YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|24371979, gi\|...
Organism:	Shewanella oneidensis MR-1
Length:	585 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|24371979, gi|....

Description	E-value	Query Range	Subject Range
gi\|120597148, gi... - gi\|82741289\|ref\|ZP_00904014.1\| Type I restriction-modification system M subunit [Shewanella sp. W3-1...	379.0	[0..1]	[584..25]
gi\|76884668, gi\|... - gi\|77166354\|ref\|YP_344879.1\| Type I restriction-modification system M subunit [Nitrosococcus oceani ... gi\|207088960 - gi\|207088960\|gb\|EDZ66232.1\| type I restriction-modification system, M subunit [Nitrosococcus oceani ... gi\|254435849, gi... - gi\|254435849\|ref\|ZP_05049356.1\| type I restriction-modification system, M subunit [Nitrosococcus oce...	379.0	[0..1]	[584..25]
gi\|77866363, gi\|... - gi\|77954713\|ref\|ZP_00819101.1\| Type I restriction-modification system M subunit [Marinobacter aquaeo...	378.0	[0..1]	[583..25]
gi\|86145620, gi\|... - gi\|86145620\|ref\|ZP_01063950.1\| Type I restriction-modification system M subunit [Vibrio sp. MED222],...	376.0	[0..1]	[584..25]
gi\|78686851, gi\|... - gi\|78686851\|ref\|ZP_00851612.1\| Type I restriction-modification system M subunit [Shewanella sp. ANA-...	375.0	[0..1]	[584..25]
gi\|114551182, gi... - gi\|114778593\|ref\|ZP_01453420.1\| Type I restriction-modification system M subunit [Mariprofundus ferr...	373.0	[0..1]	[583..24]
gi\|88787129, gi\|... - gi\|88809187\|ref\|ZP_01124696.1\| Type I restriction-modification system M subunit [Synechococcus sp. W...	371.0	[0..1]	[584..79]
gi\|78521046, gi\|... - gi\|78701514\|ref\|ZP_00865964.1\| Type I restriction-modification system M subunit [Alkalilimnicola ehr...	332.0	[0..1]	[542..23]
gi\|27380125, gi\|... - gi\|27380125\|ref\|NP_771654.1\| type I restriction-modification system specificity subunit [Bradyrhizob...	330.0	[0..1]	[544..24]
gi\|25026813, gi\|... - gi\|25026813\|ref\|NP_736867.1\| putative restriction enzyme subunit M [Corynebacterium efficiens YS-314...	329.0	[0..1]	[565..24]

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Predicted Domain #1

Region A:
Residues: [1-489]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDASEFKDYI FGMMFLKRLS DSFDEAREQV FEYYLAKGKT QVEAEALASD EDEYDSTFYI  60
   61 PEVARWSALK DLKHNIGEAL NTAAEAIEEH NPNLEGVLVS IDFNIKNKLS DNKLRDLLSH 120
  121 FNKYRLRNSD FERPDLLGTA YEYLIKMFAD SAGKKGGEFY TPSEVVQLLV ALLKPHAGMR 180
  181 IYDPTAGSGG MLIQMRNYLA THNENAANLS LYGQEMNLNT WAICKMNMFL HGVQSADIRK 240
  241 GDTLREPKHT IDGSLMTFDR VIANPPFSLS KWGKEDCDKD KYGRFPYGTP PKDSGDLAFV 300
  301 QHMIASTNDD GMVGVVMPHG VLFRGSSEKD IRKGILEDDL LEAVISLPSG LFYGTGIPAC 360
  361 LLIINKQKPS ERQGKVLFIY AELEYHEGKN QNSLRPQDIN KIVTTFDSFS EIKRYSAVVK 420
  421 LKDIRDNDYN LNIRRYADTS PPAEIFDVRA ILHGGIPVRE VENDYIQEEI LKGFDVSCVF 480
  481 EPKLNHASQ

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	45.154902
Match:	2okcA
Description:	No description for 2okcA was found.

Predicted functions:

Term	Confidence	Notes
DNA-methyltransferase activity	7.61853880993981	bayes_pls_golite062009
site-specific DNA-methyltransferase (adenine-specific) activity	7.11249059771057	bayes_pls_golite062009
transferase activity	2.22303238506686	bayes_pls_golite062009
methyltransferase activity	1.75500643076741	bayes_pls_golite062009
S-adenosylmethionine-dependent methyltransferase activity	1.71409699782588	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	1.67663666042395	bayes_pls_golite062009
catalytic activity	1.25333584501255	bayes_pls_golite062009
DNA (cytosine-5-)-methyltransferase activity	0.937171599492037	bayes_pls_golite062009
N-methyltransferase activity	0.891400969900644	bayes_pls_golite062009
RNA methyltransferase activity	0.817509452491588	bayes_pls_golite062009
histone methyltransferase activity (H4-R3 specific)	0.647112128094373	bayes_pls_golite062009
protein-arginine omega-N symmetric methyltransferase activity	0.531263697103486	bayes_pls_golite062009
protein methyltransferase activity	0.348134584790547	bayes_pls_golite062009
rRNA methyltransferase activity	0.230719796976667	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [490-585]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STDQQYYQFK AEITTKEQIR PLVENSVEQV KAIEDCATDN SAEQTSTTEL ASVTLIVGQF  60
   61 ERWWDKYQVS LHQLDAEMAE AEQVMQGYLK ELGYES

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.828	0.093	site-specific DNA-methyltransferase (adenine-specific) activity	a.24.3	Cytochromes
View	Download	0.642	0.093	site-specific DNA-methyltransferase (adenine-specific) activity	a.24.9	alpha-catenin/vinculin
View	Download	0.722	0.093	site-specific DNA-methyltransferase (adenine-specific) activity	a.13.1	alpha-2-Macroglobulin receptor associated protein (RAP) domain 1
View	Download	0.717	0.093	site-specific DNA-methyltransferase (adenine-specific) activity	a.24.3	Cytochromes
View	Download	0.684	0.093	site-specific DNA-methyltransferase (adenine-specific) activity	a.24.3	Cytochromes

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: