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View Structure Prediction Details

Protein: MUD2_YEAST
Organism: Saccharomyces cerevisiae S288c
Length: 527 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MUD2_YEAST.

Description E-value Query
Range
Subject
Range
MUD2_YEAST - Splicing factor MUD2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MUD2 PE=1 SV=3
MUD2 - Protein involved in early pre-mRNA splicing; component of the pre-mRNA-U1 snRNP complex, the commitm...
0.0 [1..527] [1..527]
gi|220953270 - gi|220953270|gb|ACL89178.1| pUf68-PB [synthetic construct]
pUf68-PF, pUf68-... - The gene poly U binding factor 68kD is referred to in FlyBase by the symbol Dmel\pUf68 (CG12085, FBg...
1.0E-30 [385..524] [406..544]
rnp-6 - RNA-binding protein status:Confirmed UniProt:Q9N3S4 protein_id:AAF60666.1
4.0E-30 [379..524] [613..748]
PUF60 - poly-U binding splicing factor 60KDa
8.0E-29 [396..524] [434..558]

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Predicted Domain #1
Region A:
Residues: [1-392]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADEKRLEDL RSKIMESIGK SEKDVVPIEN KRFNTDNAVI DTHFKRQKSD GELPKAPKSR  60
   61 NVSHSNNRGP SSIITMSTNR TTYEQTRAGP HRQSYRDASG RSYNRENRYS SHNTGPQWNN 120
  121 NPYNRQRDER RGRNERFDRR GRNGNGNYDR FNYQRKNEGS KFNGDRDKRQ LQTNKYDMNY 180
  181 NSQNVMYPGS SFDSPAYYNM ASSKANSRLV ISGLSQSSDP SIVARLKDLL ENFISGLQKT 240
  241 ESNAEDFKIS NFYIGEGRPD HIIVEFSSQI CSTMVLACRS FFNAKLGTFD LKWRRPNDYV 300
  301 QQLDHLVDFC RGTVIALENL ENIGEGEDYR MKELFSSLNV TNGTAKPLFY KCSSNTNNTG 360
  361 KESEFTKCIL LSFEVVTQDI LDKLKPYKWF KP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [393-527]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NDGKISQVTS WITFQSLPNL VTQSVRVESR VLLLLNCLDP LDLKDETFIT EIKETLKYSI  60
   61 AGADTIKICQ PGVDYRLNFE NLASGAGNIY IKFKTLEAAK HAMEELPGTQ FNDRTVLCTY 120
  121 IDEDDFDMME ATQLS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 15.522879
Match: 1jmtA_
Description: U2AF35 (35 KDa subunit)
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [416-527]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SVRVESRVLL LLNCLDPLDL KDETFITEIK ETLKYSIAGA DTIKICQPGV DYRLNFENLA  60
   61 SGAGNIYIKF KTLEAAKHAM EELPGTQFND RTVLCTYIDE DDFDMMEATQ LS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.221849
Match: 2pe8A
Description: No description for 2pe8A was found.

YRC Informatics Platform - Version 3.0
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