YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|18539480
Organism:	Plasmodium falciparum
Length:	245 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|18539480.

Description	E-value	Query Range	Subject Range
DEOD_XENNA - Purine nucleoside phosphorylase DeoD-type OS=Xenorhabdus nematophila (strain ATCC 19061 / DSM 3370 /... DEOD_XENNE - Purine nucleoside phosphorylase deoD-type OS=Xenorhabdus nematophilus GN=deoD PE=3 SV=1	210.0	[0..3]	[237..1]
gi\|7473748 - pir\|\|D75306 purine nucleoside phosphorylase - Deinococcus radiodurans (strain R1) gi\|15807160, gi\|... - gi\|6459967\|gb\|AAF11716.1\|AE002050_2 purine nucleoside phosphorylase [Deinococcus radiodurans R1], gi...	210.0	[0..3]	[243..66]
gi\|242258488, gi... - gi\|242258488\|ref\|ZP_04803284.1\| purine nucleoside phosphorylase [Thermoanaerobacter sp. X513], gi\|24... gi\|241902447, gi... - gi\|241902447\|ref\|ZP_04787181.1\| purine nucleoside phosphorylase [Thermoanaerobacter brockii subsp. f... DEOD_THEPX - Purine nucleoside phosphorylase DeoD-type OS=Thermoanaerobacter sp. (strain X514) GN=deoD PE=3 SV=1 DEOD_THEP3 - Purine nucleoside phosphorylase DeoD-type OS=Thermoanaerobacter pseudethanolicus (strain ATCC 33223 ...	210.0	[0..4]	[238..1]
DEOD_THETN - Purine nucleoside phosphorylase deoD-type OS=Thermoanaerobacter tengcongensis GN=deoD PE=3 SV=1 DEOD_CALS4 - Purine nucleoside phosphorylase DeoD-type OS=Caldanaerobacter subterraneus subsp. tengcongensis (str...	210.0	[0..4]	[237..1]
gi\|89097830, gi\|... - gi\|89097830\|ref\|ZP_01170717.1\| purine-nucleoside phosphorylase [Bacillus sp. NRRL B-14911], gi\|89087...	209.0	[0..4]	[239..1]
gi\|227885127, gi... - gi\|227885127\|ref\|ZP_04002932.1\| purine-nucleoside phosphorylase [Escherichia coli 83972], gi\|2278379... gi\|26111707, gi\|... - gi\|26251274\|ref\|NP_757314.1\| purine nucleoside phosphorylase [Escherichia coli CFT073], gi\|26111707\|...	208.0	[0..2]	[237..19]
gi\|77973607 - gi\|77973607\|ref\|ZP_00829153.1\| COG0813: Purine-nucleoside phosphorylase [Yersinia frederiksenii ATCC...	208.0	[0..3]	[237..1]
gi\|227811681, gi... - gi\|227811681\|ref\|YP_002811691.1\| purine nucleoside phosphorylase [Vibrio cholerae M66-2], gi\|2270108... gi\|254284780, gi... - gi\|254284780\|ref\|ZP_04959747.1\| purine nucleoside phosphorylase [Vibrio cholerae AM-19226], gi\|19775... gi\|254222441, gi... - gi\|254222441\|ref\|ZP_04916312.1\| purine nucleoside phosphorylase [Vibrio cholerae RC385], gi\|19453636... gi\|9657436, gi\|1... - gi\|9657436\|gb\|AAF95967.1\| purine nucleoside phosphorylase [Vibrio cholerae O1 biovar eltor str. N169... gi\|149738566, gi... - gi\|153827503\|ref\|ZP_01980170.1\| purine nucleoside phosphorylase [Vibrio cholerae MZO-2], gi\|14973856... gi\|11280172 - pir\|\|C82505 purine nucleoside phosphorylase VCA0053 [imported] - Vibrio cholerae (strain N16961 sero... gi\|124116330, gi... - gi\|153212817\|ref\|ZP_01948453.1\| purine nucleoside phosphorylase [Vibrio cholerae 1587], gi\|124116330... gi\|121585921, gi... - gi\|121585921\|ref\|ZP_01675714.1\| purine nucleoside phosphorylase [Vibrio cholerae 2740-80], gi\|121549... gi\|153803124, gi... - gi\|153803124\|ref\|ZP_01957710.1\| purine nucleoside phosphorylase [Vibrio cholerae MZO-3], gi\|12412134... gi\|153224772, gi... - gi\|153224772\|ref\|ZP_01954583.1\| purine nucleoside phosphorylase [Vibrio cholerae MAK 757], gi\|124117... gi\|125622662, gi... - gi\|254224599\|ref\|ZP_04918215.1\| purine nucleoside phosphorylase [Vibrio cholerae V51], gi\|194538049\|... gi\|125619811, gi... - gi\|254850320\|ref\|ZP_05239670.1\| purine nucleoside phosphorylase [Vibrio cholerae MO10], gi\|254846025... gi\|153824091, gi... - gi\|153824091\|ref\|ZP_01976758.1\| purine nucleoside phosphorylase [Vibrio cholerae B33], gi\|126518388\|... gi\|126509397, gi... - gi\|153820062\|ref\|ZP_01972729.1\| purine nucleoside phosphorylase [Vibrio cholerae NCTC 8457], gi\|1265...	208.0	[0..2]	[240..9]
gi\|77959706 - gi\|77959706\|ref\|ZP_00823723.1\| COG0813: Purine-nucleoside phosphorylase [Yersinia bercovieri ATCC 43...	208.0	[0..3]	[237..1]
DEOD_PECAS - Purine nucleoside phosphorylase DeoD-type OS=Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BA... DEOD_ERWCT - Purine nucleoside phosphorylase deoD-type OS=Erwinia carotovora subsp. atroseptica GN=deoD PE=3 SV=1	207.0	[0..3]	[237..1]

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Predicted Domain #1

Region A:
Residues: [1-245]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDNLLRHLKI SKEQITPVVL VVGDPGRVDK IKVVCDSYVD LAYNREYKSV ECHYKGQKFL  60
   61 CVSHGVGSAG CAVCFEELCQ NGAKVIIRAG SCGSLQPDLI KRGDICICNA AVREDRVSHL 120
  121 LIHGDFPAVG DFDVYDTLNK CAQELNVPVF NGISVSSDMY YPNKIIPSRL EDYSKANAAV 180
  181 VEMELATLMV IGTLRKVKTG GILIVDGCPF KWDEGDFDNN LVPHQLENMI KIALGACAKL 240
  241 ATKYA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	47.09691
Match:	2bsxA
Description:	Crystal structure of the Plasmodium falciparum purine nucleoside phosphorylase complexed with inosine
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
purine-nucleoside phosphorylase activity	3.68206997938506	bayes_pls_golite062009
transferase activity, transferring glycosyl groups	3.66765825367784	bayes_pls_golite062009
catalytic activity	2.18268586151113	bayes_pls_golite062009
transferase activity, transferring pentosyl groups	2.01261001022129	bayes_pls_golite062009
S-methyl-5-thioadenosine phosphorylase activity	1.6959166270803	bayes_pls_golite062009
transferase activity	1.42022417161912	bayes_pls_golite062009
nucleobase binding	1.33291775180025	bayes_pls_golite062009
nucleoside binding	1.11256863177576	bayes_pls_golite062009
purine binding	1.00226077276304	bayes_pls_golite062009
binding	0.192121943858605	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: