YRC Public Data Repository - Protein Structure Prediction

Protein:	MIT1_YEAST
Organism:	Saccharomyces cerevisiae S288c
Length:	666 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MIT1_YEAST.

Description	E-value	Query Range	Subject Range
YHR177W - Putative protein of unknown function; overexpression causes a cell cycle delay or arrest YHX7_YEAST - Uncharacterized protein YHR177W OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=YHR177W ...	319.0	[0..1]	[269..2]
pac2 - cAMP-independent regulatory protein Pac2 PAC2_SCHPO - cAMP-independent regulatory protein pac2 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=p...	282.0	[0..6]	[208..3]
gi\|44982648, gi\|... - gi\|45187864\|ref\|NP_984087.1\| ADL010Wp [Ashbya gossypii ATCC 10895], gi\|44982648\|gb\|AAS51911.1\| ADL01... gi\|44982648 - gi\|44982648\|gb\|AAS51911.1\| ADL010Wp [Ashbya gossypii ATCC 10895]	200.0	[0..1]	[266..1]
gi\|49091500, gi\|... - gi\|67525233\|ref\|XP_660678.1\| hypothetical protein AN3074.2 [Aspergillus nidulans FGSC A4], ref\|XP_40...	178.0	[0..6]	[220..123]
gi\|115386322, gi... - gi\|115386322\|ref\|XP_001209702.1\| conserved hypothetical protein [Aspergillus terreus NIH2624], gi\|11...	176.0	[0..3]	[238..9]
gi\|49642823, gi\|... - gi\|50307421\|ref\|XP_453689.1\| unnamed protein product [Kluyveromyces lactis], gi\|49642823\|emb\|CAH0078... gi\|49642823 - gi\|49642823\|emb\|CAH00785.1\| KLLA0D14058p [Kluyveromyces lactis]	173.0	[0..1]	[233..1]
gi\|90307686, gi\|... - gi\|90307686\|gb\|EAS37317.1\| hypothetical protein CIMG_02671 [Coccidioides immitis RS], gi\|119196593\|r... gi\|240110831 - gi\|240110831\|gb\|EER28987.1\| hypothetical protein CPC735_036930 [Coccidioides posadasii C735 delta SO...	171.0	[0..3]	[220..9]

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Predicted Domain #1

Region A:
Residues: [1-111]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDIEPTFKGY IEDEDDALLI LQATLDGKLK HIPRRPYEIE RPYLIVSGSI FVFIEEISGI  60
   61 KRWTDGVSWS PSRISGKFLI YKELDKENAG SNANATSSGS TDSAVITDGT S

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [112-249]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GARNNPSSSK IKLPPLKNHQ FDLPPTMGHS SFESEQDTSI SPSNRSNLPL KYTGLVKKTI  60
   61 SVKLKRPPFN SIENLHIVSY YSVKDIKQNC LVTPKASPFL KDVRPSQELI VAMGNTTLGN 120
  121 VKNNSTTTGN GPNNINNK

[Run NCBI BLAST on this sequence.]

Detection Method:	ab initio
Confidence:	9.16
Match:
Description:	No description for 1l8mA was found.

Predicted Domain #3

Region A:
Residues: [250-614]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNSSTPLNTV ISTNNNSANI NAAGSNQFTS ANKNYYYKND ESSGYPITQF APALPSTTLM  60
   61 YTANPPYITQ SPDNTNATGM NTHVNNNNNN SNNSSNSNNS NNNNNNNNNN NNNNNNNINN 120
  121 INNVNTNAGN GNNPNRFHNA SFAYNTTGDF INPQQQGQIS YPFYYTTIPI NNPNYYTTQP 180
  181 PNPVTNASTN ENQGYSTSST QHPYYGHPTE SQSASAAAGA TGTPGTAENV LPVSSMQPLL 240
  241 HQANNNSASS ATSTAPYPVY SMNVNVPYYN SSASAYKRAQ ENTTSNTNAE PSGATSTNSG 300
  301 TMLSNPAYAN SQYTPSQVYY QGFPQYAMAS AQNPSMYQHQ HQHPLPTVYP IATPQQNIMS 360
  361 SGHTL

[Run NCBI BLAST on this sequence.]

Detection Method:	ab initio
Confidence:	7.12
Match:
Description:	No description for 1i3qA was found.

Predicted Domain #4

Region A:
Residues: [615-666]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STIGSDPQHH HYQQEPNDHK NFAMGHANNN ILNITNNDTM NNLNTNTSTT TQ

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.894	g.41.7	Aspartate carbamoyltransferase, Regulatory-chain, C-terminal domain

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits