YRC Public Data Repository - Protein Structure Prediction

Protein:	FNTB_YEAST
Organism:	Saccharomyces cerevisiae S288c
Length:	431 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FNTB_YEAST.

Description	E-value	Query Range	Subject Range
RAM1 - Beta subunit of the CAAX farnesyltransferase (FTase) that prenylates the a-factor mating pheromone a... FNTB_YEAST - Protein farnesyltransferase subunit beta OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN...	0.0	[1..431]	[1..431]
FNTB_BOVIN - Protein farnesyltransferase subunit beta OS=Bos taurus GN=FNTB PE=2 SV=1	0.0	[15..424]	[18..416]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	1.0E-99	[15..424]	[18..416]
ENSPTRT00000011804 - null gi\|123982626, gi... - gi\|123997291\|gb\|ABM86247.1\| farnesyltransferase, CAAX box, beta [synthetic construct], gi\|123982626\|... FNTB - farnesyltransferase, CAAX box, beta	2.0E-99	[15..424]	[18..416]
gi\|56553908 - gi\|56553908\|pdb\|1TN8\|B Chain B, Protein Farnesyltransferase Complexed With A H-Ras Peptide Substrate... FNTB_RAT - Protein farnesyltransferase subunit beta OS=Rattus norvegicus GN=Fntb PE=1 SV=1	3.0E-99	[15..424]	[18..416]
PGTB_MOUSE, PGTB... - Geranylgeranyl transferase type-2 subunit beta - Mus musculus (Mouse), Geranylgeranyl transferase ty...	4.0E-93	[71..419]	[18..331]

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Predicted Domain #1

Region A:
Residues: [1-342]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRQRVGRSIA RAKFINTALL GRKRPVMERV VDIAHVDSSK AIQPLMKELE TDTTEARYKV  60
   61 LQSVLEIYDD EKNIEPALTK EFHKMYLDVA FEISLPPQMT ALDASQPWML YWIANSLKVM 120
  121 DRDWLSDDTK RKIVDKLFTI SPSGGPFGGG PGQLSHLAST YAAINALSLC DNIDGCWDRI 180
  181 DRKGIYQWLI SLKEPNGGFK TCLEVGEVDT RGIYCALSIA TLLNILTEEL TEGVLNYLKN 240
  241 CQNYEGGFGS CPHVDEAHGG YTFCATASLA ILRSMDQINV EKLLEWSSAR QLQEERGFCG 300
  301 RSNKLVDGCY SFWVGGSAAI LEAFGYGQCF NKHALRDYIL YC

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [343-431]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CQEKEQPGLR DKPGAHSDFY HTNYCLLGLA VAESSYSCTP NDSPHNIKCT PDRLIGSSKL  60
   61 TDVNPVYGLP IENVRKIIHY FKSNLSSPS

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.364	a.3.1	Cytochrome c
View	Download	0.245	a.61.1	Retroviral matrix proteins
View	Download	0.237	d.94.1	HPr-like
View	Download	0.268	a.60.9	lambda integrase-like, N-terminal domain
View	Download	0.214	a.48.3	Conserved domain common to transcription factors TFIIS, elongin A, CRSP70
View	Download	0.204	d.58.14	Ribosomal protein S6

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits