YRC Public Data Repository - Protein Structure Prediction

Protein:	ERV1_YEAST
Organism:	Saccharomyces cerevisiae S288c
Length:	189 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ERV1_YEAST.

Description	E-value	Query Range	Subject Range
GFER - growth factor, augmenter of liver regeneration	229.0	[0..8]	[189..57]
gi\|109127227 - gi\|109127227\|ref\|XP_001082639.1\| PREDICTED: similar to erv1-like growth factor isoform 2 [Macaca mul...	221.0	[0..8]	[189..57]
gi\|73959530 - gi\|73959530\|ref\|XP_537010.2\| PREDICTED: similar to erv1-like growth factor [Canis familiaris]	215.0	[0..12]	[189..166]
ALR_MOUSE - FAD-linked sulfhydryl oxidase ALR OS=Mus musculus GN=Gfer PE=1 SV=2	212.0	[0..28]	[189..62]
erv1 - sulfhydryl oxidase ERV1_SCHPO - Mitochondrial FAD-linked sulfhydryl oxidase erv1 OS=Schizosaccharomyces pombe (strain 972 / ATCC 248...	208.0	[0..21]	[182..14]
gi\|49525710 - gi\|49525710\|emb\|CAG59329.1\| unnamed protein product [Candida glabrata] gi\|50287947, gi\|... - gi\|50287947\|ref\|XP_446402.1\| unnamed protein product [Candida glabrata], gi\|49525710\|emb\|CAG59329.1\|...	206.0	[0..12]	[189..3]

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Predicted Domain #1

Region A:
Residues: [1-72]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKAIDKMTDN PPQEGLSGRK IIYDEDGKPC RSCNTLLDFQ YVTGKISNGL KNLSSNGKLA  60
   61 GTGALTGEAS EL

[Run NCBI BLAST on this sequence.]

Detection Method:

MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

		MCM Score	GO Score	GO Term	SCOP Match	SCOP Description
View	Download	0.497	N/A	N/A	a.4.5	"Winged helix" DNA-binding domain
View	Download	0.460	N/A	N/A	a.4.5	"Winged helix" DNA-binding domain
View	Download	0.460	N/A	N/A	a.4.5	"Winged helix" DNA-binding domain
View	Download	0.431	N/A	N/A	a.4.5	"Winged helix" DNA-binding domain
View	Download	0.348	N/A	N/A	d.348.1	Description not found.
View	Download	0.342	N/A	N/A	a.4.5	"Winged helix" DNA-binding domain
View	Download	0.339	N/A	N/A	d.76.1	GYF domain
View	Download	0.289	N/A	N/A	d.58.11	EF-G/eEF-2 domains III and V
View	Download	0.249	N/A	N/A	a.144.2	Ribosomal protein L20
View	Download	0.238	N/A	N/A	g.41.10	Zn-finger domain of Sec23/24

Predicted Domain #2

Region A:
Residues: [73-189]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPGSRTYRKV DPPDVEQLGR SSWTLLHSVA ASYPAQPTDQ QKGEMKQFLN IFSHIYPCNW  60
   61 CAKDFEKYIR ENAPQVESRE ELGRWMCEAH NKVNKKLRKP KFDCNFWEKR WKDGWDE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	45.39794
Match:	1oqcA
Description:	Augmenter of liver regeneration
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits