YRC Public Data Repository - Protein Structure Prediction

Protein:	EMC4_YEAST
Organism:	Saccharomyces cerevisiae S288c
Length:	190 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EMC4_YEAST.

Description	E-value	Query Range	Subject Range
gi\|151943587 - gi\|151943587\|gb\|EDN61897.1\| conserved protein [Saccharomyces cerevisiae YJM789] EMC4_YEAST - ER membrane protein complex subunit 4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=EM... EMC4 - Member of a transmembrane complex required for efficient folding of proteins in the ER; null mutant ... gi\|190407165 - gi\|190407165\|gb\|EDV10432.1\| conserved hypothetical protein [Saccharomyces cerevisiae RM11-1a] gi\|207345553 - gi\|207345553\|gb\|EDZ72333.1\| YGL231Cp-like protein [Saccharomyces cerevisiae AWRI1631]	4.0E-73	[1..190]	[1..190]
CE26347 - status:Confirmed UniProt:Q9N4N3 protein_id:AAF60946.1	6.0E-51	[14..173]	[8..155]
YQ13_SCHPO - ER membrane protein complex subunit 4 OS=Schizosaccharomyces pombe (strain 972 / ATCC 24843) GN=SPCC... SPCC1281.03c - DUF1077 family protein	5.0E-50	[24..176]	[25..176]
CG11137-PA - This gene is referred to in FlyBase by the symbol Dmel\CG11137 (CG11137, FBgn0037199). It is a prote... gi\|220959180, gi... - gi\|220959180\|gb\|ACL92133.1\| CG11137-PA [synthetic construct], gi\|220950118\|gb\|ACL87602.1\| CG11137-PA...	5.0E-50	[17..187]	[11..165]
gi\|12834476 - gi\|12834476\|dbj\|BAB22926.1\| unnamed protein product [Mus musculus]	7.0E-49	[57..185]	[55..181]
gi\|90077506 - gi\|90077506\|dbj\|BAE88433.1\| unnamed protein product [Macaca fascicularis] TMEM85 - transmembrane protein 85 TMM85_PONPY - Transmembrane protein 85 - Pongo pygmaeus (Orangutan) gi\|109080509 - gi\|109080509\|ref\|XP_001087244.1\| PREDICTED: similar to CG11137-PA isoform 2 [Macaca mulatta] EMC4_PONAB - ER membrane protein complex subunit 4 OS=Pongo abelii GN=EMC4 PE=2 SV=1 ENSCJAT00000041516 - null	9.0E-49	[57..185]	[55..181]
gi\|16226450, gi\|... - gi\|18416375\|ref\|NP_568238.1\| unknown protein [Arabidopsis thaliana], gi\|16323254\|gb\|AAL15361.1\| AT5g...	2.0E-47	[17..187]	[17..179]

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Predicted Domain #1

Region A:
Residues: [1-190]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEQEPYEWA KHLLDTKYIE KYNIQNSNTL PSPPGFEGNS SKGNVTRKQQ DATSQTTSLA  60
   61 QKNQITVLQV QKAWQIALQP AKSIPMNIFM SYMSGTSLQI IPIMTALMLL SGPIKAIFST 120
  121 RSAFKPVLGN KATQSQVQTA MFMYIVFQGV LMYIGYRKLN SMGLIPNAKG DWLPWERIAH 180
  181 YNNGLQWFSD

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits