YRC Public Data Repository - Protein Structure Prediction

Protein:	SAC5_ARATH
Organism:	Arabidopsis thaliana
Length:	785 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SAC5_ARATH.

Description	E-value	Query Range	Subject Range
gi\|28923339, gi\|... - gi\|32418670\|ref\|XP_329813.1\| hypothetical protein [Neurospora crassa], gi\|28923339\|gb\|EAA32532.1\| hy... gi\|85104596 - gi\|85104596\|ref\|XP_961768.1\| hypothetical protein [Neurospora crassa OR74A]	736.0	[0..6]	[778..139]
gi\|38111109, gi\|... - gi\|39971551\|ref\|XP_367166.1\| hypothetical protein MGG_07091 [Magnaporthe grisea 70-15], gb\|EAA56736....	708.0	[0..12]	[778..143]
gi\|71002640, gi\|... - gi\|71002640\|ref\|XP_756001.1\| polyphosphoinositide phosphatase Fig4 [Aspergillus fumigatus Af293], gi...	705.0	[0..2]	[780..122]
gi\|167830421, gi... - gi\|167830421\|ref\|NP_001108096.1\| FIG4 homolog [Pan troglodytes], gi\|114608993\|ref\|XP_518683.2\| PREDI...	703.0	[0..15]	[736..95]
gi\|116195952, gi... - gi\|88180487\|gb\|EAQ87955.1\| hypothetical protein CHGG_04574 [Chaetomium globosum CBS 148.51], gi\|1161...	700.0	[0..2]	[761..129]
gi\|73973735, gi\|... - gi\|73973735\|ref\|XP_532259.2\| PREDICTED: similar to SAC domain-containing protein 3 isoform 1 [Canis ...	700.0	[0..9]	[736..2]
FIG4_MOUSE - Polyphosphoinositide phosphatase OS=Mus musculus GN=Fig4 PE=1 SV=1	699.0	[0..9]	[736..2]
gi\|92096743, gi\|... - gi\|92096743\|gb\|AAI14695.1\| FIG4 homolog (S. cerevisiae) [Bos taurus], gi\|115496568\|ref\|NP_001069482....	697.0	[0..9]	[736..2]
gi\|49106705, gi\|... - gi\|67900654\|ref\|XP_680583.1\| hypothetical protein AN7314.2 [Aspergillus nidulans FGSC A4], ref\|XP_41...	697.0	[0..14]	[780..142]

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Predicted Domain #1

Region A:
Residues: [1-190]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGSEPRFEPR PELIDLPVLQ KFKLYATPSN FYLIGRDENK SFRRILKIDR RDQNELNLFE  60
   61 DPTRYTKDEM RELKRRMIVG NEESGGFKAI TTCYGIIGFV RFLEPYYMLL ITKRKKVGEI 120
  121 CGHTVYGIAE SQMIAIPHPS IQSKVAKSEA ELRYKKLLSV VDLSKNFYFS YTYHLMYSLQ 180
  181 KNIGNTERGN

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [191-265]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PHDNTMFVWN SFLTREIRKI LQNSIWTVAL IYGFFQQTKC SVSGEKFVFT IIARRSRHYA  60
   61 GTRYLRRGVN DIGRV

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.932	N/A	N/A	d.204.1	Ribosome binding protein Y (YfiA homologue)
View	Download	0.839	N/A	N/A	c.47.2	RNA 3'-terminal phosphate cyclase, RPTC, insert domain
View	Download	0.839	N/A	N/A	c.47.2	RNA 3'-terminal phosphate cyclase, RPTC, insert domain
View	Download	0.717	N/A	N/A	d.50.2	Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain
View	Download	0.686	N/A	N/A	d.50.2	Porphobilinogen deaminase (hydroxymethylbilane synthase), C-terminal domain
View	Download	0.640	N/A	N/A	d.17.3	Disulfide bond isomerase, DsbC, N-terminal domain
View	Download	0.561	N/A	N/A	c.47.2	RNA 3'-terminal phosphate cyclase, RPTC, insert domain

Predicted Domain #3

Region A:
Residues: [266-351]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ANDVETEQIV SKVVPAGQKI PITSVVQVRG SIPLFWSQEA SVFNPQPEII LNKKDANYEA  60
   61 TQHHFQNLRQ RYGNRIIILN LLKTVT

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.877	d.58.18	Regulatory domain in the aminoacid metabolism
View	Download	0.859	d.58.18	Regulatory domain in the aminoacid metabolism
View	Download	0.787	d.58.18	Regulatory domain in the aminoacid metabolism
View	Download	0.782	d.58.4	Dimeric alpha+beta barrel
View	Download	0.763	d.52.8	Description not found.
View	Download	0.751	d.58.12	eEF-1beta-like
View	Download	0.694	d.58.12	eEF-1beta-like
View	Download	0.675	c.52.2	tRNA splicing endonuclease, C-terminal domain
View	Download	0.633	d.58.18	Regulatory domain in the aminoacid metabolism
View	Download	0.609	d.58.18	Regulatory domain in the aminoacid metabolism

Predicted Domain #4

Region A:
Residues: [352-457]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GEKKHRETIL RGEFAKTIRF INKGMDREHR LKAIHFDLSK HYKKGADGAF NHLCIFSRKS  60
   61 LELTDLFYCK APSGVGAEEV IYDSFFNNPI PSQDEEASSP EKEDMK

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.814	N/A	N/A	a.24.17	Group V grass pollen allergen
View	Download	0.814	N/A	N/A	a.24.17	Group V grass pollen allergen
View	Download	0.608	N/A	N/A	a.186.1	Description not found.
View	Download	0.593	N/A	N/A	a.8.9	Description not found.
View	Download	0.526	N/A	N/A	a.8.3	Families 57/38 glycoside transferase middle domain
View	Download	0.517	N/A	N/A	a.4.5	"Winged helix" DNA-binding domain
View	Download	0.517	N/A	N/A	a.4.5	"Winged helix" DNA-binding domain
View	Download	0.515	N/A	N/A	a.4.5	"Winged helix" DNA-binding domain
View	Download	0.437	N/A	N/A	a.4.5	"Winged helix" DNA-binding domain

Predicted Domain #5

Region A:
Residues: [458-596]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ADIFLLQNGV LRTNCIDCLD RTNFAQYAHG LVSLGHQLRT LGISGPPVVD LNNPLAIELM  60
   61 DAYQKMGNTL AMQYGGSEAH SKMFCDLRGN WNMVMRQRDI FTAVRRYYSN AYQDSDKQNA 120
  121 INVFLGHFRP RLGRPALWE

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.555	N/A	N/A	a.1.1	Globin-like
View	Download	0.555	N/A	N/A	a.1.1	Globin-like
View	Download	0.508	N/A	N/A	a.24.3	Cytochromes
View	Download	0.508	N/A	N/A	a.24.3	Cytochromes
View	Download	0.504	N/A	N/A	a.24.3	Cytochromes
View	Download	0.504	N/A	N/A	a.24.3	Cytochromes
View	Download	0.498	N/A	N/A	a.24.9	alpha-catenin/vinculin
View	Download	0.490	N/A	N/A	a.24.3	Cytochromes
View	Download	0.434	N/A	N/A	a.45.1	Glutathione S-transferase (GST), C-terminal domain

Predicted Domain #6

Region A:
Residues: [597-785]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LDSDQHNIGR SGSNLDIENM RPLIRRSFSD NIIMDCDLNL EELVRENSQP TYEGLNGGVS  60
   61 GTNLEFPFYE TEPASLSFLS VMRNEELMRE TGSGQMFQGS SSNSDSHRPN DIPGFSHSYV 120
  121 TKFTPAEDIF ERGSSKSVSS DNLFTDRDES VTSLTNTNSS FEFPIMGGSD LLPGFSNAFA 180
  181 RWVFSARAW

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	9.221849
Match:	1i9yA
Description:	Synaptojanin, IPP5C domain
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits