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View Structure Prediction Details

Protein: MURC_SHEON
Organism: Shewanella oneidensis MR-1
Length: 488 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MURC_SHEON.

Description E-value Query
Range
Subject
Range
gi|116183852, gi... - gi|75854403|ref|ZP_00762098.1| COG0773: UDP-N-acetylmuramate-alanine ligase [Vibrio sp. Ex25], gi|11...
401.0 [0..1] [480..3]
gi|91228515, gi|... - gi|91228515|ref|ZP_01262437.1| UDP-N-acetylmuramate--L-alanine ligase [Vibrio alginolyticus 12G01], ...
399.0 [0..1] [474..3]
MURC_VIBPA - UDP-N-acetylmuramate--L-alanine ligase OS=Vibrio parahaemolyticus serotype O3:K6 (strain RIMD 221063...
gi|153839043, gi... - gi|153839043|ref|ZP_01991710.1| UDP-N-acetylmuramate--alanine ligase [Vibrio parahaemolyticus AQ3810...
MURC_VIBPA - UDP-N-acetylmuramate--L-alanine ligase OS=Vibrio parahaemolyticus GN=murC PE=3 SV=1
399.0 [0..1] [480..3]
gi|28897235, gi|... - gi|28897235|ref|NP_796840.1| UDP-N-acetylmuramate--L-alanine ligase [Vibrio parahaemolyticus RIMD 22...
gi|28805444 - gi|28805444|dbj|BAC58724.1| UDP-N-acetylmuramate-alanine ligase [Vibrio parahaemolyticus RIMD 221063...
399.0 [0..1] [480..8]
MURC_SHESM - UDP-N-acetylmuramate--L-alanine ligase OS=Shewanella sp. (strain MR-4) GN=murC PE=3 SV=1
397.0 [0..1] [488..1]
MURC_SHESR - UDP-N-acetylmuramate--L-alanine ligase OS=Shewanella sp. (strain MR-7) GN=murC PE=3 SV=1
397.0 [0..1] [488..1]
MURC_SHESA - UDP-N-acetylmuramate--L-alanine ligase OS=Shewanella sp. (strain ANA-3) GN=murC PE=3 SV=1
395.0 [0..1] [488..1]
MURC_PHOPR - UDP-N-acetylmuramate--L-alanine ligase OS=Photobacterium profundum GN=murC PE=3 SV=1
MURC_PHOPR - UDP-N-acetylmuramate--L-alanine ligase OS=Photobacterium profundum (strain SS9) GN=murC PE=3 SV=1
388.0 [0..5] [475..8]
gi|90326056, gi|... - gi|90413041|ref|ZP_01221039.1| UDP-N-acetylmuramate--L-alanine ligase [Photobacterium profundum 3TCK...
387.0 [0..1] [475..1]
gi|86148541, gi|... - gi|86148541|ref|ZP_01066828.1| UDP-N-acetylmuramate--L-alanine ligase [Vibrio sp. MED222], gi|858336...
385.0 [0..1] [475..3]

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Predicted Domain #1
Region A:
Residues: [1-488]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTKTERYLQL RSMIPEMRRI KRIHFVGIGG AGMGGIAEVL VNEGYVVSGS DIAQNAVTDR  60
   61 LCLLGAKIHI GHGADNVQQA DVVVVSTAIN PQNPEIIAAK ELRIPIVRRA EMLAELMRYR 120
  121 HGVAIAGTHG KTTTTSLIAS LYGQAGRDPT FVIGGLLNSA GTNARLGTSR YLIAEADESD 180
  181 ASFLHLQPMV SVVTNIEADH MDTYGGDFEK LKSTFVDFLH NLPFYGVAVV CIDDPVVREI 240
  241 MPRISRHIVT YGFRDDADVQ ALNFSQQGHQ CRFTVRRKGK EDLDLLLNLP GQHNVLNALA 300
  301 AIAVATEDEI DDSAIIQALA EFQGIGRRFQ HLGKFATPKG EVMLVDDYGH HPSEVAATIK 360
  361 AARAGWPEKR LVMAYQPHRY TRTRDLYEDF IEVLSQVDCL LLLDVYSAGE APIPGADGRA 420
  421 LCRSIRLRGQ LDPIFIASPE QLAEVLPDVL QEGDLLLTQG AGNIGALSRK LAASELGFST 480
  481 GATTEVKP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 101.0
Match: 1gqqA
Description: UDP-N-acetylmuramate-alanine ligase MurC
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
acid-amino acid ligase activity 4.69457467817524 bayes_pls_golite062009
catalytic activity 2.32193352101012 bayes_pls_golite062009
ligase activity 2.23577665688762 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 1.49014759290314 bayes_pls_golite062009
binding 0.57191595271726 bayes_pls_golite062009
protein binding 0.153129049437399 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle