YRC Public Data Repository - Protein Structure Prediction

Protein:	EG12423
Organism:	Escherichia coli str. K-12 substr. MG1655
Length:	283 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for EG12423.

Description	E-value	Query Range	Subject Range
gi\|157156427, gi... - gi\|75189438\|ref\|ZP_00702705.1\| COG2175: Probable taurine catabolism dioxygenase [Escherichia coli E2...	305.0	[0..1]	[283..1]
gi\|74310938, gi\|... - gi\|74310938\|ref\|YP_309357.1\| taurine dioxygenase [Shigella sonnei Ss046], gi\|73854415\|gb\|AAZ87122.1\|...	305.0	[0..1]	[283..1]
gi\|189373761, gi... - gi\|189373761\|gb\|EDU92177.1\| taurine dioxygenase [Escherichia coli O157:H7 str. EC869], gi\|168786201\|... gi\|188999387, gi... - gi\|188999387\|gb\|EDU68373.1\| taurine dioxygenase [Escherichia coli O157:H7 str. EC4076], gi\|168783221... gi\|169756183, gi... - gi\|170021255\|ref\|YP_001726209.1\| taurine dioxygenase [Escherichia coli ATCC 8739], gi\|169756183\|gb\|A... gi\|168800238, gi... - gi\|189377380\|gb\|EDU95796.1\| taurine dioxygenase [Escherichia coli O157:H7 str. EC508], gi\|168800238\|... gi\|208726398, gi... - gi\|208806597\|ref\|ZP_03248934.1\| taurine dioxygenase [Escherichia coli O157:H7 str. EC4206], gi\|20872... gi\|13359879, gi\|... - gi\|15829676\|ref\|NP_308449.1\| taurine dioxygenase [Escherichia coli O157:H7 str. Sakai], gi\|13359879\|... gi\|195938569 - gi\|195938569\|ref\|ZP_03083951.1\| taurine dioxygenase [Escherichia coli O157:H7 str. EC4024] gi\|124528915, gi... - gi\|124528915\|ref\|ZP_01700100.1\| Taurine dioxygenase [Escherichia coli B], gi\|124500252\|gb\|EAY47728.1... gi\|208822961, gi... - gi\|208822961\|ref\|ZP_03263279.1\| taurine dioxygenase [Escherichia coli O157:H7 str. EC4042], gi\|20873... gi\|208815909, gi... - gi\|208815909\|ref\|ZP_03257088.1\| taurine dioxygenase [Escherichia coli O157:H7 str. EC4045], gi\|20873... gi\|188015925, gi... - gi\|188015925\|gb\|EDU54047.1\| taurine dioxygenase [Escherichia coli O157:H7 str. EC4113], gi\|168749818... gi\|189368052, gi... - gi\|189368052\|gb\|EDU86468.1\| taurine dioxygenase [Escherichia coli O157:H7 str. EC4501], gi\|168761560... gi\|168756897, gi... - gi\|189355960\|gb\|EDU74379.1\| taurine dioxygenase [Escherichia coli O157:H7 str. EC4401], gi\|168756897... gi\|168776339, gi... - gi\|187768267\|gb\|EDU32111.1\| taurine dioxygenase [Escherichia coli O157:H7 str. EC4196], gi\|168776339... gi\|189362420, gi... - gi\|189362420\|gb\|EDU80839.1\| taurine dioxygenase [Escherichia coli O157:H7 str. EC4486], gi\|168768306... gi\|209744492, gi... - pir\|\|B85532 taurine dioxygenase, 2-oxoglutarate-dependent [imported] - Escherichia coli (strain O157... gi\|15800098, gi\|... - gi\|15800098\|ref\|NP_286110.1\| taurine dioxygenase [Escherichia coli O157:H7 EDL933], gi\|12513209\|gb\|A... gi\|13359879, gi\|... - gi\|15829676\|ref\|NP_308449.1\| taurine dioxygenase [Escherichia coli O157:H7], gi\|13359879\|dbj\|BAB3384... gi\|217325762, gi... - gi\|217325762\|ref\|ZP_03441846.1\| taurine dioxygenase [Escherichia coli O157:H7 str. TW14588], gi\|2173... gi\|209160608, gi... - gi\|209399208\|ref\|YP_002269009.1\| taurine dioxygenase [Escherichia coli O157:H7 str. EC4115], gi\|2091... tr\|A0A0X8UG71\|A0... - Taurine dioxygenase OS=Escherichia coli (strain K12) GN=tauD PE=4 SV=1 gi\|242376150, gi... - gi\|251783877\|ref\|YP_002998181.1\| hypothetical protein B21_00322 [Escherichia coli BL21], gi\|24237615... gi\|194422154, gi... - gi\|83585708\|ref\|ZP_00924350.1\| COG2175: Probable taurine catabolism dioxygenase [Escherichia coli 10... gi\|253774647, gi... - gi\|254287240\|ref\|YP_003052988.1\| taurine dioxygenase [Escherichia coli BL21(DE3)], gi\|253976547\|gb\|A... gi\|254160437, gi... - gi\|254160437\|ref\|YP_003043545.1\| taurine dioxygenase [Escherichia coli B str. REL606], gi\|253972338\|... gi\|254590948, gi... - gi\|254791548\|ref\|YP_003076385.1\| taurine dioxygenase, 2-oxoglutarate-dependent [Escherichia coli O15...	305.0	[0..1]	[283..1]
gi\|209917581, gi... - gi\|209917581\|ref\|YP_002291665.1\| taurine dioxygenase [Escherichia coli SE11], gi\|209910840\|dbj\|BAG75... gi\|218359699, gi... - gi\|218552931\|ref\|YP_002385844.1\| taurine dioxygenase [Escherichia coli IAI1], gi\|218359699\|emb\|CAQ97... gi\|193065162, gi... - gi\|75256745\|ref\|ZP_00728350.1\| COG2175: Probable taurine catabolism dioxygenase [Escherichia coli E2... gi\|190903240, gi... - gi\|75230098\|ref\|ZP_00716602.1\| COG2175: Probable taurine catabolism dioxygenase [Escherichia coli B7... gi\|194428826, gi... - gi\|75209929\|ref\|ZP_00710118.1\| COG2175: Probable taurine catabolism dioxygenase [Escherichia coli B1... gi\|157159884, gi... - gi\|75194589\|ref\|ZP_00704659.1\| COG2175: Probable taurine catabolism dioxygenase [Escherichia coli HS...	304.0	[0..1]	[283..1]
gi\|110342225, gi... - gi\|110640633\|ref\|YP_668361.1\| taurine dioxygenase [Escherichia coli 536], gi\|110342225\|gb\|ABG68462.1... gi\|191173476, gi... - gi\|75238700\|ref\|ZP_00722688.1\| COG2175: Probable taurine catabolism dioxygenase [Escherichia coli F1...	303.0	[0..1]	[283..1]
gi\|75237247, gi\|... - gi\|75237247\|ref\|ZP_00721294.1\| COG2175: Probable taurine catabolism dioxygenase [Escherichia coli E1...	303.0	[0..1]	[283..1]
gi\|237707642, gi... - gi\|237707642\|ref\|ZP_04538123.1\| taurine dioxygenase [Escherichia sp. 3_2_53FAA], gi\|226898852\|gb\|EEH... gi\|115511759, gi... - gi\|117622635\|ref\|YP_851548.1\| taurine dioxygenase [Escherichia coli APEC O1], gi\|115511759\|gb\|ABI998... gi\|91209433, gi\|... - gi\|91209433\|ref\|YP_539419.1\| taurine dioxygenase [Escherichia coli UTI89], gi\|91071007\|gb\|ABE05888.1... gi\|218557281, gi... - gi\|218557281\|ref\|YP_002390194.1\| taurine dioxygenase [Escherichia coli S88], gi\|218364050\|emb\|CAR017...	303.0	[0..1]	[283..1]
gi\|81244269, gi\|... - gi\|82542858\|ref\|YP_406805.1\| taurine dioxygenase [Shigella boydii Sb227], gi\|81244269\|gb\|ABB64977.1\|...	302.0	[0..1]	[283..1]
gi\|81239999, gi\|... - gi\|82775851\|ref\|YP_402198.1\| taurine dioxygenase [Shigella dysenteriae Sd197], gi\|81239999\|gb\|ABB607...	302.0	[0..1]	[283..1]
gi\|110804391, gi... - gi\|110804391\|ref\|YP_687911.1\| taurine dioxygenase [Shigella flexneri 5 str. 8401], gi\|110613939\|gb\|A... gi\|30061819, gi\|... - gi\|30061819\|ref\|NP_835990.1\| taurine dioxygenase [Shigella flexneri 2a str. 2457T], gi\|30040061\|gb\|A... gi\|24111694, gi\|... - gi\|24111694\|ref\|NP_706204.1\| taurine dioxygenase [Shigella flexneri 2a str. 301], gi\|24050471\|gb\|AAN...	301.0	[0..1]	[283..1]

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Predicted Domain #1

Region A:
Residues: [1-283]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSERLSITPL GPYIGAQISG ADLTRPLSDN QFEQLYHAVL RHQVVFLRDQ AITPQQQRAL  60
   61 AQRFGELHIH PVYPHAEGVD EIIVLDTHND NPPDNDNWHT DVTFIETPPA GAILAAKELP 120
  121 STGGDTLWTS GIAAYEALSV PFRQLLSGLR AEHDFRKSFP EYKYRKTEEE HQRWREAVAK 180
  181 NPPLLHPVVR THPVSGKQAL FVNEGFTTRI VDVSEKESEA LLSFLFAHIT KPEFQVRWRW 240
  241 QPNDIAIWDN RVTQHYANAD YLPQRRIMHR ATILGDKPFY RAG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	83.09691
Match:	1gqwA
Description:	Taurine/alpha-ketoglutarate dioxygenase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors	1.41007985416065	bayes_pls_golite062009
catalytic activity	1.29176034651701	bayes_pls_golite062009
oxidoreductase activity	0.95783232811757	bayes_pls_golite062009
taurine dioxygenase activity	0.594076608400231	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: