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View Structure Prediction Details

Protein: gi|42519186, gi|...
Organism: Lactobacillus johnsonii NCC 533
Length: 730 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|42519186, gi|....

Description E-value Query
Range
Subject
Range
gi|58337744, gi|... - gi|58337744|ref|YP_194329.1| PTS enzyme IIABC [Lactobacillus acidophilus NCFM], gi|58255061|gb|AAV43...
gi|227904393, gi... - gi|227904393|ref|ZP_04022198.1| protein-N(pi)-phosphohistidine--sugar phosphotransferase [Lactobacil...
524.0 [0..3] [727..2]
gi|52144365, gi|... - gi|52144365|ref|YP_082463.1| PTS system, beta-glucoside-specific enzyme II, ABC component [Bacillus ...
440.0 [0..99] [718..1]
gi|15894686, gi|... - gi|15894686|ref|NP_348035.1| PTS system, beta-glucosides-specific IIABC component [Clostridium aceto...
gi|25287894 - pir||D97073 PTS system, beta-glucosides-specific IIABC component [imported] - Clostridium acetobutyl...
434.0 [0..99] [715..1]
gi|226902786, gi... - gi|237703522|ref|ZP_04534003.1| beta-glucoside-specific PTS system components IIABC [Escherichia sp....
gi|91074819, gi|... - gi|91213245|ref|YP_543231.1| beta-glucoside-specific PTS system components IIABC [Escherichia coli U...
432.0 [0..93] [715..18]
gi|26110892, gi|... - gi|26250462|ref|NP_756502.1| beta-glucoside-specific PTS system components IIABC [Escherichia coli C...
432.0 [0..93] [715..18]
PTV3B_BACHD - PTS system beta-glucoside-specific EIIBCA component OS=Bacillus halodurans (strain ATCC BAA-125 / DS...
PTV3B_BACHD, PTB... - PTS system beta-glucoside-specific EIIBCA component OS=Bacillus halodurans GN=bglP PE=3 SV=1, (Q9KF9...
431.0 [0..99] [716..1]
gi|49611326, gi|... - gi|50120800|ref|YP_049967.1| beta-glucoside-specific PTS system components IIABC [Pectobacterium atr...
431.0 [0..99] [715..1]
gi|75210668, gi|... - gi|75210668|ref|ZP_00710809.1| COG1263: Phosphotransferase system IIC components, glucose/maltose/N-...
429.0 [0..101] [715..1]
gi|45181608 - gi|45181608|gb|AAS55458.1| BglP [Pectobacterium carotovorum subsp. carotovorum]
429.0 [0..99] [715..1]

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Predicted Domain #1
Region A:
Residues: [1-86]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNNSYKEVAE KILVAVGGAE NINEVFNCIS RLRFYLKDSK KVNYPKLKLI PAISESEFED  60
   61 GQLQILLGQD VELYYDALVH LLKQKN

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 17.221849
Match: 1o2fB
Description: Glucose permease domain IIB
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.61117010765727 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [87-177]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ISGGEKKMSK VDEKDKKLAE EIVKLVGGKD NVISLVHCAT RLRFKLKDES KADDNAIKQL  60
   61 KGVMGVAHAG GQYQVIIGNN VADVYDQVIP L

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.522879
Match: 2r48A
Description: No description for 2r48A was found.

Predicted functions:

Term Confidence Notes
protein-N(PI)-phosphohistidine-sugar phosphotransferase activity 5.08041453921791 bayes_pls_golite062009
carbohydrate transmembrane transporter activity 4.49138214292642 bayes_pls_golite062009
glucoside transmembrane transporter activity 1.83892097143526 bayes_pls_golite062009
sugar transmembrane transporter activity 1.77053981674308 bayes_pls_golite062009
transporter activity 1.6837050020547 bayes_pls_golite062009
transmembrane transporter activity 1.5685227361887 bayes_pls_golite062009
substrate-specific transporter activity 1.32293422112884 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 1.217268678967 bayes_pls_golite062009
active transmembrane transporter activity 1.12964417923438 bayes_pls_golite062009
monosaccharide transmembrane transporter activity 0.71593290802554 bayes_pls_golite062009
beta-glucoside transmembrane transporter activity 0.50967675887857 bayes_pls_golite062009
binding 0.472595683811139 bayes_pls_golite062009
phosphotransferase activity, alcohol group as acceptor 0.37663629577414 bayes_pls_golite062009
fructose transmembrane transporter activity 0.225562559709031 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 0.0296784994545702 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [178-354]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LGLSQDHKEN TNKDKNIVNR FIKLLTTIFT PFLGVLAAAG VLKGFLTLLV VLHVLNTKSG  60
   61 TYLILYAAGD ALFYFLPVMI GFSTARTFKI NEYVGAIIGA ALCYPSLVQA YQMKQSIQFF 120
  121 NIPVILMNYT QTLIPAIIAV WLASILYKFL NNYLPSSLKL IFTPLITLMI AVPLTFL

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [355-440]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VVGPATSWAS EELTYSILWI YAHARVVAGF ILAGIWQAVV LLGLHWAFIP IFLNNIATRG  60
   61 FDPIDAMLYC TVFGQTGAAL ALVLKA

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [441-554]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KDSKFKEIGW PAVISGFLGV TEPIIYGVTL PHKKSFILGS IGSAFGGAIA AFSNAKMFGG  60
   61 FASGGIFGIP MFIDQKAGIN GSFMGFCLSL LVAFGIAFIS TLIWGDKIVS TTSK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #6
Region A:
Residues: [555-730]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KDFKVKRVEF KDQGIASPVQ GTALELKNVD DPVFSAGTIG KGIAVQPNND EIHAPFDGEV  60
   61 VSVFPTKHAI GLKSDNGVEL LIHLGINTVN LKGKYFEVKV EVGQKVKQGD LLETFDVDKI 120
  121 KAAGYDTVVP IIVTNANNFD DIIIEKKNGD SVRFEDQILM ATVDQEVEIP DNATQA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 40.69897
Match: 1ggrA
Description: Glucose-specific factor III (glsIII)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein-N(PI)-phosphohistidine-sugar phosphotransferase activity 3.63095060058431 bayes_pls_golite062009
carbohydrate transmembrane transporter activity 2.68179471492286 bayes_pls_golite062009
binding 0.587569240975485 bayes_pls_golite062009
transporter activity 0.416424316903358 bayes_pls_golite062009
transmembrane transporter activity 0.245554686788991 bayes_pls_golite062009
active transmembrane transporter activity 0.00716122418063003 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle