YRC Public Data Repository - Protein Structure Prediction

Protein:	YGK1_YEAST
Organism:	Saccharomyces cerevisiae S288c
Length:	215 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for YGK1_YEAST.

Description	E-value	Query Range	Subject Range
YGK1_YEAST - HD domain-containing protein YGL101W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YGL... YGL101W - Putative protein of unknown function; non-essential gene with similarity to YBR242W; interacts with ...	2.0E-71	[1..215]	[1..215]
YC0H_SCHPO - HD domain-containing protein C4G3.17 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPCC4... SPCC4G3.17 - HD domain	5.0E-59	[28..215]	[8..195]
gi\|18395782, gi\|... - gi\|21593302\|gb\|AAM65251.1\| unknown [Arabidopsis thaliana], gi\|21280857\|gb\|AAM45013.1\| unknown protei...	1.0E-52	[24..208]	[70..251]
gi\|12845074 - gi\|12845074\|dbj\|BAB26609.1\| unnamed protein product [Mus musculus]	2.0E-46	[35..212]	[1..175]
gi\|14521817, gi\|... - gi\|5459037\|emb\|CAB50523.1\| Metal-dependent phosphohydrolase, putative [Pyrococcus abyssi GE5], gi\|14... gi\|7518086, gi\|5... - pir\|\|E75010 hypothetical protein PAB1287 - Pyrococcus abyssi (strain Orsay), gi\|5459037\|emb\|CAB50523...	4.0E-39	[30..213]	[5..179]
gi\|7705624, gi\|4... - gi\|7705624\|ref\|NP_057147.1\| HD domain containing 2 [Homo sapiens], gi\|4929729\|gb\|AAD34125.1\|AF151888...	7.0E-39	[19..206]	[7..157]
gi\|114793629, gi... - gi\|3256738\|dbj\|BAA29421.1\| 177aa long hypothetical protein [Pyrococcus horikoshii OT3], gi\|14590259\|... gi\|114793629, gi... - pir\|\|H71141 hypothetical protein PH0347 - Pyrococcus horikoshii, gi\|114793629\|pdb\|2CQZ\|F Chain F, C...	3.0E-38	[30..211]	[5..177]
gi\|18976767, gi\|... - gi\|18976767\|ref\|NP_578124.1\| oxetanocin-like protein [Pyrococcus furiosus DSM 3638], gi\|18892358\|gb\|...	4.0E-38	[30..212]	[2..175]

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Predicted Domain #1

Region A:
Residues: [1-215]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTAVNIWKPE DNIPREILAI LSKPHPNYQL AFLNIIQLLK TQRRTGWVDH GIDPCESISD  60
   61 HMYRMGLTTM LITDKNVDRN KCIRIALVHD FAESLVGDIT PNDPMTKEEK HRREFETVKY 120
  121 LCESIIRPCS ESASREILDD WLAYEKQTCL EGRYVKDIDK YEMLVQCFEY EQKYNGKKDL 180
  181 KQFLGAINDI KTDEVKKWTQ SLLEDRQAFF DSLKE

[Run NCBI BLAST on this sequence.]

Detection Method:	Pfam
Confidence:	11.055517
Match:	PF01966
Description:	HD domain

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted functions:

Term	Confidence	Notes
binding	0.789902125235751	bayes_pls_golite062009
phosphoric ester hydrolase activity	0.745631665100501	bayes_pls_golite062009
catalytic activity	0.527877614007078	bayes_pls_golite062009
hydrolase activity, acting on ester bonds	0.494691732255975	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: