YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|20808610, gi\|...
Organism:	Thermoanaerobacter tengcongensis MB4
Length:	263 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|20808610, gi|....

Description	E-value	Query Range	Subject Range
gi\|149948927, gi... - gi\|77686688\|ref\|ZP_00802021.1\| Phosphomethylpyrimidine kinase [Alkaliphilus metalliredigenes QYMF], ...	241.0	[0..1]	[259..1]
gi\|28211403, gi\|... - gi\|28211403\|ref\|NP_782347.1\| hydroxymethylpyrimidine kinase [Clostridium tetani E88], gi\|28203844\|gb...	240.0	[0..1]	[259..7]
gi\|106895590, gi... - gi\|158321715\|ref\|YP_001514222.1\| phosphomethylpyrimidine kinase [Alkaliphilus oremlandii OhILAs], gi...	240.0	[0..1]	[258..1]
gi\|255517037 - gi\|255517037\|ref\|ZP_05384713.1\| putative phosphomethylpyrimidine kinase [Clostridium difficile QCD-9... gi\|255650139 - gi\|255650139\|ref\|ZP_05397041.1\| putative phosphomethylpyrimidine kinase [Clostridium difficile QCD-3... gi\|115250640, gi... - gi\|126699203\|ref\|YP_001088100.1\| putative phosphomethylpyrimidine kinase [Clostridium difficile 630]... gi\|254975231 - gi\|254975231\|ref\|ZP_05271703.1\| putative phosphomethylpyrimidine kinase [Clostridium difficile QCD-6... gi\|255092621 - gi\|255092621\|ref\|ZP_05322099.1\| putative phosphomethylpyrimidine kinase [Clostridium difficile CIP 1... gi\|255100727 - gi\|255100727\|ref\|ZP_05329704.1\| putative phosphomethylpyrimidine kinase [Clostridium difficile QCD-6... gi\|255314358 - gi\|255314358\|ref\|ZP_05355941.1\| putative phosphomethylpyrimidine kinase [Clostridium difficile QCD-7...	233.0	[0..5]	[260..9]
gi\|110802744, gi... - gi\|110802744\|ref\|YP_698658.1\| phosphomethylpyrimidine kinase [Clostridium perfringens SM101], gi\|110...	229.0	[0..3]	[257..6]
gi\|18145000, gi\|... - gi\|18310320\|ref\|NP_562254.1\| phosphomethylpyrimidine kinase [Clostridium perfringens str. 13], gi\|18...	226.0	[0..3]	[257..6]
gi\|110674810, gi... - gi\|110800163\|ref\|YP_695988.1\| phosphomethylpyrimidine kinase [Clostridium perfringens ATCC 13124], g...	225.0	[0..3]	[257..6]
gi\|89333599, gi\|... - gi\|89894151\|ref\|YP_517638.1\| hypothetical protein DSY1405 [Desulfitobacterium hafniense Y51], gi\|893...	225.0	[0..1]	[259..1]
gi\|27468610, gi\|... - gi\|27468610\|ref\|NP_765247.1\| phosphomethylpyrimidine kinase [Staphylococcus epidermidis ATCC 12228],... gi\|57638290, gi\|... - gi\|57867632\|ref\|YP_189265.1\| phosphomethylpyrimidine kinase [Staphylococcus epidermidis RP62A], gi\|5...	224.0	[0..2]	[260..5]
gi\|219538811, gi... - gi\|68208946\|ref\|ZP_00561025.1\| Phosphomethylpyrimidine kinase [Desulfitobacterium hafniense DCB-2], ...	224.0	[0..1]	[259..1]

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Predicted Domain #1

Region A:
Residues: [1-263]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLALTIAGS DSGGGAGIQA DLKTFSAHGV FGMSVITSIT AQNTMGVLGI EDVSPDMVYL  60
   61 QMRAIFEDLY PDAVKIGMVS NEEIIKTIAK GLKEYGVEKV VLDPVMIAKS GDPLLKPEAM 120
  121 KALKEELLPL SLVVTPNLME AKELTGMEIK NISDMKEAAK KILSLGAKVV LVKGGHLEGE 180
  181 AVDVFYDGVE FYEIKAERIN TKNTHGTGCT FSSAIAANLA LGYDLLEAVK RAKRYITGAI 240
  241 KNSLSIGHGV GPTNHFWNVE FKE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	49.69897
Match:	1jxhA
Description:	4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate kinase (HMP-phosphate kinase, ThiD)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
phosphomethylpyrimidine kinase activity	4.17236703133163	bayes_pls_golite062009
phosphotransferase activity, phosphate group as acceptor	2.49796023165143	bayes_pls_golite062009
catalytic activity	2.11518580948187	bayes_pls_golite062009
transferase activity	1.65599843675995	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	1.53929419091344	bayes_pls_golite062009
kinase activity	1.44909019943198	bayes_pls_golite062009
thiamin-phosphate diphosphorylase activity	1.41576214895876	bayes_pls_golite062009
hydroxyethylthiazole kinase activity	0.44128654727966	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: