YRC Public Data Repository - Protein Structure Prediction

Protein:	ARGJ_YEAST
Organism:	Saccharomyces cerevisiae S288c
Length:	441 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ARGJ_YEAST.

Description	E-value	Query Range	Subject Range
ARG7 - Mitochondrial ornithine acetyltransferase, catalyzes the fifth step in arginine biosynthesis; also p... ARGJ_YEAS1 - Arginine biosynthesis bifunctional protein ArgJ, mitochondrial OS=Saccharomyces cerevisiae (strain R... ARGJ_YEAS6 - Arginine biosynthesis bifunctional protein ArgJ, mitochondrial OS=Saccharomyces cerevisiae (strain A... ARGJ_YEAS2 - Arginine biosynthesis bifunctional protein ArgJ, mitochondrial OS=Saccharomyces cerevisiae (strain J... ARGJ_YEAS7 - Arginine biosynthesis bifunctional protein ArgJ, mitochondrial OS=Saccharomyces cerevisiae (strain Y... ARGJ_YEAST - Arginine biosynthesis bifunctional protein ArgJ, mitochondrial OS=Saccharomyces cerevisiae (strain A...	0.0	[1..441]	[1..441]
ARGJ_BACAM - Arginine biosynthesis bifunctional protein ArgJ OS=Bacillus amyloliquefaciens GN=argJ PE=3 SV=1 ARGJ_BACSU - Arginine biosynthesis bifunctional protein ArgJ OS=Bacillus subtilis GN=argJ PE=3 SV=2 gi\|221322483 - gi\|221322483\|ref\|ZP_03603777.1\| bifunctional ornithine acetyltransferase/N-acetylglutamate synthase ... ARGJ_BACSU - Arginine biosynthesis bifunctional protein ArgJ OS=Bacillus subtilis (strain 168) GN=argJ PE=3 SV=2 gi\|221318209 - gi\|221318209\|ref\|ZP_03599503.1\| bifunctional ornithine acetyltransferase/N-acetylglutamate synthase ... gi\|221313285 - gi\|221313285\|ref\|ZP_03595090.1\| bifunctional ornithine acetyltransferase/N-acetylglutamate synthase ...	0.0	[13..441]	[3..406]
ARGJ_GEOSE - Arginine biosynthesis bifunctional protein ArgJ OS=Geobacillus stearothermophilus GN=argJ PE=1 SV=1	0.0	[23..441]	[15..410]
ARGJ_THEMA - Arginine biosynthesis bifunctional protein ArgJ OS=Thermotoga maritima GN=argJ PE=3 SV=1 ARGJ_THEMA - Arginine biosynthesis bifunctional protein ArgJ OS=Thermotoga maritima (strain ATCC 43589 / MSB8 / D...	0.0	[28..441]	[3..397]
gi\|16078185, gi\|... - gi\|2633457\|emb\|CAB12961.1\| amino-acid acetyltransferase; ornithine acetyltransferase [Bacillus subti... ARGJ_BACSU - Arginine biosynthesis bifunctional protein argJ OS=Bacillus subtilis GN=argJ PE=3 SV=1	0.0	[13..441]	[3..406]
gi\|7448559 - pir\|\|S75647 glutamate N-acetyltransferase (EC 2.3.1.35) - Synechocystis sp. (strain PCC 6803) gi\|1653293, gi\|1... - gi\|1653293\|dbj\|BAA18208.1\| ornithine acetyltransferase [Synechocystis sp. PCC 6803], gi\|16330800\|ref...	0.0	[22..441]	[13..419]
ARGJ_THENE - Arginine biosynthesis bifunctional protein argJ OS=Thermotoga neapolitana GN=argJ PE=1 SV=1	0.0	[29..441]	[4..397]
gi\|224501470 - gi\|224501470\|ref\|ZP_03669777.1\| bifunctional ornithine acetyltransferase/N-acetylglutamate synthase ... ARGJ_LISMO - Arginine biosynthesis bifunctional protein ArgJ OS=Listeria monocytogenes GN=argJ PE=3 SV=1 ARGJ_LISMO - Arginine biosynthesis bifunctional protein ArgJ OS=Listeria monocytogenes serovar 1/2a (strain ATCC ...	0.0	[22..441]	[4..398]
ARGJ_LISIN - Arginine biosynthesis bifunctional protein ArgJ OS=Listeria innocua serovar 6a (strain CLIP 11262) G... ARGJ_LISIN - Arginine biosynthesis bifunctional protein ArgJ OS=Listeria innocua GN=argJ PE=3 SV=1	0.0	[22..441]	[4..398]

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Predicted Domain #1

Region A:
Residues: [1-358]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRISSTLLQR SKQLIDKYAL YVPKTGSFPK GFEVGYTASG VKKNGSLDLG VILNTNKSRP  60
   61 STAAAVFTTN KFKAAPVLTS KKVLETARGK NINAIVVNSG CANSVTGDLG MKDAQVMIDL 120
  121 VNDKIGQKNS TLVMSTGVIG QRLQMDKIST GINKIFGEEK FGSDFNSWLN VAKSICTTDT 180
  181 FPKLVTSRFK LPSGTEYTLT GMAKGAGMIC PNMATLLGFI VTDLPIESKA LQKMLTFATT 240
  241 RSFNCISVDG DMSTNDTICM LANGAIDTKE INEDSKDFEQ VKLQVTEFAQ RLAQLVVRDG 300
  301 EGSTKFVTVN VKNALHFEDA KIIAESISNS MLVKTALYGQ DANWGRILCA IGYAKLND

[Run NCBI BLAST on this sequence.]

Detection Method:	ORFEUS
Confidence:	8.98
Match:	1b65A
Description:	L-aminopeptidase D-Ala-esterase/amidase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
glutamate N-acetyltransferase activity	7.31583566409397	bayes_pls_golite062009
acetyl-CoA:L-glutamate N-acetyltransferase activity	5.4926416554153	bayes_pls_golite062009
N-acetyltransferase activity	4.96696522207886	bayes_pls_golite062009
N-acyltransferase activity	4.73607169922009	bayes_pls_golite062009
transferase activity, transferring acyl groups	3.68873019774933	bayes_pls_golite062009
acetyltransferase activity	2.5583016526898	bayes_pls_golite062009
catalytic activity	1.79436687732784	bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups	1.59037053975861	bayes_pls_golite062009
acyltransferase activity	1.58751303684177	bayes_pls_golite062009
transferase activity	1.00050620701588	bayes_pls_golite062009

Predicted Domain #2

Region A:
Residues: [359-441]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LKSLDVNKIN VSFIATDNSE PRELKLVANG VPQLEIDETR ASEILALNDL EVSVDLGTGD  60
   61 QAAQFWTCDL SHEYVTINGD YRS

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: