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View Structure Prediction Details

Protein: gi|29653447, gi|...
Organism: Coxiella burnetii RSA 493
Length: 252 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|29653447, gi|....

Description E-value Query
Range
Subject
Range
gi|154707351, gi... - gi|94492500|ref|ZP_01299707.1| hypothetical protein CburD_01000077 [Coxiella burnetii Dugway 7E9-12]...
200.0 [0..1] [252..1]
gi|95927728, gi|... - gi|95927728|ref|ZP_01310482.1| hypothetical protein CburR_01000492 [Coxiella burnetii RSA 331], gi|1...
196.0 [0..1] [252..1]
gi|28854162, gi|... - gi|28870913|ref|NP_793532.1| hypothetical protein PSPTO_3758 [Pseudomonas syringae pv. tomato str. D...
tr|Q87YN7|Q87YN7... - Uncharacterized protein OS=Pseudomonas syringae pv. tomato (strain DC3000) GN=PSPTO_3758 PE=4 SV=1
184.0 [0..6] [250..4]
gi|71556614, gi|... - gi|71736061|ref|YP_275710.1| hypothetical protein PSPPH_3562 [Pseudomonas syringae pv. phaseolicola ...
183.0 [0..6] [250..4]
gi|88934168, gi|... - gi|88934168|ref|ZP_01139812.1| conserved hypothetical protein [Geobacter uraniumreducens Rf4], gi|88...
182.0 [0..7] [249..13]
PDCH_COMTE - 2-pyrone-4,6-dicarbaxylate hydrolase OS=Comamonas testosteroni PE=3 SV=1
181.0 [0..3] [248..25]
gi|66044967, gi|... - gi|66044967|ref|YP_234808.1| amidohydrolase 2 [Pseudomonas syringae pv. syringae B728a], gi|63255674...
180.0 [0..6] [250..4]
RPA1080 - RPA1080 possible 2-pyrone-4,6-dicarboxylate hydrolase 1188686:1189588 forward MW:32571
179.0 [0..3] [250..30]
gi|90415600|ref|... - 2-pyrone-4,6-dicarboxylic acid hydrolase [marine gamma proteobacterium HTCC2207]
gi|90415600, gi|... - gi|90415600|ref|ZP_01223534.1| 2-pyrone-4,6-dicarboxylic acid hydrolase [marine gamma proteobacteriu...
178.0 [0..3] [248..28]
gi|39573668 - gi|39573668|dbj|BAD04056.1| 2-pyrone-4,6-dicarboxylate lactonase [Pseudomonas straminea]
177.0 [0..3] [248..25]

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Predicted Domain #1
Region A:
Residues: [1-252]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MQTRLIFDSH FHIIDPRFPL IPNQGFVPSS FTVDDYLSVT KGLNIVGGAI VSGSFQGFDQ  60
   61 TYLESALQKL GNHFVGATQL PGTASEEEIK ELHKKGVRAV RFNLKRGGSA SVGDCESLAK 120
  121 RVFNVAGWHS EFYVDSRDLP AISPLLEKLP AIVIDHLGLS KAGFPFLLKL IEKGAYVKAS 180
  181 GFGRLDFSII AALQQIIAIN PASLLFGTDL PSTRAPRPFM IEDIRLIEEN FSSEIAGKIF 240
  241 YNNALKPYDV RL

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 40.522879
Match: 2ffiA
Description: Crystal Structure of Putative 2-Pyrone-4,6-Dicarboxylic Acid Hydrolase from Pseudomonas putida, Northeast Structural Genomics Target PpR23.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 1.70199291046899 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 1.22643765612148 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines 0.573107361273483 bayes_pls_golite062009
hydrolase activity 0.0601688046184598 bayes_pls_golite062009
deaminase activity 0.0589623696103007 bayes_pls_golite062009

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