YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|24374970, gi\|...
Organism:	Shewanella oneidensis MR-1
Length:	318 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|24374970, gi|....

Description	E-value	Query Range	Subject Range
gi\|68249965, gi\|... - gi\|68249965\|ref\|YP_249077.1\| thiamine-monophosphate kinase [Haemophilus influenzae 86-028NP], gi\|680...	279.0	[0..1]	[318..3]
gi\|148826047, gi... - gi\|148826047\|ref\|YP_001290800.1\| dihydrodipicolinate reductase [Haemophilus influenzae PittEE], gi\|1... gi\|229847454, gi... - gi\|229847454\|ref\|ZP_04467551.1\| dihydrodipicolinate reductase [Haemophilus influenzae 7P49H1], gi\|22... gi\|53732792 - gi\|53732792\|ref\|ZP_00349572.1\| COG0611: Thiamine monophosphate kinase [Haemophilus influenzae R2846]	279.0	[0..1]	[318..3]
gi\|36787188, gi\|... - gi\|37527752\|ref\|NP_931097.1\| thiamine monophosphate kinase [Photorhabdus luminescens subsp. laumondi...	279.0	[0..2]	[318..4]
gi\|77809762, gi\|... - gi\|77815288\|ref\|ZP_00814526.1\| Thiamine-monophosphate kinase [Shewanella putrefaciens CN-32], gi\|778...	277.0	[0..2]	[318..7]
gi\|78509071, gi\|... - gi\|78691539\|ref\|ZP_00856150.1\| Thiamine-monophosphate kinase [Shewanella sp. MR-7], gi\|78509071\|gb\|E...	277.0	[0..1]	[318..1]
gi\|120558155, gi... - gi\|82740731\|ref\|ZP_00903467.1\| Thiamine-monophosphate kinase [Shewanella sp. W3-18-1], gi\|82721951\|g...	277.0	[0..2]	[318..7]
gi\|78506488, gi\|... - gi\|78685803\|ref\|ZP_00850578.1\| Thiamine-monophosphate kinase [Shewanella sp. ANA-3], gi\|78506488\|gb\|...	277.0	[0..1]	[318..1]
gi\|1074215 - gi\|1074215\|pir\|\|E64115 thiamine-phosphate kinase (EC 2.7.4.16) - Haemophilus influenzae (strain Rd K... gi\|1574764, gi\|1... - gi\|16273217\|ref\|NP_439456.1\| thiamin-monophosphate kinase [Haemophilus influenzae Rd KW20], gi\|15747...	276.0	[0..1]	[318..20]
THIL_HAEIN - Thiamine-monophosphate kinase OS=Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) ... THIL_HAEIN - Thiamine-monophosphate kinase OS=Haemophilus influenzae GN=thiL PE=3 SV=2	276.0	[0..1]	[318..3]
gi\|77979411 - gi\|77979411\|ref\|ZP_00834830.1\| COG0611: Thiamine monophosphate kinase [Yersinia intermedia ATCC 2990...	276.0	[0..2]	[318..4]

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Predicted Domain #1

Region A:
Residues: [1-318]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKEFQLIECY FNHRGPTRRD VKLSIGDDCA LVQPAENKSI AISCDTLVEN VHFFPDIPPQ  60
   61 ALGYKALAVN LSDLAAMGAE PAWMTLALTL PEVNETWLSG FSEGLFEAAD YYGIALIGGD 120
  121 TTRGPRAINI TVHGQVPQGK ALTRHGAKAG DWIYVTGTLG DSALGLDLIR CVQHARAEHK 180
  181 EFLINRHYRP TPRVLAGQSL RSLASSAIDL SDGFISDIGH ILKASKVGAV VDVGAIPLSR 240
  241 AMQDTVSEEH ALGYALTGGE DYELLFTVPE AQKGALETAL SHAGTKFVRV GQICAGSKLK 300
  301 LQLNGELFTP PYHGFEHF

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	52.045757
Match:	1vqvA
Description:	Crystal Structure of Thiamine Monophosphate Kinase (thil) from Aquifex Aeolicus
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
cyclo-ligase activity	1.67600601239753	bayes_pls_golite062009
thiamin phosphate kinase activity	1.53327197207868	bayes_pls_golite062009
catalytic activity	0.687693392934177	bayes_pls_golite062009
phosphotransferase activity, phosphate group as acceptor	0.63318404518052	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: