YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|1773099
Organism:	Escherichia coli
Length:	188 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|1773099.

Description	E-value	Query Range	Subject Range
gi\|91209483, gi\|... - gi\|91209483\|ref\|YP_539469.1\| riboflavin synthase beta chain [Escherichia coli UTI89], gi\|91071057\|gb... gi\|117622676, gi... - gi\|117622676\|ref\|YP_851589.1\| riboflavin synthase subunit beta [Escherichia coli APEC O1], gi\|115511... gi\|226898801, gi... - gi\|237707591\|ref\|ZP_04538072.1\| riboflavin synthase subunit beta [Escherichia sp. 3_2_53FAA], gi\|226...	265.0	[0..1]	[188..1]
gi\|11280455 - gi\|11280455\|pir\|\|C82098 riboflavin synthase, beta chain VC2268 [similarity] - Vibrio cholerae (strai... gi\|227082392, gi... - gi\|227082392\|ref\|YP_002810943.1\| 6,7-dimethyl-8-ribityllumazine synthase [Vibrio cholerae M66-2], gi... gi\|229512146, gi... - gi\|229512146\|ref\|ZP_04401625.1\| 6,7-dimethyl-8-ribityllumazine synthase [Vibrio cholerae B33], gi\|22... gi\|229507659, gi... - gi\|229507659\|ref\|ZP_04397164.1\| 6,7-dimethyl-8-ribityllumazine synthase [Vibrio cholerae BX 330286],... gi\|148876330, gi... - gi\|153828241\|ref\|ZP_01980908.1\| 6,7-dimethyl-8-ribityllumazine synthase [Vibrio cholerae 623-39], gi... gi\|229519281, gi... - gi\|229519281\|ref\|ZP_04408724.1\| 6,7-dimethyl-8-ribityllumazine synthase [Vibrio cholerae RC9], gi\|22... gi\|227014164, gi... - gi\|227118714\|ref\|YP_002820610.1\| 6,7-dimethyl-8-ribityllumazine synthase [Vibrio cholerae O395], gi\|... gi\|229513909, gi... - gi\|229513909\|ref\|ZP_04403371.1\| 6,7-dimethyl-8-ribityllumazine synthase [Vibrio cholerae TMA 21], gi... gi\|229337851, gi... - gi\|229524270\|ref\|ZP_04413675.1\| 6,7-dimethyl-8-ribityllumazine synthase [Vibrio cholerae bv. albensi... gi\|9656830, gi\|1... - gi\|9656830\|gb\|AAF95412.1\| riboflavin synthase, beta subunit [Vibrio cholerae O1 biovar El Tor str. N... gi\|229522213, gi... - gi\|229522213\|ref\|ZP_04411630.1\| 6,7-dimethyl-8-ribityllumazine synthase [Vibrio cholerae TM 11079-80... gi\|229369818, gi... - gi\|229607163\|ref\|YP_002877811.1\| 6,7-dimethyl-8-ribityllumazine synthase [Vibrio cholerae MJ-1236], ... gi\|229332505, gi... - gi\|229528731\|ref\|ZP_04418121.1\| 6,7-dimethyl-8-ribityllumazine synthase [Vibrio cholerae 12129(1)], ... gi\|254849397, gi... - gi\|254849397\|ref\|ZP_05238747.1\| 6,7-dimethyl-8-ribityllumazine synthase [Vibrio cholerae MO10], gi\|2... gi\|121628513, gi... - gi\|121729762\|ref\|ZP_01682201.1\| 6,7-dimethyl-8-ribityllumazine synthase [Vibrio cholerae V52], gi\|12... gi\|121549601, gi... - gi\|121586189\|ref\|ZP_01675980.1\| 6,7-dimethyl-8-ribityllumazine synthase [Vibrio cholerae 2740-80], g... gi\|153803020, gi... - gi\|153803020\|ref\|ZP_01957606.1\| 6,7-dimethyl-8-ribityllumazine synthase [Vibrio cholerae MZO-3], gi\|... gi\|124119721, gi... - gi\|153221374\|ref\|ZP_01952352.1\| 6,7-dimethyl-8-ribityllumazine synthase [Vibrio cholerae MAK 757], g... gi\|150423971, gi... - gi\|254286061\|ref\|ZP_04961022.1\| 6,7-dimethyl-8-ribityllumazine synthase [Vibrio cholerae AM-19226], ... gi\|126509070, gi... - gi\|153820385\|ref\|ZP_01973052.1\| 6,7-dimethyl-8-ribityllumazine synthase [Vibrio cholerae NCTC 8457],...	253.0	[0..16]	[188..1]
gi\|67085733, gi\|... - gi\|67157056\|ref\|ZP_00418418.1\| 6,7-dimethyl-8-ribityllumazine synthase [Azotobacter vinelandii AvOP]...	248.0	[0..4]	[188..3]
gi\|37679048, gi\|... - gi\|37679048\|ref\|NP_933657.1\| riboflavin synthase subunit beta [Vibrio vulnificus YJ016], gi\|37197790...	244.0	[0..16]	[188..1]
gi\|110804437, gi... - gi\|110804437\|ref\|YP_687957.1\| riboflavin synthase subunit beta [Shigella flexneri 5 str. 8401], gi\|1...	239.0	[0..16]	[188..2]
RISB_VIBPA - 6,7-dimethyl-8-ribityllumazine synthase OS=Vibrio parahaemolyticus GN=ribH PE=3 SV=1 gi\|219549220, gi... - gi\|254507847\|ref\|ZP_05119977.1\| 6,7-dimethyl-8-ribityllumazine synthase [Vibrio parahaemolyticus 16]... RISB_VIBCB - 6,7-dimethyl-8-ribityllumazine synthase OS=Vibrio campbellii (strain ATCC BAA-1116 / BB120) GN=ribH ... RISB_VIBPA - 6,7-dimethyl-8-ribityllumazine synthase OS=Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 22106...	236.0	[0..33]	[188..1]
gi\|75814844 - gi\|75814844\|ref\|ZP_00745389.1\| COG0054: Riboflavin synthase beta-chain [Vibrio cholerae V52] gi\|75827556 - gi\|75827556\|ref\|ZP_00756991.1\| COG0054: Riboflavin synthase beta-chain [Vibrio cholerae O395] RISB_VIBCH - 6,7-dimethyl-8-ribityllumazine synthase OS=Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor I... RISB_VIBCH - 6,7-dimethyl-8-ribityllumazine synthase OS=Vibrio cholerae GN=ribH PE=3 SV=2 gi\|75828877, gi\|... - gi\|75828877\|ref\|ZP_00758209.1\| COG0054: Riboflavin synthase beta-chain [Vibrio cholerae MO10], gi\|11...	234.0	[0..33]	[188..1]
gi\|126699303, gi... - gi\|126699303\|ref\|YP_001088200.1\| riboflavin synthase beta chain (6,7-dimethyl-8-ribityllumazine synt... gi\|255100828 - gi\|255100828\|ref\|ZP_05329805.1\| riboflavin synthase beta chain (6,7-dimethyl-8-ribityllumazine synth... gi\|255306717 - gi\|255306717\|ref\|ZP_05350888.1\| riboflavin synthase beta chain (6,7-dimethyl-8-ribityllumazine synth...	234.0	[0..35]	[186..2]
gi\|255314462 - gi\|255314462\|ref\|ZP_05356045.1\| riboflavin synthase beta chain (6,7-dimethyl-8-ribityllumazine synth... gi\|255517139 - gi\|255517139\|ref\|ZP_05384815.1\| riboflavin synthase beta chain (6,7-dimethyl-8-ribityllumazine synth... gi\|255650244 - gi\|255650244\|ref\|ZP_05397146.1\| riboflavin synthase beta chain (6,7-dimethyl-8-ribityllumazine synth... gi\|254975333 - gi\|254975333\|ref\|ZP_05271805.1\| riboflavin synthase beta chain (6,7-dimethyl-8-ribityllumazine synth... gi\|255092724 - gi\|255092724\|ref\|ZP_05322202.1\| riboflavin synthase beta chain (6,7-dimethyl-8-ribityllumazine synth... gi\|145954563, gi... - gi\|90574741\|ref\|ZP_01231233.1\| hypothetical protein CdifQ_02001808 [Clostridium difficile QCD-32g58]...	234.0	[0..35]	[186..2]
gi\|84394360, gi\|... - gi\|84394360\|ref\|ZP_00993081.1\| riboflavin synthase subunit beta [Vibrio splendidus 12B01], gi\|843750... gi\|85834727, gi\|... - gi\|86147434\|ref\|ZP_01065746.1\| riboflavin synthase subunit beta [Vibrio sp. MED222], gi\|85834727\|gb\|...	233.0	[0..33]	[188..1]

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Predicted Domain #1

Region A:
Residues: [1-188]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MHDLPARKGS SARNIMLKSA PLRGHTRTRR KKMNIIEANV ATPDARVAIT IARFNNFIND  60
   61 SLLEGAIDAL KRIGQVKDEN ITVVWVPGAY ELPLAAGALA KTGKYDAVIA LGTVIRGGTA 120
  121 HFEYVAGGAS NGLAHVAQDS EIPVAFGVLT TESIEQAIER AGTKAGNKGA EAALTALEMI 180
  181 NVLKAIKA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	58.09691
Match:	1rvvA
Description:	Lumazine synthase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
6,7-dimethyl-8-ribityllumazine synthase activity	5.61825642183907	bayes_pls_golite062009
intramolecular transferase activity, transferring acyl groups	4.02275160603209	bayes_pls_golite062009
catalytic activity	1.78070169551865	bayes_pls_golite062009
riboflavin synthase activity	1.72639804812167	bayes_pls_golite062009
isomerase activity	0.233413658370014	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: