YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|24111928, gi\|...
Organism:	Shigella flexneri 2a str. 301
Length:	256 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|24111928, gi|....

Description	E-value	Query Range	Subject Range
gi\|1778499 - gi\|1778499\|gb\|AAB40782.1\| enterobactin synthetase component D [Escherichia coli]	279.0	[0..1]	[256..1]
gi\|26246560, gi\|... - gi\|26246560\|ref\|NP_752599.1\| phosphopantetheinyltransferase component of enterobactin synthase multi...	275.0	[0..1]	[256..1]
gi\|91071202, gi\|... - gi\|91209628\|ref\|YP_539614.1\| phosphopantetheinyltransferase component of enterobactin synthase multi... gi\|117622805, gi... - gi\|117622805\|ref\|YP_851718.1\| phosphopantetheinyltransferase component of enterobactin synthase mult...	272.0	[0..1]	[256..1]
gi\|1279837 - gi\|1279837\|gb\|AAA97936.1\| EntD	205.0	[0..48]	[256..1]
gi\|75236565 - gi\|75236565\|ref\|ZP_00720653.1\| COG2977: Phosphopantetheinyl transferase component of siderophore syn... gi\|75258680 - gi\|75258680\|ref\|ZP_00730087.1\| COG2977: Phosphopantetheinyl transferase component of siderophore syn... gi\|194413995, gi... - gi\|75210787\|ref\|ZP_00710919.1\| COG2977: Phosphopantetheinyl transferase component of siderophore syn... gi\|75227365, gi\|... - gi\|75227365\|ref\|ZP_00714143.1\| COG2977: Phosphopantetheinyl transferase component of siderophore syn... gi\|209917839, gi... - gi\|209917839\|ref\|YP_002291923.1\| phosphopantetheinyltransferase component of enterobactin synthase m... gi\|218359893, gi... - gi\|218553125\|ref\|YP_002386038.1\| phosphopantetheinyltransferase component of enterobactin synthase m... gi\|81244439, gi\|... - gi\|82543028\|ref\|YP_406975.1\| phosphopantetheinyltransferase component of enterobactin synthase multi... gi\|218694023, gi... - gi\|218694023\|ref\|YP_002401690.1\| phosphopantetheinyltransferase component of enterobactin synthase m...	202.0	[0..48]	[256..1]
gi\|82775860, gi\|... - gi\|82775860\|ref\|YP_402207.1\| phosphopantetheinyltransferase component of enterobactin synthase multi...	201.0	[0..48]	[256..1]
gi\|16128566, gi\|... - gi\|1786797\|gb\|AAC73684.1\| phosphopantetheinyltransferase component of enterobactin synthase multienz... ENTD_ECOLI - 4'-phosphopantetheinyl transferase entD (EC 2.7.8.-) (Enterobactin synthetase component D) (Enteroch... gi\|124530218, gi... - gi\|124530218\|ref\|ZP_01700967.1\| 4'-phosphopantetheinyl transferase [Escherichia coli B], gi\|12449938... gi\|194423552, gi... - gi\|83586982\|ref\|ZP_00925612.1\| COG2977: Phosphopantetheinyl transferase component of siderophore syn... gi\|238899861, gi... - gi\|238899861\|ref\|YP_002925657.1\| phosphopantetheinyltransferase component of enterobactin synthase m... gi\|188487824, gi... - gi\|75514677\|ref\|ZP_00736932.1\| COG2977: Phosphopantetheinyl transferase component of siderophore syn... gi\|251784085, gi... - gi\|251784085\|ref\|YP_002998389.1\| hypothetical protein B21_00538 [Escherichia coli BL21], gi\|24237635... gi\|89107449, gi\|... - gi\|89107449\|ref\|AP_001229.1\| phosphopantetheinyltransferase component of enterobactin synthase multi... gi\|253972564, gi... - gi\|254160663\|ref\|YP_003043771.1\| phosphopantetheinyltransferase component of enterobactin synthase m... gi\|253976758, gi... - gi\|254287451\|ref\|YP_003053199.1\| phosphopantetheinyltransferase component of enterobactin synthase m... gi\|1786797\|gb\|AA... - phosphopantetheinyltransferase component of enterobactin synthase multienzyme complex [Escherichia c... gi\|170080163, gi... - gi\|170080264\|ref\|YP_001729584.1\| phosphopantetheinyltransferase component of enterobactin synthase m... gi\|169755987, gi... - gi\|170021059\|ref\|YP_001726013.1\| phosphopantetheinyltransferase component of enterobactin synthase m...	201.0	[0..48]	[256..1]
gi\|208726103, gi... - gi\|208806302\|ref\|ZP_03248639.1\| 4'-phosphopantetheinyl transferase entD [Escherichia coli O157:H7 st... gi\|195936130 - gi\|195936130\|ref\|ZP_03081512.1\| phosphopantetheinyltransferase component of enterobactin synthase mu... gi\|208737262, gi... - gi\|208823069\|ref\|ZP_03263387.1\| 4'-phosphopantetheinyl transferase entD [Escherichia coli O157:H7 st... gi\|208815366, gi... - gi\|208815366\|ref\|ZP_03256545.1\| 4'-phosphopantetheinyl transferase entD [Escherichia coli O157:H7 st... gi\|217326521, gi... - gi\|217326521\|ref\|ZP_03442605.1\| 4'-phosphopantetheinyl transferase entD [Escherichia coli O157:H7 st... gi\|209159202, gi... - gi\|209397802\|ref\|YP_002269215.1\| 4'-phosphopantetheinyl transferase entD [Escherichia coli O157:H7 s... gi\|168754678, gi... - gi\|189358090\|gb\|EDU76509.1\| 4'-phosphopantetheinyl transferase entD [Escherichia coli O157:H7 str. E... gi\|189360860, gi... - gi\|189360860\|gb\|EDU79279.1\| 4'-phosphopantetheinyl transferase entD [Escherichia coli O157:H7 str. E... gi\|189369104, gi... - gi\|189369104\|gb\|EDU87520.1\| 4'-phosphopantetheinyl transferase entD [Escherichia coli O157:H7 str. E... gi\|209777620, gi... - pir\|\|A85557 enterobactin synthetase component D [imported] - Escherichia coli (strain O157:H7, subst... gi\|56479681, gi\|... - gi\|56479681\|ref\|NP_706438.2\| phosphopantetheinyltransferase component of enterobactin synthase multi... gi\|189003118, gi... - gi\|189003118\|gb\|EDU72104.1\| 4'-phosphopantetheinyl transferase entD [Escherichia coli O157:H7 str. E... ENTD_ECO57 - 4'-phosphopantetheinyl transferase entD OS=Escherichia coli O157:H7 GN=entD PE=3 SV=1 ENTD_SHIFL - 4'-phosphopantetheinyl transferase entD OS=Shigella flexneri GN=entD PE=3 SV=1 gi\|157065756, gi... - gi\|75194767\|ref\|ZP_00704837.1\| COG2977: Phosphopantetheinyl transferase component of siderophore syn... gi\|187769692, gi... - gi\|187769692\|gb\|EDU33536.1\| 4'-phosphopantetheinyl transferase entD [Escherichia coli O157:H7 str. E... gi\|15800297, gi\|... - gi\|15800297\|ref\|NP_286309.1\| phosphopantetheinyltransferase component of enterobactin synthase multi... gi\|189379399, gi... - gi\|189379399\|gb\|EDU97815.1\| 4'-phosphopantetheinyl transferase entD [Escherichia coli O157:H7 str. E... gi\|30040284, gi\|... - gi\|30062040\|ref\|NP_836211.1\| phosphopantetheinyltransferase component of enterobactin synthase multi... gi\|189373498, gi... - gi\|189373498\|gb\|EDU91914.1\| 4'-phosphopantetheinyl transferase entD [Escherichia coli O157:H7 str. E... gi\|13360080, gi\|... - gi\|15829876\|ref\|NP_308649.1\| phosphopantetheinyltransferase component of enterobactin synthase multi... gi\|254591149, gi... - gi\|254791749\|ref\|YP_003076586.1\| phosphopantetheinyltransferase component of enterobactin synthase m...	201.0	[0..48]	[256..1]
gi\|75177515, gi\|... - gi\|75177515\|ref\|ZP_00697596.1\| COG2977: Phosphopantetheinyl transferase component of siderophore syn...	201.0	[0..48]	[256..1]

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Predicted Domain #1

Region A:
Residues: [1-62]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRVVHAGCGV NALSGLQRSC QFNILQDHVG LISVAHQAVL RLSSVSNMVD MKTTHTSLPF  60
   61 AG

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.551	0.024	holo-[acyl-carrier-protein] synthase activity	a.24.17	Group V grass pollen allergen
View	Download	0.548	0.024	holo-[acyl-carrier-protein] synthase activity	d.52.1	Alpha-lytic protease prodomain
View	Download	0.563	0.012	holo-[acyl-carrier-protein] synthase activity	a.24.7	FKBP12-rapamycin-binding domain of FKBP-rapamycin-associated protein (FRAP)
View	Download	0.560	0.012	holo-[acyl-carrier-protein] synthase activity	a.13.1	alpha-2-Macroglobulin receptor associated protein (RAP) domain 1
View	Download	0.552	N/A	N/A	a.13.1	alpha-2-Macroglobulin receptor associated protein (RAP) domain 1

Predicted Domain #2

Region A:
Residues: [63-256]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 HTLHFVEFDP ANFCEQDLLW LPHYAQLQHA GRKRKTEHLA GRIAAVYALR EYGYKCVPAI  60
   61 GELRQPVWPA EVYGSISHCG ATALAVVSRQ PIGVDIEEIF SAQTATELTD NIITPAEHER 120
  121 LADCGLAFSL ALTLAFSAKE SAFKASEIQT DAGFLDYQII SWNKQQVIIH RENEMFAVHW 180
  181 QIKEKIVITL CQHD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	31.69897
Match:	1qr0A
Description:	4'-Phosphopantetheinyl transferase SFP
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.953339213172222	bayes_pls_golite062009
transferase activity	0.17804298348743	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.0354356597199104	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: