YRC Public Data Repository - Protein Structure Prediction

Protein:	ACA1_YEAST
Organism:	Saccharomyces cerevisiae S288c
Length:	489 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ACA1_YEAST.

Description	E-value	Query Range	Subject Range
ACA1 - Basic leucine zipper (bZIP) transcription factor of the ATF/CREB family, may regulate transcription ... ACA1_YEAST - ATF/CREB activator 1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=ACA1 PE=2 SV=1	0.0	[1..489]	[1..489]
cas-1 - adenylyl cyclase-associated protein status:Partially_confirmed UniProt:Q95YA9 protein_id:AAK85481.1	0.0	[20..368]	[387..732]
gi\|4218470 - gi\|4218470\|emb\|CAA75757.1\| c-fos [Ovis aries] gi\|4495251 - gi\|4495251\|emb\|CAB39278.1\| c-fos [Sus scrofa]	0.002	[392..474]	[1..83]
FOSX_MSVFR - Transforming protein v-Fos/v-Fox OS=FBR murine osteosarcoma virus GN=FOS-FOX PE=3 SV=1	0.005	[386..474]	[115..203]
gi\|2801478, gi\|9... - gi\|9626985\|ref\|NP_056890.1\| gag polyprotein [Murine osteosarcoma virus], gi\|2801478\|gb\|AAC82572.1\| p... gi\|332196 - gi\|332196\|gb\|AAA46573.1\| gag-fos fusion protein [FBR murine osteosarcoma virus]	0.009	[386..474]	[425..513]

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Predicted Domain #1

Region A:
Residues: [1-121]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDYKHNFATS PDSFLDGRQN PLLYTDFLSS NKELIYKQPS GPGLVDSAYN FHHQNSLHDR  60
   61 SVQENLGPMF QPFGVDISHL PITNPPIFQS SLPAFDQPVY KRRISISNGQ ISQLGEDLET 120
  121 V

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.279	d.87.2	CO dehydrogenase flavoprotein C-terminal domain-like
View	Download	0.279	d.87.2	CO dehydrogenase flavoprotein C-terminal domain-like

Predicted Domain #2

Region A:
Residues: [122-384]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ENLYNCQPPI LSSKAQQNPN PQQVANPSAA IYPSFSSNEL QNVPQPHEQA TVIPEAAPQT  60
   61 GSKNIYAAMT PYDSNIKLNI PAVAATCDIP SATPSIPSGD STMNQAYINM QLRLQAQMQT 120
  121 KAWKNAQLNV HPCTPASNSS VSSSSSCQNI NDHNIENQSV HSSISHGVNH HTVNNSCQNA 180
  181 ELNISSSLPY ESKCPDVNLT HANSKPQYKD ATSALKNNIN SEKDVHTAPF SSMHTTATFQ 240
  241 IKQEARPQKI ENNTAGLKDG AKA

[Run NCBI BLAST on this sequence.]

Detection Method:	ORFEUS
Confidence:	7.18
Match:	1i3qA
Description:	RBP1
Matching Structure (courtesy of the PDB):

Predicted Domain #3

Region A:
Residues: [385-489]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WKRARLLERN RIAASKCRQR KKMSQLQLQR EFDQISKENT MMKKKIENYE KLVQKMKKIS  60
   61 RLHMQECTIN GGNNSYQSLQ NKDSDVNGFL KMIEEMIRSS SLYDE

[Run NCBI BLAST on this sequence.]

Detection Method:	ORFEUS
Confidence:	11.54
Match:	1fosH
Description:	C-jun
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits