YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: gi|7494185
Organism: Plasmodium falciparum
Length: 1365 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|7494185.

Description E-value Query
Range
Subject
Range
gi|114614720 - gi|114614720|ref|XP_001160982.1| PREDICTED: ATP-binding cassette, subfamily B, member 4 [Pan troglod...
686.0 [0..141] [1359..339]
MDR1_CRIGR - Multidrug resistance protein 1 OS=Cricetulus griseus GN=ABCB1 PE=1 SV=2
683.0 [0..125] [1359..4]
gi|57526446, gi|... - gi|57526446|ref|NP_001009790.1| ATP-binding cassette, subfamily B, member 1 [Ovis aries], gi|2149087...
683.0 [0..134] [1359..19]
gi|191155 - gi|191155|gb|AAA37004.1| p-glycoprotein
gi|72477 - pir||DVHY1C multidrug resistance protein 1 - Chinese hamster
682.0 [0..125] [1359..4]
gi|46394982 - gi|46394982|gb|AAS91647.1| multidrug resistance protein 1; P-glycoprotein [Canis familiaris]
678.0 [0..151] [1359..32]
MDR1B_MOUSE - Multidrug resistance protein 1B OS=Mus musculus GN=Abcb1b PE=1 SV=1
678.0 [0..131] [1359..10]
gi|8926217 - gi|8926217|gb|AAF81747.1| his-tagged-multidrug resistance glycoprotein MDR1 [synthetic construct]
677.0 [0..151] [1359..38]

Back

Predicted Domain #1
Region A:
Residues: [1-64]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKYLFFSLFL CYNLIVYIYC VSKNAYNIKE KRRGECNFPI NNQRCNNNMN SLIMNKYLYK  60
   61 KRKH

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [65-147]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 SNTLPFIKTY NNFKEKNKND VVQISYYSIN HNKKYNNKIH THILFMNNNN NNNNNSNSNK  60
   61 EYIKANNANM LFSIYNKISE DGK

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #3
Region A:
Residues: [148-728]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TKNSLLSDIS KLFKIVKESK LIFVTGFLLT TLSAIVDSYI PIFLSKTVSF VMERKKFTFL  60
   61 KIHKTNLSVV KNLIEYLKFY STNPFHMYVL ISVISLLFSS FRSYIFNVCA YVSTNKLQKY 120
  121 LFNVLLHKNI NYFKKKGKGE LISRLNIDSS ELIDIFTTNI IVLFRNMIKM ALSFYFLYKI 180
  181 NVHLFIVSLF IVFIISNISI FFSNIFRKLA KEESNVVAQS NNIVEESIYN FSLISTFNTH 240
  241 NKEIKKYNNS LDTIYMSRMK LGLLYIIEKF FIRLIDMMTF ILTLILSKKT LMYNLNTDTR 300
  301 TIISSVIYMQ NIIAQSCIIE QQYSRVQELI GNAEEVIKLI EKDNMRNNNN NNNNDNIKLV 360
  361 SNKYNFFSIL FNINDMKNFI FNHSLLKKFQ TIQNNSDYVF NIIKPNYLKL FERNYNNLIK 420
  421 LFFNEKNFNQ CDESLFKNGS IDDINNIDMY EKKEETNKIN DYHNFISNKQ MYDNKTKDCT 480
  481 LKKKKQDNSF YYNTPNNNVE MKNQLDQHSF SKSENFQNKL KKKIQEINMQ EVYQFIKNDH 540
  541 ALIIKYKLDR KFIRFLKTNY KKNIILLILK LYKERNNSVS D

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 118.0
Match: 2hydA
Description: No description for 2hydA was found.

Predicted Domain #4
Region A:
Residues: [729-1141]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NFLFLFDNIS SFKNLSIKDK KSILKMSNIT NKTIYIILLT FLFYNYSKFY YKKQKKKNFI  60
   61 NFIEKKNKML KNNQNVERGQ HGSSTYEKMY ESMDDEININ DVLSDAISDT ICDNSNDTIR 120
  121 DNSNDTICDN SNNTICDNSN DTICDNSNVI SSNYQSNQHL YPQIMSTTPN KNDQYNNPTD 180
  181 NLELNNESVI LNKTKSRTKK KRNLYNILPY IVENAIKELE ILKFIDANYK SINENLILDN 240
  241 IKDNQKGSTL IFENVDFYFA KYPKNKILSN INLNFSNKYT YGILCYNDSG KNYLAKLAAR 300
  301 LYNKTYGNIL LDDENIENIS KYILTKKISL VEEQSYIFSD SIIYNMLYSY NCITKGNKNF 360
  361 YYLNYNFKLN KNNINNCVHL FSHDNDITTN DYNNNNINKN INSDNYSSSS SSN

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 6.61
Match: 2hydA
Description: No description for 2hydA was found.

Predicted Domain #5
Region A:
Residues: [1142-1365]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TISSCRNYEQ YEKIKEKNKK PKIKYKIKEN KPSIYNIHNT TNNNTVDQSL YTFKNFKKKC  60
   61 LMCGSLIDTK LLEEQKKSPN YNKYKVHFIK KLYKEIIKVS KIVCLYDVIN SYPDKFFHNI 120
  121 NDKILSGGQK QKISLARAII KKPKILILDD AFSALDAANE LKIFSSLKNY LPNCTIVNLS 180
  181 HKITTVNKCD YIYVLKDGKI IEHGLRTKLI QNRNSEYIKK FNEY

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 72.09691
Match: 1mt0A
Description: Haemolysin B ATP-binding protein
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
catalytic activity 0.470983068319171 bayes_pls_golite062009
hydrolase activity 0.0582794297634999 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle