YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|29654024, gi\|...
Organism:	Coxiella burnetii RSA 493
Length:	235 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|29654024, gi|....

Description	E-value	Query Range	Subject Range
gi\|260685403\|ref... - acetoin:2,6-dichlorophenolindophenol oxidoreductase beta subunit [Clostridium difficile R20291] gi\|126697603, gi... - gi\|126697603\|ref\|YP_001086500.1\| acetoin:2,6-dichlorophenolindophenol oxidoreductase beta subunit [C... gi\|260681806\|ref... - acetoin:2,6-dichlorophenolindophenol oxidoreductase beta subunit [Clostridium difficile CD196] gi\|255099195 - gi\|255099195\|ref\|ZP_05328172.1\| acetoin:2,6-dichlorophenolindophenol oxidoreductase beta subunit [Cl... gi\|255312733 - gi\|255312733\|ref\|ZP_05354316.1\| acetoin:2,6-dichlorophenolindophenol oxidoreductase beta subunit [Cl... gi\|255515494 - gi\|255515494\|ref\|ZP_05383170.1\| acetoin:2,6-dichlorophenolindophenol oxidoreductase beta subunit [Cl... gi\|255648586 - gi\|255648586\|ref\|ZP_05395488.1\| acetoin:2,6-dichlorophenolindophenol oxidoreductase beta subunit [Cl... gi\|145956339, gi... - gi\|90576501\|ref\|ZP_01232962.1\| hypothetical protein CdifQ_02000031 [Clostridium difficile QCD-32g58]... gi\|254973688 - gi\|254973688\|ref\|ZP_05270160.1\| acetoin:2,6-dichlorophenolindophenol oxidoreductase beta subunit [Cl... gi\|255091079 - gi\|255091079\|ref\|ZP_05320557.1\| acetoin:2,6-dichlorophenolindophenol oxidoreductase beta subunit [Cl...	202.0	[0..1]	[208..116]
gi\|167632526, gi... - gi\|167632526\|ref\|ZP_02390853.1\| TPP-dependent acetoin dehydrogenase E1 beta-subunit [Bacillus anthra... gi\|167514423, gi... - gi\|167637874\|ref\|ZP_02396153.1\| TPP-dependent acetoin dehydrogenase E1 beta-subunit [Bacillus anthra... gi\|170670733, gi... - gi\|170685373\|ref\|ZP_02876597.1\| TPP-dependent acetoin dehydrogenase E1 beta-subunit [Bacillus anthra... gi\|170130230, gi... - gi\|170704429\|ref\|ZP_02894895.1\| TPP-dependent acetoin dehydrogenase E1 beta-subunit [Bacillus anthra... gi\|177649687, gi... - gi\|177649687\|ref\|ZP_02932689.1\| TPP-dependent acetoin dehydrogenase E1 beta-subunit [Bacillus anthra... gi\|190563280, gi... - gi\|190565253\|ref\|ZP_03018173.1\| TPP-dependent acetoin dehydrogenase E1 beta-subunit [Bacillus anthra... gi\|30262747, gi\|... - gi\|30262747\|ref\|NP_845124.1\| TPP-dependent acetoin dehydrogenase E1 beta-subunit [Bacillus anthracis... gi\|65320074, gi\|... - gi\|65320074\|ref\|ZP_00393033.1\| COG0022: Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase... gi\|254760630 - gi\|254760630\|ref\|ZP_05212654.1\| TPP-dependent acetoin dehydrogenase E1 beta-subunit [Bacillus anthra... gi\|254752109 - gi\|254752109\|ref\|ZP_05204146.1\| TPP-dependent acetoin dehydrogenase E1 beta-subunit [Bacillus anthra... gi\|254743031 - gi\|254743031\|ref\|ZP_05200716.1\| TPP-dependent acetoin dehydrogenase E1 beta-subunit [Bacillus anthra... gi\|49185594, gi\|... - gi\|49185594\|ref\|YP_028846.1\| TPP-dependent acetoin dehydrogenase E1 beta-subunit [Bacillus anthracis... gi\|254737795 - gi\|254737795\|ref\|ZP_05195498.1\| TPP-dependent acetoin dehydrogenase E1 beta-subunit [Bacillus anthra... gi\|47503215, gi\|... - gi\|47528067\|ref\|YP_019416.1\| TPP-dependent acetoin dehydrogenase E1 beta-subunit [Bacillus anthracis... gi\|165868662, gi... - gi\|165868662\|ref\|ZP_02213322.1\| TPP-dependent acetoin dehydrogenase E1 beta-subunit [Bacillus anthra... gi\|254722747 - gi\|254722747\|ref\|ZP_05184535.1\| TPP-dependent acetoin dehydrogenase E1 beta-subunit [Bacillus anthra... gi\|254685339 - gi\|254685339\|ref\|ZP_05149199.1\| TPP-dependent acetoin dehydrogenase E1 beta-subunit [Bacillus anthra... gi\|229268262, gi... - gi\|229603854\|ref\|YP_002867054.1\| TPP-dependent acetoin dehydrogenase E1 beta-subunit [Bacillus anthr... gi\|227814413, gi... - gi\|227814413\|ref\|YP_002814422.1\| TPP-dependent acetoin dehydrogenase E1 beta-subunit [Bacillus anthr...	201.0	[0..2]	[207..128]
gi\|49479147, gi\|... - gi\|49479147\|ref\|YP_036864.1\| acetoin dehydrogenase (TPP-dependent) E1 component beta subunit [Bacill...	200.0	[0..2]	[207..128]
gi\|52142735, gi\|... - gi\|52142735\|ref\|YP_084093.1\| acetoin dehydrogenase (TPP-dependent) E1 component beta subunit [Bacill... gi\|218903895, gi... - gi\|218903895\|ref\|YP_002451729.1\| TPP-dependent acetoin dehydrogenase E1 beta-subunit [Bacillus cereu... gi\|196027489, gi... - gi\|196041720\|ref\|ZP_03109011.1\| TPP-dependent acetoin dehydrogenase E1 beta-subunit [Bacillus cereus... gi\|195995356, gi... - gi\|196032605\|ref\|ZP_03100019.1\| TPP-dependent acetoin dehydrogenase E1 beta-subunit [Bacillus cereus...	200.0	[0..2]	[207..128]
gi\|42737784, gi\|... - gi\|42781860\|ref\|NP_979107.1\| TPP-dependent acetoin dehydrogenase E1 beta-subunit [Bacillus cereus AT...	200.0	[0..2]	[207..128]
gi\|30020899, gi\|... - gi\|30020899\|ref\|NP_832530.1\| acetoin dehydrogenase E1 component beta-subunit [Bacillus cereus ATCC 1...	200.0	[0..2]	[207..128]
gi\|241769499, gi... - gi\|241769499\|ref\|ZP_04766919.1\| Transketolase central region [Sulfolobus solfataricus 98/2], gi\|2412... gi\|25284433 - pir\|\|F90311 hypothetical protein pdhB-2 [imported] - Sulfolobus solfataricus gi\|15898354, gi\|... - gi\|15898354\|ref\|NP_342959.1\| pyruvate dehydrogenase beta subunit (lipoamide) [Sulfolobus solfataricu...	199.0	[0..3]	[207..116]
gi\|163940523, gi... - gi\|89207402\|ref\|ZP_01185944.1\| Transketolase, central region:Transketolase, C-terminal [Bacillus wei...	199.0	[0..2]	[207..128]
RPA2866 - RPA2866 pyruvate dehydrogenase E1 beta subunit 3242963:3244372 reverse MW:49737	198.0	[0..12]	[208..268]
gi\|47554307, gi\|... - gi\|47569038\|ref\|ZP_00239728.1\| acetoin dehydrogenase, beta subunit [Bacillus cereus G9241], gi\|47554...	198.0	[0..2]	[207..128]

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Predicted Domain #1

Region A:
Residues: [1-235]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVCENLNTTD LAVSSHRAHA HYSAKGDSLK ALIAELYGKV TGVTAGCGGS MNLSDLSIGF  60
   61 VANTAIVAEE SYRYIQQTRK VIEGTDITVV AMSYMTIEAL HAVKFLKAQG IHCELIDLRT 120
  121 IKPLDWETIH ASIRKTGRLL VLDTGFEFCS VASEIIAKTS IDCFSSLLAP PKRLAVPDYP 180
  181 VLTSPTLATP MYTYSDGIVR AVAEVLKSPV NVESLQKERD ARPRDVPGDW FGGPF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	45.39794
Match:	1w85B
Description:	The crystal structure of pyruvate deydrogenase E1 bound to the peripheral subunit binding domain of E2
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.915847726091983	bayes_pls_golite062009
oxidoreductase activity	0.185921344427502	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: