YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|24115126, gi\|...
Organism:	Shigella flexneri 2a str. 301
Length:	293 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|24115126, gi|....

Description	E-value	Query Range	Subject Range
gi\|25499550, gi\|... - gi\|25499550\|pir\|\|F86070 probable enzyme Z5352 [imported] - Escherichia coli (strain O157:H7, substra... gi\|12518707, gi\|... - gi\|15804422\|ref\|NP_290462.1\| putative enzyme [Escherichia coli O157:H7 EDL933], gi\|12518707\|gb\|AAG59... gi\|13364236, gi\|... - gi\|15834014\|ref\|NP_312787.1\| hypothetical protein ECs4760 [Escherichia coli O157:H7], gi\|13364236\|db... gi\|13364236, gi\|... - gi\|15834014\|ref\|NP_312787.1\| hypothetical protein ECs4760 [Escherichia coli O157:H7 str. Sakai], gi\|...	223.0	[0..1]	[293..1]
gi\|82546183, gi\|... - gi\|82546183\|ref\|YP_410130.1\| putative enzyme [Shigella boydii Sb227], gi\|81247594\|gb\|ABB68302.1\| put...	220.0	[0..1]	[292..1]
gi\|218429682, gi... - gi\|218692118\|ref\|YP_002400330.1\| putative hydrolase [Escherichia coli ED1a], gi\|218429682\|emb\|CAR106... gi\|81343322 - gi\|81343322\|gb\|ABB71183.1\| hypothetical protein [Escherichia coli] gi\|115515228, gi... - gi\|117626104\|ref\|YP_859427.1\| putative dienelactone hydrolase [Escherichia coli APEC O1], gi\|1155152... gi\|91074946, gi\|... - gi\|91213372\|ref\|YP_543358.1\| putative carboxymethylenebutenolidase [Escherichia coli UTI89], gi\|9107... gi\|26250590, gi\|... - gi\|26250590\|ref\|NP_756630.1\| putative carboxymethylenebutenolidase [Escherichia coli CFT073], gi\|261... gi\|226903030, gi... - gi\|237702859\|ref\|ZP_04533340.1\| conserved hypothetical protein [Escherichia sp. 3_2_53FAA], gi\|22690...	217.0	[0..1]	[287..1]
gi\|75209543 - gi\|75209543\|ref\|ZP_00709764.1\| COG0412: Dienelactone hydrolase and related enzymes [Escherichia coli... gi\|75188572 - gi\|75188572\|ref\|ZP_00701839.1\| COG0412: Dienelactone hydrolase and related enzymes [Escherichia coli... gi\|75238280 - gi\|75238280\|ref\|ZP_00722279.1\| COG0412: Dienelactone hydrolase and related enzymes [Escherichia coli... gi\|75230791 - gi\|75230791\|ref\|ZP_00717254.1\| COG0412: Dienelactone hydrolase and related enzymes [Escherichia coli...	213.0	[0..5]	[293..1]
gi\|75197713 - gi\|75197713\|ref\|ZP_00707783.1\| COG0412: Dienelactone hydrolase and related enzymes [Escherichia coli...	212.0	[0..5]	[293..1]
gi\|75256246 - gi\|75256246\|ref\|ZP_00727924.1\| COG0412: Dienelactone hydrolase and related enzymes [Escherichia coli...	211.0	[0..5]	[293..1]
gi\|75512615 - gi\|75512615\|ref\|ZP_00735127.1\| COG0412: Dienelactone hydrolase and related enzymes [Escherichia coli...	210.0	[0..5]	[293..1]
gi\|81243137, gi\|... - gi\|82778989\|ref\|YP_405338.1\| putative enzyme [Shigella dysenteriae Sd197], gi\|81243137\|gb\|ABB63847.1...	210.0	[0..5]	[293..1]
gi\|83569334 - gi\|83569334\|ref\|ZP_00920789.1\| COG0412: Dienelactone hydrolase and related enzymes [Shigella dysente...	210.0	[0..5]	[292..1]
gi\|75177796 - gi\|75177796\|ref\|ZP_00697861.1\| COG0412: Dienelactone hydrolase and related enzymes [Shigella boydii ...	208.0	[0..5]	[292..1]

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Predicted Domain #1

Region A:
Residues: [1-293]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MICCMLTIVN IAQHFYKGTE NTMATTQQSG FAPAASPLAS TIVQTPDDAI VAGFTSIPSQ  60
   61 GDNMPAYHAR PKQSDGPLPV VIVVQEIFGV HEHIRDICRR LALEGYLAIA PELYFREGDP 120
  121 NDFADIPTLL SGLVAKVPDS QVLADLDHVA SWASRNGGDV HRLMITGFCW GGRITWLYAA 180
  181 HNPQLKAAVA WYGKLTGDKS LNSPKQPVDI ATDLNAPVLG LYGGQDNSIP QESVETMRQA 240
  241 LRAANAKAEI IVYPDAGHAF NADYRPSYHA ESAKDGWQRM LEWFKQYGGK KSL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	22.0
Match:	1dinA
Description:	DIENELACTONE HYDROLASE AT 2.8 ANGSTROMS
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
hydrolase activity	1.58619437002934	bayes_pls_golite062009
catalytic activity	1.39629727416851	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	0.635759022538529	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: