YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|20516345, gi\|...
Organism:	Thermoanaerobacter tengcongensis MB4
Length:	274 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|20516345, gi|....

Description	E-value	Query Range	Subject Range
gi\|20807665, gi\|... - gi\|20807665\|ref\|NP_622836.1\| 2-oxoglutarate ferredoxin oxidoreductase subunit beta [Thermoanaerobact... gi\|20807665 - gi\|20807665\|ref\|NP_622836.1\| ferrodoxin oxidoreductase beta subunit [Thermoanaerobacter tengcongensi...	234.0	[0..1]	[270..1]
gi\|110602061, gi... - gi\|222055756\|ref\|YP_002538118.1\| thiamine pyrophosphate protein domain protein TPP-binding [Geobacte...	227.0	[0..7]	[270..6]
gi\|18893947, gi\|... - gi\|18978144\|ref\|NP_579501.1\| 2-oxoglutarate ferredoxin oxidoreductase subunit beta [Pyrococcus furio...	226.0	[0..2]	[271..6]
gi\|88914985, gi\|... - gi\|88938272\|ref\|ZP_01143748.1\| keto/oxoacid ferredoxin oxidoreductase, beta subunit [Geobacter urani...	226.0	[0..7]	[270..6]
gi\|5457940, gi\|1... - gi\|5457940\|emb\|CAB49430.1\| korB-2 2-ketoglutarate ferredoxin oxidoreductase, subunit beta [Pyrococcu... gi\|5457940, gi\|7... - pir\|\|G75168 2-ketoglutarate ferredoxin oxidoreductase, chain beta (korb-2) PAB0347 - Pyrococcus aby...	226.0	[0..2]	[271..6]
gi\|158140801, gi... - gi\|158320602\|ref\|YP_001513109.1\| 2-oxoglutarate ferredoxin oxidoreductase subunit beta [Alkaliphilus...	225.0	[0..1]	[271..1]
gi\|14591430, gi\|... - gi\|3258090\|dbj\|BAA30773.1\| 281aa long hypothetical ferredoxin oxidoreductase beta subunit [Pyrococcu... gi\|7431591 - pir\|\|E71046 probable ferredoxin oxidoreductase beta subunit - Pyrococcus horikoshii	224.0	[0..2]	[271..6]
gi\|166856398, gi... - gi\|76796390\|ref\|ZP_00778753.1\| Thiamine pyrophosphate enzyme, C-terminal TPP-binding [Thermoanaeroba... gi\|242256657, gi... - gi\|242256657\|ref\|ZP_04801544.1\| thiamine pyrophosphate protein domain protein TPP-binding [Thermoana... gi\|241902747, gi... - gi\|241902747\|ref\|ZP_04787478.1\| thiamine pyrophosphate protein domain protein TPP-binding [Thermoana... gi\|166854466, gi... - gi\|167040226\|ref\|YP_001663211.1\| 2-oxoglutarate ferredoxin oxidoreductase subunit beta [Thermoanaero...	224.0	[0..1]	[270..1]
gi\|77638153, gi\|... - gi\|77686069\|ref\|ZP_00801441.1\| Thiamine pyrophosphate enzyme, C-terminal TPP-binding [Alkaliphilus m...	224.0	[0..1]	[271..1]
KORB_METJA - 2-oxoglutarate synthase subunit korB OS=Methanocaldococcus jannaschii GN=korB PE=4 SV=1 KORB_METJA - 2-oxoglutarate synthase subunit KorB OS=Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 ...	223.0	[0..8]	[271..6]

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Predicted Domain #1

Region A:
Residues: [1-274]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASRLVEEYF RKETLPNIWC PGCSNGIVTM AIVRAIDNLK IDKDKVVVVS GIGCSSRASG  60
   61 YLDFNTLHTT HGRAIAFATG VKFANPELTV IVITGDGDNA AIGGNHFIHA ARRNIDITVV 120
  121 MYNNHIYGMT GGQASPTIPR YDKATTAPYG SIDRDFDICK LAIGAGATYV ARGTAYHVQQ 180
  181 LVKLIEKGIS HKGFSFIEAM SICPTYYGRR NKKGSPADML KWLKDNSIDI NKAAKMKPEE 240
  241 LEGKIIIGEF VNIEAPEYTE EYQKMVERLK VSVK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	28.39794
Match:	1ni4A
Description:	E1-beta subunit of pyruvate dehydrogenase (PP module)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	2.62581591393304	bayes_pls_golite062009
oxidoreductase activity	1.76278237247276	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors	1.33446932713773	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: