YRC Public Data Repository - Protein Structure Prediction

Protein:	AP4A_PIG
Organism:	Sus scrofa
Length:	147 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for AP4A_PIG.

Description	E-value	Query Range	Subject Range
ADPP_METJA - ADP-ribose pyrophosphatase OS=Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / ... ADPP_METJA - ADP-ribose pyrophosphatase OS=Methanocaldococcus jannaschii GN=nudF PE=1 SV=1	116.0	[0..10]	[141..39]
gi\|71906713, gi\|... - gi\|71906713\|ref\|YP_284300.1\| NUDIX hydrolase [Dechloromonas aromatica RCB], gi\|71846334\|gb\|AAZ45830....	115.0	[0..1]	[140..118]
gi\|83949916, gi\|... - gi\|83949916\|ref\|ZP_00958649.1\| hydrolase, NUDIX family protein of the NudH subfamily [Roseovarius nu...	114.0	[0..1]	[145..1]
gi\|84393080, gi\|... - gi\|84393080\|ref\|ZP_00991846.1\| NADH pyrophosphatase [Vibrio splendidus 12B01], gi\|84376332\|gb\|EAP932...	114.0	[0..1]	[135..119]
gi\|13384960, gi\|... - ref\|NP_079815.1\| nudix (nucleoside diphosphate linked moiety X)-type motif 2 [Mus musculus], gi\|128...	114.0	[0..1]	[147..1]
gi\|77459459, gi\|... - gi\|77459459\|ref\|YP_348966.1\| NUDIX hydrolase [Pseudomonas fluorescens Pf0-1], gi\|77383462\|gb\|ABA7497...	113.0	[0..1]	[141..28]
RPPH_HAEI8 - RNA pyrophosphohydrolase OS=Haemophilus influenzae (strain 86-028NP) GN=rppH PE=3 SV=1	113.0	[0..11]	[144..7]
gi\|109111196 - gi\|109111196\|ref\|XP_001098004.1\| PREDICTED: nudix (nucleoside diphosphate linked moiety X)-type moti...	113.0	[0..1]	[147..1]
gi\|229813037, gi... - gi\|229844043\|ref\|ZP_04464184.1\| dinucleoside polyphosphate hydrolase [Haemophilus influenzae 6P18H1]... gi\|42631225 - gi\|42631225\|ref\|ZP_00156763.1\| COG0494: NTP pyrophosphohydrolases including oxidative damage repair ... gi\|145641911, gi... - gi\|145641911\|ref\|ZP_01797485.1\| dinucleoside polyphosphate hydrolase [Haemophilus influenzae R3021],... gi\|145641911 - gi\|145641911\|ref\|ZP_01797485.1\| dinucleoside polyphosphate hydrolase [Haemophilus influenzae R3021] gi\|145636968, gi... - gi\|145636968\|ref\|ZP_01792632.1\| dinucleoside polyphosphate hydrolase [Haemophilus influenzae PittHH]... gi\|145634069, gi... - gi\|145634069\|ref\|ZP_01789780.1\| dinucleoside polyphosphate hydrolase [Haemophilus influenzae PittAA]... gi\|145632279, gi... - gi\|145632279\|ref\|ZP_01788014.1\| dinucleoside polyphosphate hydrolase [Haemophilus influenzae 3655], ...	113.0	[0..11]	[144..7]

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Predicted Domain #1

Region A:
Residues: [1-147]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MALRACGLII FRRRLIPKVD NTAIEFLLLQ ASNGIHHWTP PKGHVEPGES DLQTALRETQ  60
   61 EEAGIDAGQL TIIEGFRKEL NYVAWEKPKT VIYWLAEVKD YDVEVRLSRE HQAYRWLGLD 120
  121 EACQLAQFKD MKAVLQEGHQ FLCSMAA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	25.0
Match:	1xsaA
Description:	Structure of the nudix enzyme AP4A hydrolase from homo sapiens (E63A mutant)
Matching Structure (courtesy of the PDB):

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits