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View Structure Prediction Details

Protein: mec-2
Organism: Caenorhabditis elegans
Length: 317 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for mec-2.

Description E-value Query
Range
Subject
Range
gi|78512040, gi|... - gi|78688659|ref|ZP_00853327.1| HflK [Shewanella sp. MR-7], gi|78512040|gb|EAP25394.1| HflK [Shewanel...
250.0 [0..7] [316..2]

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Predicted Domain #1
Region A:
Residues: [1-98]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKPRETVATT SGTDSTPKTT ILPAKKDYFH VEANIQNEFG VCGWILTILS YLLIFFTLPI  60
   61 SACMCIKVVQ EYERAVIFRL GRLMPGGAKG PGIFFIVP

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [99-250]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 CIDTYRKVDL RVLSFEVPPQ EILSKDSVTV AVDAVVYFRI SNATISVTNV EDAARSTKLL  60
   61 AQTTLRNILG TKTLAEMLSD REAISHQMQT TLDEATEPWG VKVERVEVKD VRLPVQLQRA 120
  121 MAAEAEAARE ARAKVIVAEG EQKASRALKE AA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.045757
Match: 1winA
Description: Solution Structure of the Band 7 Domain of the mouse Flotillin 2 Protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 1.67282155252301 bayes_pls_golite062009
structural molecule activity 0.834496144484266 bayes_pls_golite062009
protein binding 0.769979871341236 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [251-317]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 EVIAESPSAL QLRYLQTLNS ISAEKNSTII FPFPIDLLSA FLQRTPPKVD NNFAFPTHKA  60
   61 GGIPSSS

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.


YRC Informatics Platform - Version 3.0
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