YRC Public Data Repository - Protein Structure Prediction

Protein:	KDSB_COXBU
Organism:	Coxiella burnetii RSA 493
Length:	249 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for KDSB_COXBU.

Description	E-value	Query Range	Subject Range
KDSB_COXBR - 3-deoxy-manno-octulosonate cytidylyltransferase OS=Coxiella burnetii (strain RSA 331 / Henzerling II...	193.0	[0..1]	[249..1]
gi\|197361929, gi... - gi\|197361929\|ref\|YP_002141566.1\| TDP-glucose pyrophosphorylase [Salmonella enterica subsp. enterica ... gi\|56127258, gi\|... - gi\|56413001\|ref\|YP_150076.1\| TDP-glucose pyrophosphorylase [Salmonella enterica subsp. enterica sero...	189.0	[0..1]	[248..1]
gi\|25288650, gi\|... - gi\|25288650\|pir\|\|AD0767 glucose-1-phosphate thymidylyltransferase (EC 2.7.7.24) - Salmonella enteric... gi\|213650449 - gi\|213650449\|ref\|ZP_03380502.1\| TDP-glucose pyrophosphorylase [Salmonella enterica subsp. enterica s... gi\|29136903, gi\|... - gi\|29141277\|ref\|NP_804619.1\| TDP-glucose pyrophosphorylase [Salmonella enterica subsp. enterica sero... gi\|213425547 - gi\|213425547\|ref\|ZP_03358297.1\| TDP-glucose pyrophosphorylase [Salmonella enterica subsp. enterica s... gi\|214001793 - gi\|214001793\|ref\|ZP_03412528.1\| TDP-glucose pyrophosphorylase [Salmonella enterica subsp. enterica s... gi\|16761027 - gi\|16761027\|ref\|NP_456644.1\| TDP-glucose pyrophosphorylase [Salmonella enterica subsp. enterica sero... gi\|213052827 - gi\|213052827\|ref\|ZP_03345705.1\| TDP-glucose pyrophosphorylase [Salmonella enterica subsp. enterica s...	189.0	[0..1]	[248..1]
gi\|1098479 - gi\|1098479\|gb\|AAC37050.1\| glucose-1-phosphate thymidyl transferase [Neisseria meningitidis]	188.0	[0..2]	[248..13]
gi\|34811708, gi\|... - gi\|34811708\|pdb\|1H5S\|B Chain B, Thymidylyltransferase Complexed With Tmp, gi\|21466153\|pdb\|1H5T\|B Cha...	188.0	[0..1]	[248..1]
gi\|34105319, gi\|... - gi\|34499467\|ref\|NP_903682.1\| glucose-1-phosphate thymidylyltransferase [Chromobacterium violaceum AT...	188.0	[0..1]	[248..8]
gi\|9957822 - gi\|9957822\|gb\|AAG09504.1\|AF279616_3 glucose-1-phosphate thymidylyltransferase [Salmonella enterica]	188.0	[0..1]	[248..1]
RMLA1_SHIFL - Glucose-1-phosphate thymidylyltransferase 1 OS=Shigella flexneri GN=rfbA PE=3 SV=2 gi\|24113424, gi\|... - gi\|24113424\|ref\|NP_707934.1\| glucose-1-phosphate thymidylyltransferase [Shigella flexneri 2a str. 30... gi\|30063490, gi\|... - gi\|30063490\|ref\|NP_837661.1\| glucose-1-phosphate thymidylyltransferase [Shigella flexneri 2a str. 24...	187.0	[0..1]	[248..1]
gi\|72132990 - gi\|72132990\|gb\|AAZ66343.1\| RmlA [Listonella anguillarum]	187.0	[0..1]	[248..1]

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Predicted Domain #1

Region A:
Residues: [1-249]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEFRVIIPAR FDSTRLPGKA LVDIAGKPMI QHVYESAIKS GAEEVVIATD DKRIRQVAED  60
   61 FGAVVCMTSS DHQSGTERIA EAAVALGFED DEIIVCLQGD EPLIPPDAIR KLAEDLDEHD 120
  121 NVKVASLCTP ITEVDELFNP HSTKVVLNRR NYALYFSHAP IPWGRDTFSD KENLQLNGSH 180
  181 YRHVGIYAYR VGFLEEYLSW DACPAEKMEA LEQLRILWHG GRIHMVVAKS KCPPGVDTEE 240
  241 DLERVRAYF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	46.0
Match:	1vh1A
Description:	Crystal structure of CMP-KDO synthetase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
polypeptide N-acetylgalactosaminyltransferase activity	2.87534754775824	bayes_pls_golite062009
3-deoxy-manno-octulosonate cytidylyltransferase activity	2.75368830096228	bayes_pls_golite062009
catalytic activity	2.25720704697246	bayes_pls_golite062009
transferase activity, transferring hexosyl groups	2.04393180556087	bayes_pls_golite062009
transferase activity	1.67251862595728	bayes_pls_golite062009
UDP-glycosyltransferase activity	1.51711005399931	bayes_pls_golite062009
cytidylyltransferase activity	1.30540294475078	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	1.21894113759929	bayes_pls_golite062009
UDP-N-acetylglucosamine diphosphorylase activity	0.696745721981411	bayes_pls_golite062009
nucleotidyltransferase activity	0.67147527259372	bayes_pls_golite062009
uridylyltransferase activity	0.54930147038803	bayes_pls_golite062009
acetylgalactosaminyltransferase activity	0.48277064848483	bayes_pls_golite062009
mannose-phosphate guanylyltransferase activity	0.38929738612511	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.280335197569099	bayes_pls_golite062009
galactosyltransferase activity	0.21201767008409	bayes_pls_golite062009
glucose-1-phosphate thymidylyltransferase activity	0.204810937394121	bayes_pls_golite062009
guanylyltransferase activity	0.14847697203788	bayes_pls_golite062009
2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase activity	0.00302319544700058	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: