YRC Public Data Repository - Protein Structure Prediction

Protein:	NADC_SYNY3
Organism:	Synechocystis sp. PCC 6803 substr. Kazusa
Length:	295 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for NADC_SYNY3.

Description	E-value	Query Range	Subject Range
gi\|37199711, gi\|... - gi\|37680961\|ref\|NP_935570.1\| quinolinate phosphoribosyltransferase [Vibrio vulnificus YJ016], gi\|371...	322.0	[0..9]	[292..23]
gi\|91228624, gi\|... - gi\|91228624\|ref\|ZP_01262541.1\| nicotinate-nucleotide pyrophosphorylase [Vibrio alginolyticus 12G01],...	322.0	[0..9]	[292..11]
gi\|16930777 - gi\|16930777\|gb\|AAL32048.1\|AF439854_1 NadC [Vibrio vulnificus]	321.0	[0..9]	[292..11]
gi\|110803622, gi... - gi\|110803622\|ref\|YP_697707.1\| nicotinate-nucleotide pyrophosphorylase [Clostridium perfringens SM101...	321.0	[0..18]	[294..3]
gi\|77995232, gi\|... - gi\|78043117\|ref\|YP_361169.1\| nicotinate-nucleotide pyrophosphorylase [Carboxydothermus hydrogenoform...	320.0	[0..15]	[292..1]
gi\|110168804, gi... - gi\|71676261\|ref\|ZP_00674003.1\| Nicotinate-nucleotide pyrophosphorylase [Trichodesmium erythraeum IMS...	320.0	[0..16]	[294..6]
gi\|48857399, gi\|... - gi\|67917198\|ref\|ZP_00510863.1\| Nicotinate-nucleotide pyrophosphorylase [Clostridium thermocellum ATC...	320.0	[0..20]	[292..6]
gi\|77381015, gi\|... - gi\|77457012\|ref\|YP_346517.1\| nicotinate-nucleotide pyrophosphorylase [Pseudomonas fluorescens Pf0-1]...	319.0	[0..6]	[292..1]
gi\|27361137, gi\|... - gi\|27364991\|ref\|NP_760519.1\| quinolinate phosphoribosyltransferase [Vibrio vulnificus CMCP6], gi\|273...	319.0	[0..9]	[292..11]
gi\|126198042, gi... - gi\|84322942\|ref\|ZP_00971019.1\| COG0157: Nicotinate-nucleotide pyrophosphorylase [Pseudomonas aerugin...	318.0	[0..6]	[292..1]

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Predicted Domain #1

Region A:
Residues: [1-295]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMRILVTNPA PMTCLPPWII IDPWLQQWLA EDIGRGDWST QGLGLQHRGQ ARWVAKENGV  60
   61 IAGLPMAARI FQLLDPSMEF QVLAGEGQAV TASTVVATMA GNLGSLLTGE RVALNLVMGL 120
  121 SGIATMTRQY VQAIADYPTR FVDTRKTTPG LRVLEKYASR LGGAMNHRLG LDDAVMVKDN 180
  181 HIQAAGSITK AVQTLRQNLP YPLAIEVETS NLEEVQEAIA TQVEIIMLDN MGTDTMATAV 240
  241 KLIRQANPLI RIEASGNVTL ANLTAIASTG VDFISSSAPI TRSPWLDLSM QIVRN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	83.522879
Match:	1qapA
Description:	Quinolinic acid phosphoribosyltransferase (Nicotinate-nucleotide pyrophosphorylase, NadC), C-terminal domain; Quinolinic acid phosphoribosyltransferase (Nicotinate-nucleotide pyrophosphorylase, NadC), N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
nicotinate phosphoribosyltransferase activity	3.4096751090496	bayes_pls_golite062009
nicotinate-nucleotide diphosphorylase (carboxylating) activity	3.12788282156037	bayes_pls_golite062009
binding	1.58263447797054	bayes_pls_golite062009
catalytic activity	0.60409960326459	bayes_pls_golite062009
protein binding	0.502035039039958	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: