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View Structure Prediction Details

Protein: gi|23613549, gi|...
Organism: Plasmodium falciparum 3D7
Length: 932 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|23613549, gi|....

Description E-value Query
Range
Subject
Range
gi|7494459, gi|1... - pir||T30840 serine-repeat antigen 2 precursor - Plasmodium vivax, gi|1381088|gb|AAB41485.1| V-SERA ...
751.0 [0..1] [932..1]
gi|16804969, gi|... - gi|3845160|gb|AAC71859.1| serine repeat antigen 3 (SERA-3) [Plasmodium falciparum 3D7], gi|16804969|...
gi|7494436 - pir||D71617 SERA antigen/papain-like proteinase with active Ser PFB0350c - malaria parasite (Plasmod...
734.0 [0..1] [932..1]
gi|83315603 - gi|83315603|ref|XP_730865.1| Papain family cysteine protease [Plasmodium yoelii yoelii str. 17XNL]
gi|23490720 - gi|23490720|gb|EAA22430.1| Papain family cysteine protease, putative [Plasmodium yoelii yoelii]
689.0 [0..23] [929..211]

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Predicted Domain #1
Region A:
Residues: [1-124]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKVSFTLFFI IYIILNCDVL KCEVESSDST SFLNLISGQS SSNSDDTVSS SDSRGVVASV  60
   61 SGTVDSDVSR TDSTGNVNSK NSELSETRQN SVEQNNNSNS SDNSIKIKSA FLKENVGVKI 120
  121 TGPC

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [125-203]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DEGFGLVMVP HIIINVDTRN TDIQLGKKSS EINYGIKLRK KGKDEYEEKV GIDLLKNVCE  60
   61 TGKNFKFVAY IKGDELIIK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

    MCM
Score
GO
Score
GO
Term
SCOP
Match
SCOP Description
View Download 0.455 N/A N/A b.114.1 N-utilization substance G protein NusG, insert domain
View Download 0.445 N/A N/A d.15.1 Ubiquitin-like
View Download 0.444 N/A N/A d.15.1 Ubiquitin-like
View Download 0.404 N/A N/A d.52.9 Description not found.
View Download 0.403 N/A N/A d.15.1 Ubiquitin-like
View Download 0.401 N/A N/A d.68.3 SirA-like
View Download 0.391 N/A N/A b.26.1 SMAD/FHA domain
View Download 0.391 N/A N/A d.170.2 A heparin-binding domain
View Download 0.391 N/A N/A d.15.1 Ubiquitin-like
View Download 0.365 N/A N/A d.15.2 CAD & PB1 domains
View Download 0.300 N/A N/A d.52.8 Description not found.
View Download 0.205 N/A N/A d.110.3 PYP-like sensor domain (PAS domain)

Predicted Domain #3
Region A:
Residues: [204-350]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 WKVIEEGNIP IDIKKFKIKR MSPPITSIQV FSSMSDEKSF VLENKNYVVT NNMPEKCEAL  60
   61 ATNCFLSGNI DIEKCYQCSL LVENDSKSDV CYNFISRENK EKLNEERFKV KGSTEYEESV 120
  121 ESELKGAIDL LISSFYKSDG ENGENVL

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

    MCM
Score
SCOP
Match
SCOP Description
View Download 0.477 a.78.1 Fatty acid responsive transcription factor FadR, C-terminal domain
View Download 0.471 a.78.1 Fatty acid responsive transcription factor FadR, C-terminal domain
View Download 0.445 c.56.1 HybD-like
View Download 0.415 f.1.4 Bcl-2 inhibitors of programmed cell death
View Download 0.411 c.36.1 Thiamin diphosphate-binding fold (THDP-binding)
View Download 0.372 a.25.1 Ferritin-like
View Download 0.361 d.129.3 Bet v1-like
View Download 0.322 b.82.3 cAMP-binding domain-like
View Download 0.303 a.26.1 4-helical cytokines
View Download 0.266 d.14.1 Ribosomal protein S5 domain 2-like
View Download 0.241 f.21.2 Fumarate reductase respiratory complex transmembrane subunits
View Download 0.234 d.17.4 NTF2-like

Predicted Domain #4
Region A:
Residues: [351-744]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 ISFEDLNSTL EDDIINFCSL LKLVDLSGTF MNHQIGTTAD AFNNIVKLLK EHKEEDEFVL  60
   61 RTKLRNPALC MKNVDDWVKS RCGLLTSDDS YVVIKKNSDT NGKNENNESN DEEYDGVIDL 120
  121 STNENGNVKS IQFNDDIYCN DDYCNRWKNE NNCISKIGVE DQGNCASSWA FASKLHFETL 180
  181 RCMKGYDHLG ISALYLTNCS KGKISKRCTE GGNPSEFLEI VSNSGFLPTE FDYPYFYALV 240
  241 ENSCPSGLNK WINLWEDVKL FDYKYEPNSI GSKGYSVYKS EMFKDNMDEY VKMIKSEIKN 300
  301 KGSVIAYINA QSVLTYDFNG KNILNMCGSK TTDHSINVIG YGHYKNKEGE EKSYWLVRNS 360
  361 WGYYWGDEGN FKVDMYGPSN CNYHFINTVL VFNI

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 88.045757
Match: 1cjlA
Description: CRYSTAL STRUCTURE OF A CYSTEINE PROTEASE PROFORM
Matching Structure (courtesy of the PDB):

Predicted Domain #5
Region A:
Residues: [745-932]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 DIPMMNNNEN NKKGLYNYFP KYTHEFYHNF YDQNFGSDNK ISLINSNGSN KNDVNNAYTV  60
   61 HGQSGETEVQ PSQLRSTANQ DSNRGAVTSD PLRTQPETTS TSVKKMDVFQ VLKHVKNSKI 120
  121 KVGLIKYDND DEIGAHHSCT RAYSFDPEKY DECVEFCRKN WEQCKDKPSP GFCLTKLDES 180
  181 KGCFFCYV

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.


YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle