YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|16805183, gi\|...
Organism:	Plasmodium falciparum 3D7
Length:	955 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|16805183, gi|....

Description	E-value	Query Range	Subject Range
gi\|94386253, gi\|... - gi\|94387428\|ref\|XP_991095.1\| PREDICTED: similar to CG11596-PA, isoform A [Mus musculus], gi\|94386253...	383.0	[0..697]	[950..180]
gi\|114625050 - gi\|114625050\|ref\|XP_528328.2\| PREDICTED: similar to Chromosome 9 open reading frame 41 [Pan troglody...	382.0	[0..697]	[950..219]
gi\|30685200 - gi\|30685200\|ref\|NP_180775.2\| unknown protein [Arabidopsis thaliana]	378.0	[0..632]	[949..125]
gi\|109111848 - gi\|109111848\|ref\|XP_001094584.1\| PREDICTED: similar to CG11596-PA, isoform A [Macaca mulatta]	373.0	[0..697]	[950..344]
CARME_RAT - Carnosine N-methyltransferase OS=Rattus norvegicus GN=Carnmt1 PE=1 SV=1	369.0	[0..697]	[950..144]
C9orf41 - chromosome 9 open reading frame 41 gi\|190690459, gi... - gi\|190691835\|gb\|ACE87692.1\| chromosome 9 open reading frame 41 protein [synthetic construct], gi\|190... ENSPTRT00000038890 - null	369.0	[0..697]	[950..153]
gi\|73946783 - gi\|73946783\|ref\|XP_533523.2\| PREDICTED: similar to CG11596-PA, isoform A [Canis familiaris]	368.0	[0..697]	[950..155]

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Predicted Domain #1

Region A:
Residues: [1-124]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVTGGQGKLN QKNQKGDKKN LSYDNKINNN INISVVEKSE GNYKESYVFY KKDMCDENNN  60
   61 ISNMEGIDQF HNCNNEQKKI DTTTITTYNN NINSSSNNNY NNDYDIDENN NFHCHDDDHK 120
  121 HLDN

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted Domain #2

Region A:
Residues: [125-258]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YCVKDDYSHE DNDQCHVCNT VDMLNLEEER HFCNVCFSFL YYKKYCFYEL LRIYKNYSCL  60
   61 NEEEKNLLTE SIYAKLYKMY LTTLNNYYFI LNILLPQIST HIIIHLLTFT FHKPEEDEHM 120
  121 KEEYVMNEII NKLT

[Run NCBI BLAST on this sequence.]

Detection Method:

deduced

Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.

		MCM Score	SCOP Match	SCOP Description
View	Download	0.862	a.151.1	Glutamyl tRNA-reductase dimerization domain
View	Download	0.845	a.19.1	Fertilization protein
View	Download	0.715	a.151.1	Glutamyl tRNA-reductase dimerization domain
View	Download	0.701	a.27.1	Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases
View	Download	0.698	a.7.1	Spectrin repeat

Predicted Domain #3

Region A:
Residues: [259-354]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NQELNNIDKV YNYHNFNVRL LCKDDALIIL NEIRSKMINS QNEKKIVDML NMKCGDVIVD  60
   61 DKNGSDKDSG NNDIHNKDIH NKYDDNMDSS DKSSCN

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	4.69897
Match:	1jv2B
Description:	Hybrid domain of integrin beta; Integrin beta A domain; Integrin beta tail domain; Integrin beta EGF-like domains
Matching Structure (courtesy of the PDB):

Predicted Domain #4

Region A:
Residues: [355-696]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KNSCDNHCDN HCDNHSDNHC DNHSDNHCDN HCDNHCDNHC DNHCDNHCDN HCDNHCDNHC  60
   61 DNHCDNHCDN HCDNHCDNHC DNHCDNHCDN HSDNHCDNHC DNHCDNHCDN HCDNHCDNHC 120
  121 DNHSDNHCDN HCDNHSDNHC DNHCDNHSDN HCDNHCDNHC DNHCDNHCDN HCDNHCDNHC 180
  181 DNHCDNHCDN HCDNHCDNHC DNHCDNHCDN HCDNHCDNNK MNRTHLMNSN TKGDDQTCKN 240
  241 TNEYSDTSSN HYCNNIEEDT YNVVNPGVDL DVHNIIDSKN IKDYHNDIKE NMCNNNKTLH 300
  301 ADENMPNDNI CARENNSKYE HTPPGMRISQ AYTPTLDDYN LI

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	32.522879
Match:	1n7dA
Description:	Low density lipoprotein (LDL) receptor YWTD domain; Low density lipoprotein (LDL) receptor, different EGF domains; Ligand-binding domain of low-density lipoprotein receptor
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	0.286076792172079	bayes_pls_golite062009
protein binding	0.14494900666454	bayes_pls_golite062009

Predicted Domain #5

Region A:
Residues: [697-955]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QNMSKVRSTL RQFVRDWSME GQEERDKAYI PLINSLDKYL PIHDNYIPKI LCPGSGLGRL  60
   61 PYEIAKKGYR SQGNEFSYFM LLGSNFILNY YNEKYSLSIH PYCLCTSNRR GRDDHLKIIQ 120
  121 LPDVNTYNKI VLNTDFSMCA GELIEVYYYD KEYFDGVLTC FFLDTAKNLF MYIRTFASIL 180
  181 KPNSLWSNIG PLLYHYAEMP NEMSIELAWD EIQIIISKWF TIKEIKWIDN YYTTNFDSMM 240
  241 QVQYHCVFFS AIRNDIPVD

[Run NCBI BLAST on this sequence.]

Detection Method:	FFAS03
Confidence:	1.89
Match:	2bzgA
Description:	Crystal structure of thiopurine S-methyltransferase.
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
catalytic activity	0.639646908254091	bayes_pls_golite062009
transferase activity	0.394707018913607	bayes_pls_golite062009
transferase activity, transferring one-carbon groups	0.0810339077201343	bayes_pls_golite062009
methyltransferase activity	0.0737551340470768	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions:

Predicted functions: