YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|24347835, gi\|...
Organism:	Shewanella oneidensis MR-1
Length:	346 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|24347835, gi|....

Description	E-value	Query Range	Subject Range
gi\|34496424, gi\|... - gi\|34496424\|ref\|NP_900639.1\| 4-hydroxyphenylpyruvate dioxygenase [Chromobacterium violaceum ATCC 124...	360.0	[0..2]	[346..5]
gi\|91689447, gi\|... - gi\|91785493\|ref\|YP_560699.1\| 4-hydroxyphenylpyruvate dioxygenase [Burkholderia xenovorans LB400], gi...	356.0	[0..2]	[346..4]
gi\|53720847, gi\|... - gi\|53720847\|ref\|YP_109833.1\| 4-hydroxyphenylpyruvate dioxygenase [Burkholderia pseudomallei K96243],... gi\|167904645 - gi\|167904645\|ref\|ZP_02491850.1\| 4-hydroxyphenylpyruvate dioxygenase [Burkholderia pseudomallei NCTC ... gi\|52427645, gi\|... - gi\|53724222\|ref\|YP_104120.1\| 4-hydroxyphenylpyruvate dioxygenase [Burkholderia mallei ATCC 23344], g... gi\|167912910 - gi\|167912910\|ref\|ZP_02500001.1\| 4-hydroxyphenylpyruvate dioxygenase [Burkholderia pseudomallei 112] gi\|167847691 - gi\|167847691\|ref\|ZP_02473199.1\| 4-hydroxyphenylpyruvate dioxygenase [Burkholderia pseudomallei B7210... gi\|167896264 - gi\|167896264\|ref\|ZP_02483666.1\| 4-hydroxyphenylpyruvate dioxygenase [Burkholderia pseudomallei 7894] gi\|217425738, gi... - gi\|217425738\|ref\|ZP_03457227.1\| 4-hydroxyphenylpyruvate dioxygenase [Burkholderia pseudomallei 576],... gi\|167920870 - gi\|167920870\|ref\|ZP_02507961.1\| 4-hydroxyphenylpyruvate dioxygenase [Burkholderia pseudomallei BCC21... gi\|254175180, gi... - gi\|254175180\|ref\|ZP_04881841.1\| 4-hydroxyphenylpyruvate dioxygenase [Burkholderia mallei ATCC 10399]... gi\|243062547, gi... - gi\|243062547\|gb\|EES44733.1\| 4-hydroxyphenylpyruvate dioxygenase [Burkholderia mallei PRL-20], gi\|167... gi\|167817782 - gi\|167817782\|ref\|ZP_02449462.1\| 4-hydroxyphenylpyruvate dioxygenase [Burkholderia pseudomallei 91] gi\|167826177 - gi\|167826177\|ref\|ZP_02457648.1\| 4-hydroxyphenylpyruvate dioxygenase [Burkholderia pseudomallei 9] gi\|167721605 - gi\|167721605\|ref\|ZP_02404841.1\| 4-hydroxyphenylpyruvate dioxygenase [Burkholderia pseudomallei DM98] gi\|167740578 - gi\|167740578\|ref\|ZP_02413352.1\| 4-hydroxyphenylpyruvate dioxygenase [Burkholderia pseudomallei 14] gi\|134284275, gi... - gi\|134284275\|ref\|ZP_01770965.1\| 4-hydroxyphenylpyruvate dioxygenase [Burkholderia pseudomallei 305],... gi\|124293196, gi... - gi\|124385176\|ref\|YP_001027945.1\| 4-hydroxyphenylpyruvate dioxygenase [Burkholderia mallei NCTC 10229... gi\|121229288, gi... - gi\|84521528\|ref\|ZP_01008664.1\| COG3185: 4-hydroxyphenylpyruvate dioxygenase and related hemolysins [... gi\|254192641, gi... - gi\|67758155\|ref\|ZP_00496935.1\| COG3185: 4-hydroxyphenylpyruvate dioxygenase and related hemolysins [... gi\|67734540, gi\|... - gi\|67734540\|ref\|ZP_00485666.1\| COG3185: 4-hydroxyphenylpyruvate dioxygenase and related hemolysins [... gi\|67752534, gi\|... - gi\|67752534\|ref\|ZP_00491509.1\| COG3185: 4-hydroxyphenylpyruvate dioxygenase and related hemolysins [... gi\|85066267 - gi\|85066267\|ref\|ZP_01027120.1\| COG3185: 4-hydroxyphenylpyruvate dioxygenase and related hemolysins [... gi\|76581302, gi\|... - gi\|76811849\|ref\|YP_331434.1\| 4-hydroxyphenylpyruvate dioxygenase [Burkholderia pseudomallei 1710b], ... gi\|157809806, gi... - gi\|83675951\|ref\|ZP_00937758.1\| COG3185: 4-hydroxyphenylpyruvate dioxygenase and related hemolysins [... gi\|67634516, gi\|... - gi\|67634516\|ref\|ZP_00433487.1\| COG3185: 4-hydroxyphenylpyruvate dioxygenase and related hemolysins [... gi\|194523075, gi... - gi\|83618910\|ref\|ZP_00929357.1\| COG3185: 4-hydroxyphenylpyruvate dioxygenase and related hemolysins [... gi\|83623746, gi\|... - gi\|83623746\|ref\|ZP_00934008.1\| COG3185: 4-hydroxyphenylpyruvate dioxygenase and related hemolysins [... gi\|99907424, gi\|... - gi\|99907424\|ref\|ZP_01315354.1\| hypothetical protein Bpse1_03005312 [Burkholderia pseudomallei 1655],... gi\|67680488, gi\|... - gi\|90290134\|ref\|ZP_01209810.1\| hypothetical protein Bpse17_02005160 [Burkholderia pseudomallei 1710a... gi\|67640825, gi\|... - gi\|67640825\|ref\|ZP_00439618.1\| 4-hydroxyphenylpyruvate dioxygenase [Burkholderia mallei GB8 horse 4]... gi\|226193444, gi... - gi\|226193444\|ref\|ZP_03789050.1\| 4-hydroxyphenylpyruvate dioxygenase [Burkholderia pseudomallei Pakis... gi\|126243826, gi... - gi\|67644912\|ref\|ZP_00443244.1\| COG3185: 4-hydroxyphenylpyruvate dioxygenase and related hemolysins [... gi\|237814177, gi... - gi\|237814177\|ref\|YP_002898628.1\| 4-hydroxyphenylpyruvate dioxygenase [Burkholderia pseudomallei MSHR... gi\|126228708, gi... - gi\|82527657\|ref\|ZP_00886979.1\| COG3185: 4-hydroxyphenylpyruvate dioxygenase and related hemolysins [... gi\|242315231, gi... - gi\|82533333\|ref\|ZP_00892412.1\| hypothetical protein Bpse110_02005369 [Burkholderia pseudomallei 1106...	355.0	[0..6]	[346..8]
gi\|115423952, gi... - gi\|187479365\|ref\|YP_787390.1\| 4-hydroxyphenylpyruvate dioxygenase ( hemolysin) [Bordetella avium 197...	353.0	[0..6]	[346..10]
gi\|167620762 - gi\|167620762\|ref\|ZP_02389393.1\| 4-hydroxyphenylpyruvate dioxygenase [Burkholderia thailandensis Bt4] gi\|167582649 - gi\|167582649\|ref\|ZP_02375523.1\| 4-hydroxyphenylpyruvate dioxygenase [Burkholderia thailandensis TXDO... gi\|83720009, gi\|... - gi\|83720009\|ref\|YP_443601.1\| 4-hydroxyphenylpyruvate dioxygenase [Burkholderia thailandensis E264], ...	352.0	[0..6]	[346..8]
gi\|134294416, gi... - gi\|67549551\|ref\|ZP_00427409.1\| 4-hydroxyphenylpyruvate dioxygenase [Burkholderia vietnamiensis G4], ...	351.0	[0..6]	[346..8]
gi\|194561838, gi... - gi\|84363553\|ref\|ZP_00988128.1\| COG3185: 4-hydroxyphenylpyruvate dioxygenase and related hemolysins [...	351.0	[0..6]	[346..8]
gi\|124871591, gi... - gi\|84356200\|ref\|ZP_00981057.1\| COG3185: 4-hydroxyphenylpyruvate dioxygenase and related hemolysins [... gi\|116646434, gi... - gi\|67667845\|ref\|ZP_00465053.1\| 4-hydroxyphenylpyruvate dioxygenase [Burkholderia cenocepacia HI2424]... gi\|107024329, gi... - gi\|67661102\|ref\|ZP_00458430.1\| 4-hydroxyphenylpyruvate dioxygenase [Burkholderia cenocepacia AU 1054... gi\|118714559, gi... - gi\|170731656\|ref\|YP_001763603.1\| 4-hydroxyphenylpyruvate dioxygenase [Burkholderia cenocepacia MC0-3...	350.0	[0..6]	[346..8]
VLLY_VIBVU - Hemolysin VllY OS=Vibrio vulnificus GN=vllY PE=3 SV=2 gi\|37198424, gi\|... - gi\|37679679\|ref\|NP_934288.1\| putitive hemolysin [Vibrio vulnificus YJ016], gi\|37198424\|dbj\|BAC94259.... VLLY_VIBVU - Hemolysin VllY OS=Vibrio vulnificus (strain CMCP6) GN=vllY PE=3 SV=2	349.0	[0..1]	[346..1]
gi\|207744641, gi... - gi\|207744641\|ref\|YP_002261033.1\| 4-hydroxyphenylpyruvate dioxygenase protein [Ralstonia solanacearum... gi\|83746408, gi\|... - gi\|83746408\|ref\|ZP_00943460.1\| 4-hydroxyphenylpyruvate dioxygenase [Ralstonia solanacearum UW551], g...	349.0	[0..2]	[346..4]

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Predicted Domain #1

Region A:
Residues: [1-346]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASELNPLGL LGIEFTEFAS SDTDFMHKVF IDFGFSLLKK AKNKDILYYK QNDINFLLNK  60
   61 QREGFSAKFA KSHGPAICSM GWRVEDASFA HRVAVERGAK AADDSAKDLP YPAIYGIGDS 120
  121 LIYFIDTFGA NNNIYATDFE DLSEPVITQE KGFIEVDHLT NNVYKGTMEH WANFYKNIFG 180
  181 FTEVRYFDIS GVQTALVSYA LRSPDGSFCI PINEGKGNDK NQIDEYLKEY NGPGVQHLAF 240
  241 RSRDIVKSLD AMEGSSIQCL DIIPEYYDTI FDKVPQVTEN RDRIKHHQIL VDGDESGYLL 300
  301 QIFTKNLFGP IFIEIIQRKN NLGFGEGNFT ALFQSIERDQ MRRGVL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	92.0
Match:	1cjxA
Description:	4-hydroxyphenylpyruvate dioxygenase, HppD
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
4-hydroxyphenylpyruvate dioxygenase activity	4.38224728926075	bayes_pls_golite062009
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen	2.55530845061376	bayes_pls_golite062009
oxidoreductase activity, acting on single donors with incorporation of molecular oxygen	2.50752683405128	bayes_pls_golite062009
catalytic activity	1.58822083914233	bayes_pls_golite062009
dioxygenase activity	1.00282588311932	bayes_pls_golite062009
carbon-sulfur lyase activity	0.31693173994125	bayes_pls_golite062009
lyase activity	0.06622411219947	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: