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View Structure Prediction Details

Protein: KRE28_YEAST
Organism: Saccharomyces cerevisiae S288c
Length: 385 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for KRE28_YEAST.

Description E-value Query
Range
Subject
Range
YDR532C - Subunit of a kinetochore-microtubule binding complex with Spc105p that bridges centromeric heterochr...
KRE28_YEAST - Spindle pole body component KRE28 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=KRE28 ...
0.0 [1..385] [1..385]
gi|13259497 - gi|13259497|ref|NP_002883.2| retinoblastoma-binding protein 1 isoform I [Homo sapiens]
2.0E-88 [16..276] [700..946]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
8.0E-84 [16..276] [363..609]

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Predicted Domain #1
Region A:
Residues: [1-131]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDTGSASIKD YETVLTDIED SIAVSSEEVL NNQELRLKNT LHEITSSILA INEENKFVNP  60
   61 LRNDESLDVE GKEVFVNPKI LSAKIKEFNK LMELLKLTYL EQETLDYFFR FTLSSTKPLQ 120
  121 LDSEKDPQFV K

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.820 0.196 spindle pole body a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.442 0.196 spindle pole body a.1.1 Globin-like
View Download 0.386 0.196 spindle pole body a.24.3 Cytochromes
View Download 0.406 0.196 spindle pole body a.80.1 DNA polymerase III clamp loader subunits, C-terminal domain
View Download 0.700 0.196 spindle pole body f.1.5 Exotoxin A, middle domain
View Download 0.363 0.196 spindle pole body a.45.1 Glutathione S-transferase (GST), C-terminal domain
View Download 0.282 0.196 spindle pole body a.7.1 Spectrin repeat
View Download 0.271 0.196 spindle pole body d.150.1 4'-phosphopantetheinyl transferase
View Download 0.255 0.196 spindle pole body a.24.3 Cytochromes
View Download 0.243 0.196 spindle pole body a.24.16 Nucleotidyltransferase substrate binding subunit/domain
View Download 0.239 0.196 spindle pole body a.24.3 Cytochromes
View Download 0.237 0.196 spindle pole body a.24.9 alpha-catenin/vinculin
View Download 0.223 0.196 spindle pole body a.121.1 Tetracyclin repressor-like, C-terminal domain
View Download 0.218 0.196 spindle pole body d.15.4 2Fe-2S ferredoxin-like
View Download 0.217 0.196 spindle pole body a.1.1 Globin-like
View Download 0.215 0.196 spindle pole body a.24.17 Group V grass pollen allergen

Predicted Domain #2
Region A:
Residues: [132-277]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LNERVNDLKE EISNVQESKI EQIKAEIQET GHNFAERQDL INELYLEATG DIENCWDSLN  60
   61 ELKNLTNKED KNMMGEKDTI LNSSDSDDFV EETYTNWQKL LFLQKQNQRL TKELKEMHEV 120
  121 KNQIIRKGEQ SKKEDSGHLM ANESEL

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [324-385]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 IAISLSDLKR PMIKDITILQ KAGGNIVTDI EASSKFNNKY RNNTKVQIFE VMDDIISELT  60
   61 NE

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.44
Match: 1qoyA
Description: Hemolysin E (HlyE, ClyA, SheA)
Matching Structure (courtesy of the PDB):

Predicted Domain #3
Region A:
Residues: [278-323]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CQSINLLTKF WEKHFLLKGS KTTILNFEIF TQLGKVQFEI KDMQYI

[Run NCBI BLAST on this sequence.]

Detection Method: ORFEUS
Confidence: 7.44
Match: 1qoyA
Description: Hemolysin E (HlyE, ClyA, SheA)
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle