YRC Public Data Repository - Protein Structure Prediction

Protein:	EG10849
Organism:	Escherichia coli str. K-12 substr. MG1655
Length:	1426 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EG10849.

Description	E-value	Query Range	Subject Range
gi\|194437406, gi... - gi\|83587048\|ref\|ZP_00925678.1\| COG3209: Rhs family protein [Escherichia coli 101-1], gi\|194437406\|re...	1053.0	[0..1]	[1426..1]
gi\|157079857, gi... - gi\|75189565\|ref\|ZP_00702832.1\| COG3209: Rhs family protein [Escherichia coli E24377A], gi\|157157827\|...	1044.0	[0..1]	[1426..1]
gi\|188490910, gi... - gi\|75514620\|ref\|ZP_00736875.1\| COG3209: Rhs family protein [Escherichia coli 53638], gi\|188495711\|re...	1040.0	[0..1]	[1426..1]
gi\|170082996, gi... - gi\|170082996\|ref\|YP_001732316.1\| rhsB element core protein RshB [Escherichia coli str. K-12 substr. ... gi\|89110530, gi\|... - gi\|89110530\|ref\|AP_004310.1\| rhsB element core protein RshB [Escherichia coli str. K-12 substr. W311... EG10847 - Rhs protein with DUF4329 family putative toxin domain; putative neighboring cell growth inhibitor / ... gi\|238902573, gi... - gi\|238902573\|ref\|YP_002928369.1\| rhsB element core protein RshB [Escherichia coli BW2952], gi\|238863... RHSB_ECOLI - Protein rhsB precursor - Escherichia coli EG10847 - Rhs protein with DUF4329 family putative toxin domain; putative neighboring cell growth inhibitor / ...	1012.0	[0..1]	[1420..1]
gi\|194414428, gi... - gi\|75211350\|ref\|ZP_00711449.1\| COG3209: Rhs family protein [Escherichia coli B171], gi\|194427388\|ref...	1009.0	[0..1]	[1420..1]
gi\|157068639, gi... - gi\|75197408\|ref\|ZP_00707478.1\| COG3209: Rhs family protein [Escherichia coli HS], gi\|157162959\|ref\|Y...	1008.0	[0..1]	[1420..1]
gi\|567056 - gi\|567056\|gb\|AAA56755.1\| Rhs core protein with extension	1003.0	[0..1]	[1420..1]
gi\|75231664, gi\|... - gi\|75231664\|ref\|ZP_00718022.1\| COG3209: Rhs family protein [Escherichia coli B7A], gi\|191165280\|ref\|...	1001.0	[0..1]	[1420..1]
gi\|13364340, gi\|... - gi\|15834118\|ref\|NP_312891.1\| RhsH [Escherichia coli O157:H7], gi\|13364340\|dbj\|BAB38287.1\| RhsH core ... gi\|254597737, gi... - gi\|254597756\|gb\|ACT76101.1\| RhsF [Escherichia coli], gi\|254597741\|gb\|ACT76094.1\| RhsF [Escherichia c... gi\|13364340, gi\|... - gi\|15834118\|ref\|NP_312891.1\| RhsH [Escherichia coli O157:H7 str. Sakai], gi\|13364340\|dbj\|BAB38287.1\|... gi\|217326140, gi... - gi\|217326140\|ref\|ZP_03442224.1\| RHS Repeat family protein [Escherichia coli O157:H7 str. TW14588], g... gi\|168761677, gi... - gi\|189367895\|gb\|EDU86311.1\| protein RhsA [Escherichia coli O157:H7 str. EC4501], gi\|168761677\|ref\|ZP...	965.0	[0..1]	[1414..1]

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Predicted Domain #1

Region A:
Residues: [1-322]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGKPAARQG DMTQYGGPIV QGSAGVRIGA PTGVACSVCP GGMTSGNPVN PLLGAKVLPG  60
   61 ETDLALPGPL PFILSRTYSS YRTKTPAPVG VFGPGWKAPS DIRLQLRDDG LILNDNGGRS 120
  121 IHFEPLLPGE AVYSRSESMW LVRGGKAAQP DGHTLARLWG ALPPDIRLSP HLYLATNSAQ 180
  181 GPWWILGWSE RVPGAEDVLP APLPPYRVLT GMADRFGRTL TYRREAAGDL AGEITGVTDG 240
  241 AGREFRLVLT TQAQRAEEAR TSSLSSSDSS RPLSASAFPD TLPGTEYGPD RGIRLSAVWL 300
  301 MHDPAYPESL PAAPLVRYTY TE

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	2.7
Match:	2fkgA
Description:	No description for 2fkgA was found.

Predicted Domain #2

Region A:
Residues: [323-430]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AGELLAVYDR SNTQVRAFTY DAQHPGRMVA HRYAGRPEMR YRYDDTGRVV EQLNPAGLSY  60
   61 RYLYEQDRIT VTDSLNRREV LHTEGGAGLK RVVKKELADG SVTRSGYD

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	11.69897
Match:	2pm6B
Description:	No description for 2pm6B was found.

Predicted Domain #3

Region A:
Residues: [431-927]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 AAGRLTAQTD AAGRRTEYGL NVVSGDITDI TTPDGRETKF YYNDGNQLTA VVSPDGLESR  60
   61 REYDEPGRLV SETSRSGETV RYRYDDAHSE LPATTTDATG STRQMTWSRY GQLLAFTDCS 120
  121 GYQTRYEYDR FGQMTAVHRE EGISLYRRYD NRGRLTSVKD AQGRETRYEY NAAGDLTAVI 180
  181 TPDGNRSETQ YDAWGKAVST TQGGLTRSME YDAAGRVISL TNENGSHSVF SYDALDRLVQ 240
  241 QGGFDGRTQR YHYDLTGKLT QSEDEGLVIL WYYDESDRIT HRTVNGEPAE QWQYDGHGWL 300
  301 TDISHLSEGH RVAVHYGYDD KGRLTGECQT VENPETGELL WQHETKHAYN EQGLANRVTP 360
  361 DSLPPVEWLT YGSGYLAGMK LGGTPLVEYT RDRLHRETVR SFGSMAGSNA AYELTSTYTP 420
  421 AGQLQSQHLN SLVYDRDYGW SDNGDLVRIS GPRQTREYGY SATGRLESVR TLAPDLDIRI 480
  481 PYATDPAGNR LPDPELH

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	17.30103
Match:	1nr0A
Description:	Actin interacting protein 1
Matching Structure (courtesy of the PDB):

Predicted Domain #4

Region A:
Residues: [928-1266]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 PDSTLTVWPD NRIAEDAHYV YRHDEYGRLT EKTDRIPAGV IRTDDERTHH YHYDSQHRLV  60
   61 FYTRIQHGEP LVESRYLYDP LGRRMAKRVW RRERDLTGWM SLSRKPEVTW YGWDGDRLTT 120
  121 VQTDTTRIQT VYEPGSFTPL IRVETENGER EKAQRRSLAE TLQQEGSENG HGVVFPAELV 180
  181 RLLDRLEEEI RADRVSSESR AWLAQCGLTV EQLARQVEPE YTPARKAHLY HCDHRGLPLA 240
  241 LISEDGNTAW SAEYDEWGNQ LNEENPHHVY QPYRLPGQQH DEESGLYYNR HRYYDPLQGR 300
  301 YITQDPMGLK GGWNLYQYPL NPLQQIDPMG LLQTWDDAR

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	2.65
Match:	2fkgA
Description:	No description for 2fkgA was found.

Predicted Domain #5

Region A:
Residues: [1267-1426]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SGACTGGVCG VLSRIIGPSK FDSTADAALD ALKETQNRSL CNDMEYSGIV CKDTNGKYFA  60
   61 SKAETDNLRK ESYPLKRKCP TGTDRVAAYH THGADSHGDY VDEFFSSSDK NLVRSKDNNL 120
  121 EAFYLATPDG RFEALNNKGE YIFIRNSVPG LSSVCIPYHD

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits