YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|24375411, gi\|...
Organism:	Shewanella oneidensis MR-1
Length:	479 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|24375411, gi|....

Description	E-value	Query Range	Subject Range
gi\|78688300, gi\|... - gi\|78688300\|ref\|ZP_00853007.1\| thiH protein, putative [Shewanella sp. ANA-3], gi\|78503964\|gb\|EAP1755...	352.0	[0..1]	[479..1]
gi\|113886269, gi... - gi\|82498460\|ref\|ZP_00883956.1\| thiH protein, putative [Shewanella sp. MR-4], gi\|82403546\|gb\|EAP44271...	352.0	[0..1]	[479..1]
gi\|78357321, gi\|... - gi\|78357321\|ref\|YP_388770.1\| thiamine biosynthesis protein ThiH [Desulfovibrio desulfuricans subsp. ...	346.0	[0..20]	[479..11]
gi\|4981824, gi\|1... - gi\|4981824\|gb\|AAD36342.1\|AE001782_3 thiH protein, putative [Thermotoga maritima MSB8], gi\|15644023\|r... gi\|7462818 - pir\|\|B72274 hypothetical protein TM1267 - Thermotoga maritima (strain MSB8)	322.0	[0..20]	[477..16]
gi\|18143767, gi\|... - gi\|18309092\|ref\|NP_561026.1\| thiamine biosynthesis protein ThiH [Clostridium perfringens str. 13], g...	309.0	[0..15]	[477..8]
gi\|110684229, gi... - gi\|110803728\|ref\|YP_697445.1\| thiamine biosynthesis protein ThiH [Clostridium perfringens SM101], gi...	308.0	[0..15]	[477..8]
gi\|110799003, gi... - gi\|110799003\|ref\|YP_694570.1\| thiamine biosynthesis protein ThiH [Clostridium perfringens ATCC 13124...	307.0	[0..15]	[477..8]
gi\|89210452, gi\|... - gi\|89210452\|ref\|ZP_01188841.1\| Radical SAM:Biotin and thiamin synthesis associated [Halothermothrix ...	306.0	[0..20]	[478..21]
gi\|196198564, gi... - gi\|196251975\|ref\|ZP_03150639.1\| biotin and thiamin synthesis associated [Clostridium thermocellum DS... gi\|67849547, gi\|... - gi\|67916513\|ref\|ZP_00510221.1\| Radical SAM:Biotin and thiamin synthesis associated [Clostridium ther...	305.0	[0..18]	[478..5]
gi\|28211009, gi\|... - gi\|28211009\|ref\|NP_781953.1\| thiamine biosynthesis protein ThiH [Clostridium tetani E88], gi\|2820344...	302.0	[0..20]	[477..16]

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Predicted Domain #1

Region A:
Residues: [1-65]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSTHEHHSIT LSDYNPNVNF IDDKAIWQTI EDASDPSREQ VLAILDKARQ CEGLSISETA  60
   61 LLLQN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	13.30103
Match:	2a5hA
Description:	2.1 Angstrom X-ray crystal structure of lysine-2,3-aminomutase from Clostridium subterminale SB4, with Michaelis analog (L-alpha-lysine external aldimine form of pyridoxal-5'-phosphate).
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [66-479]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QDKTLDEMLF SVAREIKNTI YGNRIVMFAP LYVSNHCANS CSYCGFNADN HELKRKTLKQ  60
   61 DEIRQEVAIL EEMGHKRILA VYGEHPRNNV QAIVESIQTM YSVKQGKGGE IRRINVNCAP 120
  121 MSVEDFKQLK TAAIGTYQCF QETYHQDTYS QVHLKGKKTD FLYRLYAMHR AMEAGIDDVG 180
  181 IGALFGLYDH RFELLAMLTH VQQLEKDCGV GPHTISFPRI EPAHGSAISE KPPYEVDDDC 240
  241 FKRIVAITRL AVPYTGLIMS TRESAALRKE LLELGVSQIS AGSRTAPGGY QDSKQNQHDA 300
  301 EQFSLGDHRE MDEIIYELVT DSDAIPSFCT GCYRKGRTGD HFMGLAKQQF IGKFCQPNAL 360
  361 ITFKEYLNDY ASEKTREAGN ALIERELAKM SPSRARNVRG CLQKTDAGER DIYL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	39.39794
Match:	1oltA
Description:	Coproporphyrinogen III oxidase (HemN) from Escherichia coli is a Radical SAM enzyme.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
biotin synthase activity	2.91919723818354	bayes_pls_golite062009
radical SAM enzyme activity	2.77364380055213	bayes_pls_golite062009
sulfurtransferase activity	1.98245715445185	bayes_pls_golite062009
catalytic activity	1.85375915825216	bayes_pls_golite062009
transferase activity, transferring sulfur-containing groups	1.02075980126493	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: