ref\|ZP_03441234.1\| uridine phosphorylase [Escherichia coli O157:H7 str. TW14588], gi\|21... gi\|12518708, gi\|... - gi\|15804423\|ref\|NP_290463.1\| uridine phosphorylase [Escherichia coli O157:H7 EDL933], gi\|12518708\|gb... gi\|209921310, gi... - gi\|209921310\|ref\|YP_002295394.1\| uridine phosphorylase [Escherichia coli SE11], gi\|209914569\|dbj\|BAG... gi\|218707464, gi... - gi\|218707464\|ref\|YP_002414983.1\| uridine phosphorylase [Escherichia coli UMN026], gi\|218434561\|emb\|C... gi\|218363166, gi... - gi\|218556397\|ref\|YP_002389311.1\| uridine phosphorylase [Escherichia coli IAI1], gi\|218363166\|emb\|CAR... gi\|254795829, gi... - gi\|254795829\|ref\|YP_003080666.1\| uridine phosphorylase [Escherichia coli O157:H7 str. TW14359], gi\|2... gi\|189376681, gi... - gi\|189376681\|gb\|EDU95097.1\| uridine phosphorylase [Escherichia coli O157:H7 str. EC508], gi\|16880110... gi\|13364237, gi\|... - gi\|15834015\|ref\|NP_312788.1\| uridine phosphorylase [Escherichia coli O157:H7 str. Sakai], gi\|1336423... gi\|189373448, gi... - gi\|189373448\|gb\|EDU91864.1\| uridine phosphorylase [Escherichia coli O157:H7 str. EC869], gi\|16878667... gi\|195938123 - gi\|195938123\|ref\|ZP_03083505.1\| uridine phosphorylase [Escherichia coli O157:H7 str. EC4024] gi\|170022147, gi... - gi\|170022147\|ref\|YP_001727101.1\| uridine phosphorylase [Escherichia coli ATCC 8739], gi\|169757075\|gb... gi\|208811937, gi... - gi\|208811937\|ref\|ZP_03253266.1\| uridine phosphorylase [Escherichia coli O157:H7 str. EC4045], gi\|208... gi\|208806527, gi... - gi\|208806527\|ref\|ZP_03248864.1\| uridine phosphorylase [Escherichia coli O157:H7 str. EC4206], gi\|208... gi\|124530432, gi... - gi\|124530432\|ref\|ZP_01701090.1\| uridine phosphorylase [Escherichia coli B], gi\|124499198\|gb\|EAY46691... gi\|209157215, gi... - gi\|209395815\|ref\|YP_002273350.1\| uridine phosphorylase [Escherichia coli O157:H7 str. EC4115], gi\|20... gi\|208741896, gi... - gi\|208821773\|ref\|ZP_03262093.1\| uridine phosphorylase [Escherichia coli O157:H7 str. EC4042], gi\|208... gi\|75256245, gi\|... - gi\|75256245\|ref\|ZP_00727923.1\| COG2820: Uridine phosphorylase [Escherichia coli E22], gi\|193065675\|r... gi\|75512614, gi\|... - gi\|75512614\|ref\|ZP_00735126.1\| COG2820: Uridine phosphorylase [Escherichia coli 53638], gi\|188492565... gi\|81243136, gi\|... - gi\|82778988\|ref\|YP_405337.1\| uridine phosphorylase [Shigella dysenteriae Sd197], gi\|81243136\|gb\|ABB6... gi\|189359154, gi... - gi\|189359154\|gb\|EDU77573.1\| uridine phosphorylase [Escherichia coli O157:H7 str. EC4401], gi\|1687537... gi\|82546184, gi\|... - gi\|82546184\|ref\|YP_410131.1\| uridine phosphorylase [Shigella boydii Sb227], gi\|81247595\|gb\|ABB68303.... gi\|188015450, gi... - gi\|188015450\|gb\|EDU53572.1\| uridine phosphorylase [Escherichia coli O157:H7 str. EC4113], gi\|1687503... gi\|168768117, gi... - gi\|189362726\|gb\|EDU81145.1\| uridine phosphorylase [Escherichia coli O157:H7 str. EC4486], gi\|1687681... gi\|189365958, gi... - gi\|189365958\|gb\|EDU84374.1\| uridine phosphorylase [Escherichia coli O157:H7 str. EC4501], gi\|1687639... gi\|189001432, gi... - gi\|189001432\|gb\|EDU70418.1\| uridine phosphorylase [Escherichia coli O157:H7 str. EC4076], gi\|1687807... gi\|168775613, gi... - gi\|187768908\|gb\|EDU32752.1\| uridine phosphorylase [Escherichia coli O157:H7 str. EC4196], gi\|1687756...	202.0	[0..3]	[272..1]
gi\|110345763, gi... - gi\|110644171\|ref\|YP_671901.1\| uridine phosphorylase [Escherichia coli 536], gi\|110345763\|gb\|ABG72000... gi\|75237640, gi\|... - gi\|75237640\|ref\|ZP_00721660.1\| COG2820: Uridine phosphorylase [Escherichia coli F11], gi\|191173934\|r... gi\|115515229, gi... - gi\|117626105\|ref\|YP_859428.1\| uridine phosphorylase [Escherichia coli APEC O1], gi\|115515229\|gb\|ABJ0... gi\|194422460, gi... - gi\|83585914\|ref\|ZP_00924553.1\| COG2820: Uridine phosphorylase [Escherichia coli 101-1], gi\|194438656... gi\|237702860, gi... - gi\|237702860\|ref\|ZP_04533341.1\| uridine phosphorylase [Escherichia sp. 3_2_53FAA], gi\|226903031\|gb\|E... gi\|227888561, gi... - gi\|227888561\|ref\|ZP_04006366.1\| uridine phosphorylase [Escherichia coli 83972], gi\|227834400\|gb\|EEJ4... gi\|254163784, gi... - gi\|254163784\|ref\|YP_003046892.1\| uridine phosphorylase [Escherichia coli B str. REL606], gi\|25397568... gi\|162138324 - gi\|162138324\|ref\|YP_543359.2\| uridine phosphorylase [Escherichia coli UTI89] gi\|254290534, gi... - gi\|254290534\|ref\|YP_003056282.1\| uridine phosphorylase [Escherichia coli BL21(DE3)], gi\|253979841\|gb... gi\|170521506, gi... - gi\|170683788\|ref\|YP_001746159.1\| uridine phosphorylase [Escherichia coli SMS-3-5], gi\|170521506\|gb\|A... gi\|218367677, gi... - gi\|218560908\|ref\|YP_002393821.1\| uridine phosphorylase [Escherichia coli S88], gi\|218367677\|emb\|CAR0...	201.0	[0..3]	[274..1]
gi\|73857821, gi\|... - gi\|74314344\|ref\|YP_312763.1\| uridine phosphorylase [Shigella sonnei Ss046], gi\|73857821\|gb\|AAZ90528....	201.0	[0..3]	[272..1]
gi\|83569333, gi\|... - gi\|83569333\|ref\|ZP_00920788.1\| COG2820: Uridine phosphorylase [Shigella dysenteriae 1012], gi\|194434...	200.0	[0..3]	[272..1]
gi\|110617025, gi... - gi\|110807477\|ref\|YP_690997.1\| uridine phosphorylase [Shigella flexneri 5 str. 8401], gi\|110617025\|gb... gi\|56384000, gi\|... - gi\|56480449\|ref\|NP_709637.2\| uridine phosphorylase [Shigella flexneri 2a str. 301], gi\|56384000\|gb\|A... gi\|30043132, gi\|... - gi\|30064872\|ref\|NP_839043.1\| uridine phosphorylase [Shigella flexneri 2a str. 2457T], gi\|30043132\|gb...	200.0	[0..3]	[272..1]
UDP_ECOLI - Uridine phosphorylase (EC 2.4.2.3) (UrdPase) (UPase) - Escherichia coli gi\|169891146, gi... - gi\|170083311\|ref\|YP_001732631.1\| uridine phosphorylase [Escherichia coli str. K-12 substr. DH10B], g... EG11045 - uridine phosphorylase / Uridine phosphorylase gi\|157163307, gi... - gi\|75197714\|ref\|ZP_00707784.1\| COG2820: Uridine phosphorylase [Escherichia coli HS], gi\|157163307\|re... gi\|218354284, gi... - gi\|218697552\|ref\|YP_002405219.1\| uridine phosphorylase [Escherichia coli 55989], gi\|218354284\|emb\|CA... gi\|238902906, gi... - gi\|238902906\|ref\|YP_002928702.1\| uridine phosphorylase [Escherichia coli BW2952], gi\|238863771\|gb\|AC... gi\|75230792, gi\|... - gi\|75230792\|ref\|ZP_00717255.1\| COG2820: Uridine phosphorylase [Escherichia coli B7A], gi\|191166084\|r... gi\|242379370, gi... - gi\|251787097\|ref\|YP_003001401.1\| hypothetical protein B21_03667 [Escherichia coli BL21], gi\|24237937... gi\|89110189, gi\|... - gi\|89110189\|ref\|AP_003969.1\| uridine phosphorylase [Escherichia coli str. K-12 substr. W3110], gi\|85... EG11045 - uridine phosphorylase / Uridine phosphorylase	200.0	[0..3]	[272..1]
gi\|7473748 - pir\|\|D75306 purine nucleoside phosphorylase - Deinococcus radiodurans (strain R1) gi\|15807160, gi\|... - gi\|6459967\|gb\|AAF11716.1\|AE002050_2 purine nucleoside phosphorylase [Deinococcus radiodurans R1], gi...	200.0	[0..5]	[266..65]
gi\|21957137, gi\|... - gi\|22124359\|ref\|NP_667782.1\| uridine phosphorylase [Yersinia pestis KIM], gi\|21957137\|gb\|AAM84033.1\|... gi\|45437882, gi\|... - gi\|45443015\|ref\|NP_994554.1\| uridine phosphorylase [Yersinia pestis biovar Microtus str. 91001], gi\|...	199.0	[0..2]	[272..15]

Back

Predicted Domain #1

Region A:
Residues: [1-282]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHKKETLPLH LNGDKRDFEG NAGIGRYVIL CGSQERARQI GQSFDQLETK SHPRGHDLYL  60
   61 GTIPHKDHAI EMAAISTGMG CPSTDIILNE LIYLGAKRFL RIGTAGSLQP QWVKTGDVVI 120
  121 ATGAVRDEYT SRCYVDISYP ALASLSMINA AVAAAKALDL ETRTHTGIVH TKDSLYAREF 180
  181 GVSHLKENAE YMQHLKDIGV LASEMESAII FTLAHLHGYR NSKQYREPAK RIKAGSILAI 240
  241 VGDETPVDNN QERINKAIQR ALALGIQTIK FLYESEITAN DF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	52.30103
Match:	1tgvA
Description:	Structure of E. coli Uridine Phosphorylase complexed with 5-Fluorouridine and sulfate
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
purine-nucleoside phosphorylase activity	3.68206997938506	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	3.66765825367784	bayes_pls_golite062009
catalytic activity	2.18268586151113	bayes_pls_golite062009
transferase activity, transferring pentosyl groups	2.01261001022129	bayes_pls_golite062009
S-methyl-5-thioadenosine phosphorylase activity	1.6959166270803	bayes_pls_golite062009
transferase activity	1.42022417161912	bayes_pls_golite062009
nucleobase binding	1.33291775180025	bayes_pls_golite062009
nucleoside binding	1.11256863177576	bayes_pls_golite062009
purine binding	1.00226077276304	bayes_pls_golite062009
binding	0.192121943858605	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: