YRC Public Data Repository - Protein Structure Prediction

Protein:	HIS5_SHEON
Organism:	Shewanella oneidensis MR-1
Length:	221 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HIS5_SHEON.

Description	E-value	Query Range	Subject Range
gi\|113889118, gi... - gi\|78689699\|ref\|ZP_00854357.1\| Imidazole glycerol phosphate synthase, glutamine amidotransferase sub...	180.0	[0..1]	[221..1]
gi\|117612627, gi... - gi\|78684998\|ref\|ZP_00849779.1\| Imidazole glycerol phosphate synthase, glutamine amidotransferase sub...	177.0	[0..1]	[221..1]
gi\|113884818, gi... - gi\|82496311\|ref\|ZP_00881880.1\| Imidazole glycerol phosphate synthase, glutamine amidotransferase sub...	177.0	[0..1]	[221..1]
gi\|68542298, gi\|... - gi\|68542298\|ref\|ZP_00582031.1\| Imidazole glycerol phosphate synthase, glutamine amidotransferase sub...	169.0	[0..4]	[220..32]
HIS5_PHOLL - Imidazole glycerol phosphate synthase subunit HisH OS=Photorhabdus luminescens subsp. laumondii (str... HIS5_PHOLL - Imidazole glycerol phosphate synthase subunit hisH OS=Photorhabdus luminescens subsp. laumondii GN=h...	169.0	[0..8]	[220..1]
gi\|82719742, gi\|... - gi\|82742902\|ref\|ZP_00905577.1\| Imidazole glycerol phosphate synthase, glutamine amidotransferase sub...	167.0	[0..11]	[220..30]
HIS5_BACFR - Imidazole glycerol phosphate synthase subunit HisH OS=Bacteroides fragilis (strain YCH46) GN=hisH PE... HIS5_BACFR - Imidazole glycerol phosphate synthase subunit HisH OS=Bacteroides fragilis GN=hisH PE=3 SV=1 gi\|251946286, gi... - gi\|253564821\|ref\|ZP_04842277.1\| imidazole glycerol phosphate synthase subunit hisH [Bacteroides sp. ...	167.0	[0..8]	[220..1]
gi\|77815194, gi\|... - gi\|77815194\|ref\|ZP_00814435.1\| Imidazole glycerol phosphate synthase, glutamine amidotransferase sub...	166.0	[0..11]	[220..30]
gi\|77975878 - gi\|77975878\|ref\|ZP_00831412.1\| COG0118: Glutamine amidotransferase [Yersinia frederiksenii ATCC 3364...	166.0	[0..8]	[220..1]
gi\|77962463 - gi\|77962463\|ref\|ZP_00826283.1\| COG0118: Glutamine amidotransferase [Yersinia mollaretii ATCC 43969]	166.0	[0..8]	[220..1]

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Predicted Domain #1

Region A:
Residues: [1-221]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSANTDEFDV VIIDTGCANL SSVRFAFERL GANVLVTDDK ASIKAAKRVV LPGVGSAGAA  60
   61 MASLTEKALV ELIQGLTQPV LGVCLGMQML TLLSKERGGQ ALDCQAHDCK CLGIIPTEID 120
  121 ELNSQTLKAE GLPLPHMGWN QLTFSNPSQV HPLFAGVEAG SYVYFVHSYR APLSDYTLAQ 180
  181 CRYGEDFSAA IGKDNFMGVQ FHPEKSAAVG AQILGNFLKM Q

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	28.221849
Match:	1jvnA
Description:	Cyclase subunit (or domain) of imidazoleglycerolphosphate synthase HisF; GAT subunit, HisH, (or domain) of imidazoleglycerolphosphate synthase HisF
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
imidazoleglycerol-phosphate synthase activity	8.34101262147614	bayes_pls_golite062009
ligase activity	1.70348758031146	bayes_pls_golite062009
catalytic activity	1.30391542469987	bayes_pls_golite062009
transferase activity, transferring pentosyl groups	0.643287540591989	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	0.628648036096965	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: