YRC Public Data Repository - Protein Structure Prediction

Protein:	FDH1_YEAST
Organism:	Saccharomyces cerevisiae S288c
Length:	376 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FDH1_YEAST.

Description	E-value	Query Range	Subject Range
SERA_METJA - D-3-phosphoglycerate dehydrogenase OS=Methanocaldococcus jannaschii GN=serA PE=3 SV=1 SERA_METJA - D-3-phosphoglycerate dehydrogenase OS=Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / ...	0.0	[20..372]	[1..327]
GYAR_THELI - Glyoxylate reductase OS=Thermococcus litoralis GN=gyaR PE=1 SV=1 GYAR_THELN - Glyoxylate reductase OS=Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C) GN=g...	0.0	[19..371]	[1..331]
gi\|14601656, gi\|... - gi\|5105521\|dbj\|BAA80834.1\| 347aa long hypothetical D-3-phosphoglycerate dehydrogenase [Aeropyrum per... gi\|7431353 - pir\|\|E72568 probable D-3-phosphoglycerate dehydrogenase APE1831 - Aeropyrum pernix (strain K1)	0.0	[17..368]	[12..345]
gi\|22294046, gi\|... - gi\|22297868\|ref\|NP_681115.1\| D-3-phosphoglycerate dehydrogenase [Thermosynechococcus elongatus BP-1]...	0.0	[20..372]	[1..328]
GYAR_PYRFU - Glyoxylate reductase OS=Pyrococcus furiosus GN=gyaR PE=3 SV=1 GYAR_PYRFU - Glyoxylate reductase OS=Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) GN=gyaR ...	0.0	[19..359]	[1..322]
SERA_ARCFU - D-3-phosphoglycerate dehydrogenase OS=Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 /... SERA_ARCFU - D-3-phosphoglycerate dehydrogenase OS=Archaeoglobus fulgidus GN=serA PE=3 SV=1	0.0	[21..364]	[1..317]
gi\|254717444 - gi\|254717444\|ref\|ZP_05179255.1\| D-3-phosphoglycerate dehydrogenase [Brucella ceti M13/05/1] gi\|254719689 - gi\|254719689\|ref\|ZP_05181500.1\| D-3-phosphoglycerate dehydrogenase [Brucella sp. 83/13] gi\|161336427, gi... - gi\|161619616\|ref\|YP_001593503.1\| D-3-phosphoglycerate dehydrogenase [Brucella canis ATCC 23365], gi\|... gi\|148559678, gi... - gi\|148559678\|ref\|YP_001259539.1\| D-3-phosphoglycerate dehydrogenase [Brucella ovis ATCC 25840], gi\|1... gi\|23502543, gi\|... - gi\|23502543\|ref\|NP_698670.1\| D-3-phosphoglycerate dehydrogenase [Brucella suis 1330], gi\|23348542\|gb... gi\|254708447 - gi\|254708447\|ref\|ZP_05170275.1\| D-3-phosphoglycerate dehydrogenase [Brucella pinnipedialis M163/99/1... gi\|254714547 - gi\|254714547\|ref\|ZP_05176358.1\| D-3-phosphoglycerate dehydrogenase [Brucella ceti M644/93/1] gi\|254703466 - gi\|254703466\|ref\|ZP_05165294.1\| D-3-phosphoglycerate dehydrogenase [Brucella suis bv. 3 str. 686]	0.0	[19..370]	[1..326]
gi\|25283945 - pir\|\|AG3295 phosphoglycerate dehydrogenase (EC 1.1.1.95) [imported] - Brucella melitensis (strain 16... gi\|17986632, gi\|... - gi\|17986632\|ref\|NP_539266.1\| D-3-phosphoglycerate dehydrogenase [Brucella melitensis 16M], gi\|179822...	0.0	[17..370]	[4..331]
gi\|25283944, gi\|... - pir\|\|AF3012 D-3-phosphoglycerate dehydrogenase serA [imported] - Agrobacterium tumefaciens (strain C... gi\|17937411, gi\|... - gi\|17937411\|ref\|NP_534200.1\| D-3-phosphoglycerate dehydrogenase [Agrobacterium tumefaciens str. C58]...	0.0	[19..370]	[1..326]
gi\|7431368 - gi\|7431368\|pir\|\|H69229 phosphoglycerate dehydrogenase - Methanobacterium thermoautotrophicum (strain... SERA_METTH - D-3-phosphoglycerate dehydrogenase OS=Methanothermobacter thermautotrophicus (strain ATCC 29096 / DS...	0.0	[20..372]	[3..328]

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Predicted Domain #1

Region A:
Residues: [1-123]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKGKVLLVL YEGGKHAEEQ EKLLGCIENE LGIRNFIEEQ GYELVTTIDK DPEPTSTVDR  60
   61 ELKDAEIVIT TPFFPAYISR NRIAEAPNLK LCVTAGVGSD HVDLEAANER KITVTEVTGS 120
  121 NVV

[Run NCBI BLAST on this sequence.]

Region B:
Residues: [327-376]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SGTSLDAQKR YAQGVKNILN SYFSKKFDYR PQDIIVQNGS YATRAYGQKK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	953.218487
Match:	2nacA_
Description:	Formate dehydrogenase
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [124-326]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SVAEHVMATI LVLIRNYNGG HQQAINGEWD IAGVAKNEYD LEDKIISTVG AGRIGYRVLE  60
   61 RLVAFNPKKL LYYDYQELPA EAINRLNEAS KLFNGRGDIV QRVEKLEDMV AQSDVVTINC 120
  121 PLHKDSRGLF NKKLISHMKD GAYLVNTARG AICVAEDVAE AVKSGKLAGY GGDVWDKQPA 180
  181 PKDHPWRTMD NKDHVGNAMT VHI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	953.218487
Match:	2nacA_
Description:	Formate dehydrogenase
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits