YRC Public Data Repository - Protein Structure Prediction

Protein:	MIC60_YEAST
Organism:	Saccharomyces cerevisiae S288c
Length:	540 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MIC60_YEAST.

Description	E-value	Query Range	Subject Range
MIC60_YEAST - MICOS complex subunit MIC60 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MIC60 PE=1 S... FCJ1 - Mitochondrial inner membrane protein involved in formation and molecular structure of crista junctio...	1.0E-63	[1..540]	[1..540]
gi\|3668187 - gi\|3668187\|dbj\|BAA33452.1\| myosin heavy chain [Theragra chalcogramma]	8.0E-59	[32..468]	[800..1286]
MYH4_PIG - Myosin-4 OS=Sus scrofa GN=MYH4 PE=2 SV=1	1.0E-47	[32..459]	[800..1276]
gi\|7507776 - gi\|7507776\|pir\|\|T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans	4.0E-47	[31..469]	[13..511]
gi\|179508, gi\|10... - sp\|P12883\|MYH7_HUMAN Myosin heavy chain, cardiac muscle beta isoform (MyHC-beta), gi\|4557773\|ref\|NP...	7.0E-47	[31..469]	[797..1295]
MYH7_BOVIN - Myosin-7 OS=Bos taurus GN=MYH7 PE=1 SV=1	3.0E-46	[32..469]	[798..1295]

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Predicted Domain #1

Region A:
Residues: [1-377]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMLRTTASRK IVLRRGLASI NTGTTVASKK ASHKFRNTLW TIALSATAFY AGGIIYSQKN  60
   61 DKFGDFFSNN VPFAEDLLET YEHYHDRPTL FLEDSWDGLK AKSNDLLSGL TGSSQTRRSN 120
  121 RENIEVKKIL SLEPLNIETE NSDPQLKEII GSLNDLINSL NDSNLSIPES EFNSIKKSNQ 180
  181 NMLTNLSQLN ETLKEALSNY MIQRTSEVIT ELNTQYENSK REFEKNLQKN LLQEVDEFKE 240
  241 NLTKQKDKEL EEKLKANEEL LQAKHANEVG LLSITQVKEF NKIIKDKIEK ERNGRLAHLE 300
  301 EINSEVNDLS KSIDRSSKIL SKNEALVQLT FQVDEIKSRI NNNNLPDVNI DKELSRLKLL 360
  361 SNLLSTFNKK SCCDDGD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	35.154902
Match:	1i84S_
Description:	Heavy meromyosin subfragment
Matching Structure (courtesy of the PDB):

Predicted Domain #2

Region A:
Residues: [378-540]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CCSCKKGNKN EGKEGKISCK CKPKTNPPSL LSVALDELES TCSGKKILSN EQIYNRWNLL  60
   61 ADDFKTASLL PPNSGILGQL TAKVFSLFLF TKTGNPSNAT DFDSVYARVG DNLRVSNLND 120
  121 AVEEVVSLKG WPHKVCESWI EDARRKLEVQ RLVEILDCEI RTL

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3

Region A:
Residues: [472-540]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NPSNATDFDS VYARVGDNLR VSNLNDAVEE VVSLKGWPHK VCESWIEDAR RKLEVQRLVE  60
   61 ILDCEIRTL

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits