YRC Public Data Repository - Protein Structure Prediction

Protein:	PYRE_COXBU
Organism:	Coxiella burnetii RSA 493
Length:	209 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PYRE_COXBU.

Description	E-value	Query Range	Subject Range
gi\|254852737 - gi\|254852737\|ref\|ZP_05242085.1\| orotate phosphoribosyltransferase [Listeria monocytogenes FSL R2-503... gi\|254826127 - gi\|254826127\|ref\|ZP_05231128.1\| orotate phosphoribosyltransferase [Listeria monocytogenes FSL J1-194... gi\|254878051 - gi\|254878051\|ref\|ZP_05250761.1\| orotate phosphoribosyltransferase [Listeria monocytogenes FSL J2-071... PYRE_LISMF - Orotate phosphoribosyltransferase OS=Listeria monocytogenes serotype 4b (strain F2365) GN=pyrE PE=3 ... gi\|47093068, gi\|... - gi\|47093068\|ref\|ZP_00230846.1\| orotate phosphoribosyltransferase [Listeria monocytogenes str. 4b H78... gi\|254933303, gi... - gi\|254933303\|ref\|ZP_05266662.1\| orotate phosphoribosyltransferase [Listeria monocytogenes HPB2262], ... gi\|226224434, gi... - gi\|226224434\|ref\|YP_002758541.1\| orotate phosphoribosyltransferase [Listeria monocytogenes Clip81459...	196.0	[0..1]	[208..1]
PYRE_LISIN - Orotate phosphoribosyltransferase OS=Listeria innocua serovar 6a (strain CLIP 11262) GN=pyrE PE=3 SV... PYRE_LISIN - Orotate phosphoribosyltransferase OS=Listeria innocua GN=pyrE PE=3 SV=1	195.0	[0..1]	[208..1]
gi\|224501368 - gi\|224501368\|ref\|ZP_03669675.1\| orotate phosphoribosyltransferase [Listeria monocytogenes FSL R2-561... PYRE_LISMO - Orotate phosphoribosyltransferase OS=Listeria monocytogenes serovar 1/2a (strain ATCC BAA-679 / EGD-... PYRE_LISMO - Orotate phosphoribosyltransferase OS=Listeria monocytogenes GN=pyrE PE=3 SV=1	195.0	[0..1]	[208..1]
gi\|255025732 - gi\|255025732\|ref\|ZP_05297718.1\| orotate phosphoribosyltransferase [Listeria monocytogenes FSL J2-003... gi\|254831568, gi... - gi\|254831568\|ref\|ZP_05236223.1\| orotate phosphoribosyltransferase [Listeria monocytogenes 10403S], g... gi\|224500062 - gi\|224500062\|ref\|ZP_03668411.1\| orotate phosphoribosyltransferase [Listeria monocytogenes Finland 19... gi\|47096552, gi\|... - gi\|47096552\|ref\|ZP_00234142.1\| orotate phosphoribosyltransferase [Listeria monocytogenes str. 1/2a F... gi\|153183321, gi... - gi\|254899472\|ref\|ZP_05259396.1\| orotate phosphoribosyltransferase [Listeria monocytogenes J0161], gi... gi\|254936716, gi... - gi\|254936716\|ref\|ZP_05268413.1\| orotate phosphoribosyltransferase [Listeria monocytogenes F6900], gi... gi\|153191338, gi... - gi\|254912389\|ref\|ZP_05262401.1\| orotate phosphoribosyltransferase [Listeria monocytogenes J2818], gi...	195.0	[0..1]	[208..1]
gi\|56379534, gi\|... - gi\|56419692\|ref\|YP_147010.1\| orotate phosphoribosyltransferase [Geobacillus kaustophilus HTA426], gi...	179.0	[0..3]	[208..1]
gi\|90821002, gi\|... - gi\|90961808\|ref\|YP_535724.1\| orotate phosphoribosyltransferase [Lactobacillus salivarius UCC118], gi...	178.0	[0..5]	[207..2]
gi\|227070533, gi... - gi\|227364440\|ref\|ZP_03848530.1\| orotate phosphoribosyltransferase [Lactobacillus reuteri MM2-3], gi\|... gi\|227531675, gi... - gi\|227531675\|ref\|ZP_03961724.1\| orotate phosphoribosyltransferase [Lactobacillus reuteri MM4-1A], gi... gi\|183224120, gi... - gi\|89091269\|ref\|ZP_01164285.1\| Orotate phosphoribosyl transferase [Lactobacillus reuteri JCM 1112], ...	177.0	[0..1]	[207..1]
PYRE_BACCL - Orotate phosphoribosyltransferase OS=Bacillus caldolyticus GN=pyrE PE=2 SV=1	175.0	[0..3]	[208..1]
gi\|23025119, gi\|... - gi\|23025119\|ref\|ZP_00064292.1\| COG0461: Orotate phosphoribosyltransferase [Leuconostoc mesenteroides...	175.0	[0..2]	[208..3]
gi\|48824551 - ref\|ZP_00285910.1\| COG0461: Orotate phosphoribosyltransferase [Enterococcus faecium] gi\|69247608, gi\|... - gi\|69247608\|ref\|ZP_00604419.1\| Orotate phosphoribosyl transferase [Enterococcus faecium DO], gi\|6819...	174.0	[0..1]	[208..1]

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Predicted Domain #1

Region A:
Residues: [1-209]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNQATEIAKL LLNIKAVTLN LHEPYRYTSG ILSPIYCDNR LIISYPEKRK MIIEAFLQLI  60
   61 EKNHLSFDIV AGTATAGIPH AAWIADRLDL PMIYVRAKAK THGKQNQIEG RIRKGQRALI 120
  121 VEDLISTGKS ALAAGLALRE KGVTVTDCIA IFSYQLPQAQ QNFSDANINC HALSHFDTLI 180
  181 EMAVDEGYID EIEKQKALAW NKDPEHWQP

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	39.69897
Match:	2aeeA
Description:	Crystal structure of Orotate phosphoribosyltransferase from Streptococcus pyogenes
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
transferase activity, transferring pentosyl groups	3.03016109611914	bayes_pls_golite062009
catalytic activity	2.67475805095976	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	2.53464204724265	bayes_pls_golite062009
transferase activity	2.23444207913717	bayes_pls_golite062009
orotate phosphoribosyltransferase activity	1.74456227958952	bayes_pls_golite062009
ribose phosphate diphosphokinase activity	1.7212298503296	bayes_pls_golite062009
amidophosphoribosyltransferase activity	1.14461122399598	bayes_pls_golite062009
diphosphotransferase activity	0.98427504031068	bayes_pls_golite062009
hypoxanthine phosphoribosyltransferase activity	0.824877195846631	bayes_pls_golite062009
uracil phosphoribosyltransferase activity	0.52776253385781	bayes_pls_golite062009
adenine phosphoribosyltransferase activity	0.46065288387965	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: