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View Structure Prediction Details

Protein: acr-15
Organism: Caenorhabditis elegans
Length: 479 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for acr-15.

Description E-value Query
Range
Subject
Range
ACHA6_MOUSE - Neuronal acetylcholine receptor subunit alpha-6 OS=Mus musculus GN=Chrna6 PE=2 SV=2
410.0 [0..2] [475..14]

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Predicted Domain #1
Region A:
Residues: [1-384]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MLLPILLHFL LLITQLNGSP AEVRLINDLM SGYVREERPT LDSSKPVVVS LGVFLQQIIN  60
   61 LSEKEEQLEV NAWLKFQWRD ENLRWEPTAY ENVTDLRHPP DALWTPDILL YNSVDSEFDS 120
  121 SYKVNLVNYH TGNINWMPPG IFKVSCKLDI YWFPFDEQVC YFKFGSWTYT RDKIQLEKGD 180
  181 FDFSEFIPNG EWIIIDYRTN ITVKQYECCP EQYEDITFTL HLRRRTLYYS FNLIAPVLLT 240
  241 MILVILGFTV SPETCEKVGL QISVSLAICI FLTIMSELTP QTSEAVPLLG VFFHTCNFIS 300
  301 VLATSFTVYV QSFHFRNQHV HERMDFWMRF ILLEWSPWLL RMKMPDRENN FQTLTESWKG 360
  361 RNRRESMART AFEYADGPVT QIHS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 70.221849
Match: 2bg9C
Description: Refined structure of the nicotinic acetylcholine receptor at 4A resolution.
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [385-479]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGIMLKDNFE ELIYQVKQEK IADEKGIERL RVLQKIYDHV KMIREHDDDN DEDSRVALEW  60
   61 RFAAIVVDRL CLLAFSLLIV VVSIIIALRA PYLFA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 43.522879
Match: 1oedB
Description: Acetylcholine receptor protein, beta chain
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle