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View Structure Prediction Details

Protein: ORP2A_ARATH
Organism: Arabidopsis thaliana
Length: 721 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ORP2A_ARATH.

Description E-value Query
Range
Subject
Range
gi|42570131 - gi|42570131|ref|NP_849343.2| ORP1C (OSBP(OXYSTEROL BINDING PROTEIN)-RELATED PROTEIN 1C); oxysterol b...
511.0 [0..53] [716..106]
gi|57114406 - gi|57114406|gb|AAM97165.2| putative oxysterol binding protein [Oryza sativa (japonica cultivar-group...
506.0 [0..53] [717..89]
gi|78440948 - gi|78440948|gb|ABB43279.1| oxysterol-binding related protein 1 [Petunia integrifolia]
488.0 [0..53] [716..73]

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Predicted Domain #1
Region A:
Residues: [1-270]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRVKELHPLC CITLESPHGI NSQSPEEPVT TALTRSRSLP AKSLTGGSES ETVAGILYKW  60
   61 TNFGKGWRSR WFLLRNGILS YSKIRRPENL NLLSPDDDVR LIGDISGERL SRMDSCSGRR 120
  121 KQQKTVGIVH LKVSSFRESK SDDRKFYIFT ATKTLHLRTD SITDRAAWLQ ALASTKCIFP 180
  181 LRSLNGDFSF IPPKDLSIST ERLKKRLHEE GMNENLVKEC EQIMLSEFSE MHGQVKLLHE 240
  241 ERTNLLDALR QLEAANLEVG ASGKHEFSSL 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 11.39794
Match: 1eazA
Description: Tapp1
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [271-334]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GRGKYSECST TASSDGKQEF EDVSEEDEPS FHDTKEFFNE PNIGSESNLA ISGHTDIKRR  60
   61 TKLP

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [335-721]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DPAEKEKGVS LWSMIKDNVG KDLTRVCLPV YFNEPISSLQ KCFEDLEYSY LLDRAYEHGK  60
   61 SGNGLLRALN VAAFAVSGYA STEGRHCKPF NPLLGETYEA DFPEKGIRFF SEKVSHHPTV 120
  121 IACHCEGKGW KFWGDTNLRS KFWGRSIQVE PVGVLTLEFD DGEVFQWSKV TSTIYNIILG 180
  181 KLYCDHHGVM QIRGNRQYSC TLKFKEQSIL ERNPHQVNGF VEDVAGQKAA TIFGKWDDSL 240
  241 YYVAGDGINK SKVSDPASNA SLLWKRTKPP PNVTRYNLTS FAITLNELTP GLQEILPPTD 300
  301 SRLRPDQRHL ENGEYEKANL EKQRLERRQR MSRQLQESGW RPRWFERQGE SDTFKYTGGY 360
  361 WEARGHRNWD DCPDIFGEFT EELADAA

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 63.522879
Match: 1zhtA
Description: Structure of yeast oxysterol binding protein Osh4 in complex with 7-hydroxycholesterol
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle