YRC Public Data Repository - Protein Structure Prediction

Protein:	PYRH_FUSNN
Organism:	Fusobacterium nucleatum subsp. nucleatum ATCC 25586
Length:	239 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for PYRH_FUSNN.

Description	E-value	Query Range	Subject Range
PYRH_CARHZ - Uridylate kinase OS=Carboxydothermus hydrogenoformans (strain ATCC BAA-161 / DSM 6008 / Z-2901) GN=p...	226.0	[0..1]	[239..1]
PYRH_LACJO - Uridylate kinase OS=Lactobacillus johnsonii GN=pyrH PE=3 SV=1 PYRH_LACJO - Uridylate kinase OS=Lactobacillus johnsonii (strain CNCM I-12250 / La1 / NCC 533) GN=pyrH PE=3 SV=1 gi\|227890235, gi... - gi\|227890235\|ref\|ZP_04008040.1\| uridylate kinase [Lactobacillus johnsonii ATCC 33200], gi\|227849237\|...	224.0	[0..1]	[239..1]
gi\|23002919 - gi\|23002919\|ref\|ZP_00046591.1\| COG0528: Uridylate kinase [Lactobacillus gasseri] gi\|227094235, gi... - gi\|227521138\|ref\|ZP_03951187.1\| uridylate kinase [Lactobacillus gasseri JV-V03], gi\|227094235\|gb\|EEI... gi\|238834756, gi... - gi\|238852610\|ref\|ZP_04643020.1\| UMP kinase [Lactobacillus gasseri 202-4], gi\|238834756\|gb\|EEQ26983.1... PYRH_LACGA - Uridylate kinase OS=Lactobacillus gasseri (strain ATCC 33323 / DSM 20243 / JCM 1131 / NCIMB 11718 / ...	224.0	[0..1]	[239..1]
gi\|15292789, gi\|... - gi\|9293891\|dbj\|BAB01794.1\| unnamed protein product [Arabidopsis thaliana], gi\|20258857\|gb\|AAM14100.1...	223.0	[0..4]	[236..94]
gi\|34762370, gi\|... - gi\|34762370\|ref\|ZP_00143372.1\| Uridylate kinase [Fusobacterium nucleatum subsp. vincentii ATCC 49256...	223.0	[0..1]	[239..1]
gi\|90437851, gi\|... - gi\|90580973\|ref\|ZP_01236774.1\| uridylate kinase [Vibrio angustum S14], gi\|90437851\|gb\|EAS63041.1\| ur...	222.0	[0..3]	[238..6]
gi\|89048834, gi\|... - gi\|89075418\|ref\|ZP_01161835.1\| uridylate kinase [Photobacterium sp. SKA34], gi\|89048834\|gb\|EAR54404.... gi\|88813751, gi\|... - gi\|88813751\|ref\|ZP_01128969.1\| uridylate kinase [Nitrococcus mobilis Nb-231], gi\|88788995\|gb\|EAR2014...	222.0	[0..3]	[237..6]
PYRH_PSEA6 - Uridylate kinase OS=Pseudoalteromonas atlantica (strain T6c / ATCC BAA-1087) GN=pyrH PE=3 SV=1	222.0	[0..3]	[238..6]
PYRH_COLP3 - Uridylate kinase OS=Colwellia psychrerythraea (strain 34H / ATCC BAA-681) GN=pyrH PE=3 SV=1	221.0	[0..3]	[238..6]
gi\|238714199, gi... - gi\|77957691\|ref\|ZP_00821740.1\| COG0528: Uridylate kinase [Yersinia bercovieri ATCC 43970], gi\|238784... gi\|238727861, gi... - gi\|77977746\|ref\|ZP_00833187.1\| COG0528: Uridylate kinase [Yersinia intermedia ATCC 29909], gi\|238792...	220.0	[0..3]	[239..6]

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Predicted Domain #1

Region A:
Residues: [1-239]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MESPFYKKIL LKLSGEALMG DQEFGISSDV IASYAKQIKE IVDLGVEVSI VIGGGNIFRG  60
   61 LSGAAQGVDR VTGDHMGMLA TVINSLALQN SIEKLGVPTR VQTAIEMPKV AEPFIKRRAQ 120
  121 RHLEKGRVVI FGAGTGNPYF TTDTAAALRA IEMETDVVIK ATKVDGIYDK DPVKYPDAKK 180
  181 YQTVTYNEVL AKDLKVMDAT AISLCRENKL PIIVFNSLDE GNLKKVVMGE HIGTTVVAD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	56.221849
Match:	2bneA
Description:	The structure of E. coli UMP kinase in complex with UMP
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
kinase activity	5.43826659128409	bayes_pls_golite062009
nucleobase, nucleoside, nucleotide kinase activity	4.76215533422168	bayes_pls_golite062009
nucleotide kinase activity	4.36245911991838	bayes_pls_golite062009
phosphotransferase activity, phosphate group as acceptor	4.17538459617947	bayes_pls_golite062009
uridylate kinase activity	3.54453921304057	bayes_pls_golite062009
catalytic activity	3.20382750184555	bayes_pls_golite062009
transferase activity	2.54481238004476	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	1.89315414622708	bayes_pls_golite062009
phosphotransferase activity, carboxyl group as acceptor	1.02979719559565	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: